{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T04:55:23Z","timestamp":1761540923225,"version":"3.37.0"},"reference-count":49,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2009,12,1]],"date-time":"2009-12-01T00:00:00Z","timestamp":1259625600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["International Journal of Radiation Oncology*Biology*Physics"],"published-print":{"date-parts":[[2009,12]]},"DOI":"10.1016\/j.ijrobp.2009.01.022","type":"journal-article","created":{"date-parts":[[2009,5,23]],"date-time":"2009-05-23T08:56:36Z","timestamp":1243068996000},"page":"1392-1400","source":"Crossref","is-referenced-by-count":11,"title":["Stereotactic Interstitial Radiosurgery With the Photon Radiosurgery System (PRS) for Metastatic Brain Tumors: A Prospective Single-Center Clinical Trial"],"prefix":"10.1016","volume":"75","author":[{"given":"Georgios","family":"Pantazis","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Trippel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Walter","family":"Birg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christoph B.","family":"Ostertag","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guido","family":"Nikkhah","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ijrobp.2009.01.022_bib1","doi-asserted-by":"crossref","first-page":"156","DOI":"10.3109\/07357909409024871","article-title":"Management of brain metastases","volume":"12","author":"De Angelis","year":"1994","journal-title":"Cancer Invest"},{"key":"10.1016\/j.ijrobp.2009.01.022_bib2","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/0167-8140(93)90091-L","article-title":"Results of a randomized clinical trial comparing two radiation schedules in the palliative treatment of brain metastases","volume":"26","author":"Haie\u2013Meder","year":"1993","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.ijrobp.2009.01.022_bib3","first-page":"81","article-title":"Stereotactic radiosurgery for inracranial malignancies","volume":"81","author":"Flickinger","year":"1994","journal-title":"Oncology"},{"key":"10.1016\/j.ijrobp.2009.01.022_bib4","first-page":"195","article-title":"Special stereotactic techniques: Stereotactic radiosurgery","volume":"Vol. 2","author":"Leksell","year":"1988"},{"key":"10.1016\/j.ijrobp.2009.01.022_bib5","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1227\/00006123-199302000-00014","article-title":"Stereotactic radiosurgery. Principles and comparison of treatment methods","volume":"32","author":"Luxton","year":"1993","journal-title":"Neurosurgery"},{"key":"10.1016\/j.ijrobp.2009.01.022_bib6","series-title":"Radiosurgery: Baseline and trends","first-page":"3","article-title":"Radiobiological fundamentals in radiosurgery","author":"Larsson","year":"1992"},{"key":"10.1016\/j.ijrobp.2009.01.022_bib7","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1016\/S1042-3680(18)30374-7","article-title":"Interstitial brachytherapy for intracranial metastases","volume":"7","author":"McDermott","year":"1996","journal-title":"Neurosurg Clin North Am"},{"key":"10.1016\/j.ijrobp.2009.01.022_bib8","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1016\/S0360-3016(00)00475-2","article-title":"Hypofractionated stereotactic radiotherapy as an alternative to radiosurgery for the treatment of patients with brain metastases","volume":"47","author":"Manning","year":"2000","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2009.01.022_bib9","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1118\/1.597790","article-title":"A new miniature x-ray source for interstitial radiosurgery: Device description","volume":"23","author":"Dinsmore","year":"1996","journal-title":"Med Phys"},{"key":"10.1016\/j.ijrobp.2009.01.022_bib10","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1118\/1.597791","article-title":"A new miniature x-ray device for interstitial radiosurgery: Dosimetry","volume":"23","author":"Beatty","year":"1996","journal-title":"Med Phys"},{"key":"10.1016\/j.ijrobp.2009.01.022_bib11","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1016\/S0360-3016(96)00293-3","article-title":"Dosimetric results from a feasibility study of a novel radiosurgical source for irradiation of intracranial