{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T18:03:22Z","timestamp":1791223402101,"version":"4.1.0"},"reference-count":12,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2010,9,1]],"date-time":"2010-09-01T00:00:00Z","timestamp":1283299200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["International Journal of Radiation Oncology*Biology*Physics"],"published-print":{"date-parts":[[2010,9]]},"DOI":"10.1016\/j.ijrobp.2009.07.1680","type":"journal-article","created":{"date-parts":[[2010,1,8]],"date-time":"2010-01-08T10:36:05Z","timestamp":1262946965000},"page":"19-25","source":"Crossref","is-referenced-by-count":108,"title":["Urinary Obstruction in Prostate Cancer Patients From the Dutch Trial (68 Gy vs. 78 Gy): Relationships With Local Dose, Acute Effects, and Baseline Characteristics"],"prefix":"10.1016","volume":"78","author":[{"given":"Wilma D.","family":"Heemsbergen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abrahim","family":"Al-Mamgani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marnix G.","family":"Witte","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcel","family":"van Herk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Floris J.","family":"Pos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joos V.","family":"Lebesque","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ijrobp.2009.07.1680_bib1","doi-asserted-by":"crossref","first-page":"980","DOI":"10.1016\/j.ijrobp.2008.02.073","article-title":"Update of Dutch multicenter dose-escalation trial of radiotherapy for localized prostate cancer","volume":"72","author":"Al-Mamgani","year":"2008","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2009.07.1680_bib2","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1016\/j.juro.2007.03.126","article-title":"Incidence of urethral stricture after primary treatment for prostate cancer: Data from CaPSURE","volume":"178","author":"Elliott","year":"2007","journal-title":"J Urol"},{"key":"10.1016\/j.ijrobp.2009.07.1680_bib3","doi-asserted-by":"crossref","first-page":"1100","DOI":"10.1016\/j.ijrobp.2007.04.076","article-title":"Predictors for chronic urinary toxicity after the treatment of prostate cancer with adaptive 3D conformal RT: Dose\u2013volume analysis of a Phase III dose-escalation study","volume":"69","author":"Harsolia","year":"2007","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2009.07.1680_bib4","doi-asserted-by":"crossref","first-page":"1019","DOI":"10.1016\/j.ijrobp.2004.07.715","article-title":"Acute and late complications after radiotherapy for prostate cancer: Results of a multi-center randomized trial comparing 68 Gy with 78 Gy","volume":"61","author":"Peeters","year":"2005","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2009.07.1680_bib5","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1016\/S0360-3016(00)00714-8","article-title":"Long-term urinary toxicity after 3D CRT for prostate cancer in patients with prior history of TURP","volume":"48","author":"Sandhu","year":"2000","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2009.07.1680_bib6","doi-asserted-by":"crossref","first-page":"2460","DOI":"10.1002\/(SICI)1097-0142(19990601)85:11<2460::AID-CNCR23>3.0.CO;2-N","article-title":"Long term tolerance of high dose 3D-CRT in patients with localized prostate carcinoma","volume":"85","author":"Zelefsky","year":"1999","journal-title":"Cancer"},{"key":"10.1016\/j.ijrobp.2009.07.1680_bib7","doi-asserted-by":"crossref","first-page":"1478","DOI":"10.1016\/j.ijrobp.2007.08.076","article-title":"Late GI morbidity after 3D-CRT for prostate cancer fades with time in contrast to GU morbidity","volume":"70","author":"Karlssdottir","year":"2008","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2009.07.1680_bib8","doi-asserted-by":"crossref","first-page":"3589","DOI":"10.1088\/0031-9155\/50\/15\/007","article-title":"Absolute and relative dose-surface and dose-volume histograms of the bladder; which one is the most invariant under bladder filling changes?","volume":"50","author":"Hoogeman","year":"2005","journal-title":"Phys Med Biol"},{"key":"10.1016\/j.ijrobp.2009.07.1680_bib9","doi-asserted-by":"crossref","first-page":"1059","DOI":"10.1016\/j.ijrobp.2006.10.042","article-title":"Investigation of bladder dose and volume factors influencing late urinary toxicity after external beam radiotherapy for prostate cancer","volume":"67","author":"Cheung","year":"2007","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2009.07.1680_bib10","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1016\/S1470-2045(07)70143-2","article-title":"Escalated-dose versus standard-dose conformal radiotherapy in prostate cancer: First results from the MRC RT01 randomized controlled trial","volume":"8","author":"Dearnaley","year":"2007","journal-title":"Lancet Oncol"},{"key":"10.1016\/j.ijrobp.2009.07.1680_bib11","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.ijrobp.2007.06.054","article-title":"Long-term results of the MD Anderson randomized dose-escalation trial for prostate cancer","volume":"70","author":"Kuban","year":"2008","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2009.07.1680_bib12","doi-asserted-by":"crossref","first-page":"706","DOI":"10.1016\/j.ijrobp.2004.11.028","article-title":"Toxicity after 3D radiotherapy for prostate cancer on RTOG 9406 dose level V","volume":"62","author":"Michalski","year":"2005","journal-title":"Int J Radiat Oncol Biol Phys"}],"container-title":["International Journal of Radiation Oncology*Biology*Physics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0360301609027850?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0360301609027850?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,12,14]],"date-time":"2018-12-14T04:24:07Z","timestamp":1544761447000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0360301609027850"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,9]]},"references-count":12,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2010,9]]}},"alternative-id":["S0360301609027850"],"URL":"https:\/\/doi.org\/10.1016\/j.ijrobp.2009.07.1680","relation":{},"ISSN":["0360-3016"],"issn-type":[{"value":"0360-3016","type":"print"}],"subject":[],"published":{"date-parts":[[2010,9]]}}}