metastases","volume":"36","author":"Douglas","year":"1996","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2009.01.022_bib12","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1088\/0031-9155\/44\/2\/002","article-title":"Clinical relative biological effectiveness of low-energy x-rays emitted by miniature x-ray devices","volume":"44","author":"Brenner","year":"1999","journal-title":"Phys Med Biol"},{"key":"10.1016\/j.ijrobp.2009.01.022_bib13","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1016\/S0360-3016(00)00472-7","article-title":"Preclinical studies with the photon radiosurgery system (PRS)","volume":"47","author":"Astor","year":"2000","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2009.01.022_bib14","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1055\/s-2000-11373","article-title":"Early effects of PRS-irradiation for 9L gliosarcoma: Characterisation of interphase cell death","volume":"43","author":"Kurita","year":"2000","journal-title":"Minim Invas Neurosurg"},{"key":"10.1016\/j.ijrobp.2009.01.022_bib15","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1055\/s-2003-39343","article-title":"Radiobiological effects of photon radiosurgery on choroid plexus cells in vitro","volume":"6","author":"Niu","year":"2003","journal-title":"Minim Invasive Neurosurg"},{"key":"10.1016\/j.ijrobp.2009.01.022_bib16","first-page":"510","article-title":"Initial characterization of the dosimetry and radiobiology of a device for administering interstitial stereotactic radiosurgery","volume":"40","author":"Hakim","year":"1997","journal-title":"Neurosurgery"},{"key":"10.1016\/j.ijrobp.2009.01.022_bib17","first-page":"518","article-title":"Interstitial irradiation of brain tumors using a miniature radiosurgery device: Initial experience","volume":"40","author":"Cosgrove","year":"1997","journal-title":"Neurosurgery"},{"key":"10.1016\/j.ijrobp.2009.01.022_bib18","doi-asserted-by":"crossref","first-page":"1277","DOI":"10.1200\/JCO.1990.8.7.1277","article-title":"Response criteria for Phase II studies of supratentorial malignant glioma","volume":"8","author":"Macdonald","year":"1990","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.ijrobp.2009.01.022_bib19","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1080\/01621459.1958.10501452","article-title":"Non-parametric estimation from incomplete observations","volume":"53","author":"Kaplan","year":"1958","journal-title":"J Am Stat Assoc"},{"key":"10.1016\/j.ijrobp.2009.01.022_bib20","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1111\/j.2517-6161.1972.tb00899.x","article-title":"Regression models and life tables","volume":"34","author":"Cox","year":"1966","journal-title":"J R Stat Soc"},{"key":"10.1016\/j.ijrobp.2009.01.022_bib21","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1016\/S0360-3016(96)00619-0","article-title":"Recursive partitioning analysis (RPA) of prognostic factors in three Radiation Therapy Oncology Group (RTOG) brain metastases trials","volume":"37","author":"Gaspar","year":"1997","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2009.01.022_bib22","doi-asserted-by":"crossref","first-page":"1155","DOI":"10.1016\/S0360-3016(99)00549-0","article-title":"Radiosurgery for brain metastases: A score index for predicting prognosis","volume":"46","author":"Weltman","year":"2000","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2009.01.022_bib23","doi-asserted-by":"crossref","first-page":"1231","DOI":"10.1016\/0360-3016(93)90548-A","article-title":"Radiation Therapy Oncology Group: Radiosurgery quality assurance guidelines","volume":"7","author":"Shaw","year":"1993","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2009.01.022_bib24","doi-asserted-by":"crossref","first-page":"1341","DOI":"10.1016\/0360-3016(95)00060-C","article-title":"Toxicity criteria of the Radiation Therapy Oncology Group (RTOG) and the European Organization for Research and Treatment of Cancer (EORTC)","volume":"31","author":"Cox","year":"1995","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2009.01.022_bib25","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1016\/0360-3016(95)02106-X","article-title":"Radiosurgery for the treatment of previously irradiated recurrent primary brain tumors and brain metastases: Initial report of radiation therapy oncology group protocol (90-105)","volume":"34","author":"Shaw","year":"1996","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2009.01.022_bib26","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1148\/radiology.211.3.r99jn48807","article-title":"MR imaging response of intracranial metastases after Gamma-knife stereotactic radiosurgery","volume":"211","author":"Peterson","year":"1999","journal-title":"Radiology"},{"key":"10.1016\/j.ijrobp.2009.01.022_bib27","doi-asserted-by":"crossref","first-page":"1339","DOI":"10.1016\/S0360-3016(00)01511-X","article-title":"Transient enlargement of contrast uptake on MRI after Linear Accelerator (Linac) stereotactic radiosurgery for brain metastases","volume":"49","author":"Huber","year":"2001","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2009.01.022_bib28","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1002\/1097-0142(19890215)63:4<657::AID-CNCR2820630410>3.0.CO;2-Q","article-title":"Interstitial brachytherapy for metastatic brain tumors","volume":"63","author":"Prados","year":"1989","journal-title":"Cancer"},{"key":"10.1016\/j.ijrobp.2009.01.022_bib29","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1017\/S0317167100040439","article-title":"Brachytherapy for recurrent single brain metastases","volume":"22","author":"Bernstein","year":"1995","journal-title":"Can J Neurol Sci"},{"key":"10.1016\/j.ijrobp.2009.01.022_bib30","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1080\/02688699550040873","article-title":"Interstitial iodine-125 radiosurgery for cerebral metastases","volume":"9","author":"Ostertag","year":"1995","journal-title":"Br J Neurosurg"},{"key":"10.1016\/j.ijrobp.2009.01.022_bib31","doi-asserted-by":"crossref","first-page":"1351","DOI":"10.1002\/1097-0142(19930215)71:4<1353::AID-CNCR2820710430>3.0.CO;2-6","article-title":"Long-term follow-up for brain metastases treated by percutaneous stereotactic single high-dose irradiation","volume":"71","author":"Engenhart","year":"1993","journal-title":"Cancer"},{"key":"10.1016\/j.ijrobp.2009.01.022_bib32","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1016\/S0360-3016(99)00507-6","article-title":"Single dose radiosurgical treatment of recurrent previously irradiated primary brain tumors and brain metastases: Final report of RTOG Protocol 90-05","volume":"47","author":"Shaw","year":"2000","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2009.01.022_bib33","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1016\/0360-3016(94)90098-1","article-title":"A multi-institutional experience with stereotactic radiosurgery for solitary brain metastasis","volume":"28","author":"Flickinger","year":"1994","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2009.01.022_bib34","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1016\/0360-3016(94)90558-4","article-title":"The choice of treatment of single brain metastasis should be based on extracranial tumour activity and age","volume":"29","author":"Noordijk","year":"1994","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2009.01.022_bib35","doi-asserted-by":"crossref","first-page":"1485","DOI":"10.1001\/jama.280.17.1485","article-title":"Postoperative radiotherapy in the treatment of single metastasis to the brain","volume":"280","author":"Patchell","year":"1998","journal-title":"JAMA"},{"key":"10.1016\/j.ijrobp.2009.01.022_bib36","doi-asserted-by":"crossref","first-page":"209","DOI":"10.3171\/jns.2005.102.2.0209","article-title":"Resection of brain metastases previously treated with stereotactic radiosurgery","volume":"102","author":"Vecil","year":"2005","journal-title":"J Neurosurg"},{"key":"10.1016\/j.ijrobp.2009.01.022_bib37","doi-asserted-by":"crossref","first-page":"630","DOI":"10.3171\/jns.2005.103.4.0630","article-title":"Stereotactic interstitial radiosurgery for cerebral metastases","volume":"103","author":"Curry","year":"2005","journal-title":"J Neurosurg"},{"key":"10.1016\/j.ijrobp.2009.01.022_bib38","doi-asserted-by":"crossref","first-page":"1066","DOI":"10.1227\/01.NEU.0000057695.46198.FE","article-title":"Radiosurgery followed by planned observation in patients with one to three brain metastases","volume":"52","author":"Lutterbach","year":"2003","journal-title":"Neurosurgery"},{"key":"10.1016\/j.ijrobp.2009.01.022_bib39","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1023\/A:1006169109920","article-title":"Patient selection criteria for the treatment of brain metastases with stereotactic radiosurgery","volume":"40","author":"Cho","year":"1998","journal-title":"J Neurooncol"},{"key":"10.1016\/j.ijrobp.2009.01.022_bib40","doi-asserted-by":"crossref","first-page":"2265","DOI":"10.1002\/(SICI)1097-0258(19981015)17:19<2265::AID-SIM918>3.0.CO;2-B","article-title":"Propensity score methods for bias reduction in the comparison of a treatment to a non-randomized control group","volume":"17","author":"D'Agostino","year":"1998","journal-title":"Stat Med"},{"key":"10.1016\/j.ijrobp.2009.01.022_bib41","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1093\/jnci\/87.1.34","article-title":"Stereotactic radiosurgery for the definitive noninvasive treatment of brain metastases","volume":"87","author":"Alexander","year":"1995","journal-title":"J Nat Cancer Inst"},{"key":"10.1016\/j.ijrobp.2009.01.022_bib42","doi-asserted-by":"crossref","first-page":"444","DOI":"10.3171\/jns.1992.76.3.0444","article-title":"Stereotactic radiosurgical treatment of brain metastases","volume":"76","author":"Adler","year":"1992","journal-title":"J Neurosurg"},{"key":"10.1016\/j.ijrobp.2009.01.022_bib43","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1016\/0360-3016(92)90706-N","article-title":"Defining the role of stereotactic radiosurgery in the management of brain metastases","volume":"24","author":"Mehta","year":"1992","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2009.01.022_bib44","first-page":"335","article-title":"Factors influencing survival after Gamma-Knife radiosurgery for patients with single and multiple brain metastases","volume":"2","author":"Shu","year":"1996","journal-title":"Cancer J Sci Am"},{"key":"10.1016\/j.ijrobp.2009.01.022_bib45","first-page":"83","article-title":"Long-term follow up of patients treated with stereotactic radiosurgery for single or multiple brain metastases","volume":"Vol. 1","author":"Moriarty","year":"1995"},{"key":"10.1016\/j.ijrobp.2009.01.022_bib46","doi-asserted-by":"crossref","first-page":"2075","DOI":"10.1002\/(SICI)1097-0142(19971201)80:11<2075::AID-CNCR6>3.0.CO;2-W","article-title":"Stereotactic radiosurgery for patients with nonsmall cell lung carcinoma metastatic to the brain","volume":"80","author":"Kim","year":"1997","journal-title":"Cancer"},{"key":"10.1016\/j.ijrobp.2009.01.022_bib47","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/S0360-3016(00)01584-4","article-title":"Relationship between pattern of enhancement and local control of brain metastases after radiosurgery","volume":"50","author":"Goodman","year":"2001","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2009.01.022_bib48","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1016\/S0360-3016(96)00497-X","article-title":"Radiosurgery for brain metastases: relationship of dose and pattern of enhancement to local control","volume":"37","author":"Shiau","year":"1997","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2009.01.022_bib49","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1007\/978-3-7091-9371-6_15","article-title":"Linac radiosurgery in brain metastases","volume":"62","author":"Voges","year":"1994","journal-title":"Acta Neurochir Suppl (Wien)"}],"container-title":["International Journal of Radiation Oncology*Biology*Physics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0360301609001035?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0360301609001035?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,2,9]],"date-time":"2025-02-09T17:40:22Z","timestamp":1739122822000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0360301609001035"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,12]]},"references-count":49,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2009,12]]}},"alternative-id":["S0360301609001035"],"URL":"https:\/\/doi.org\/10.1016\/j.ijrobp.2009.01.022","relation":{},"ISSN":["0360-3016"],"issn-type":[{"type":"print","value":"0360-3016"}],"subject":[],"published":{"date-parts":[[2009,12]]}}}