{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T12:44:21Z","timestamp":1787316261524,"version":"build-2736575974"},"reference-count":12,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2011,1,1]],"date-time":"2011-01-01T00:00:00Z","timestamp":1293840000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["International Journal of Radiation Oncology*Biology*Physics"],"published-print":{"date-parts":[[2011,1]]},"DOI":"10.1016\/j.ijrobp.2009.10.043","type":"journal-article","created":{"date-parts":[[2010,4,15]],"date-time":"2010-04-15T05:07:59Z","timestamp":1271308079000},"page":"158-162","source":"Crossref","is-referenced-by-count":119,"title":["Intensity-Modulated Radiation Therapy Significantly Improves Acute Gastrointestinal Toxicity in Pancreatic and Ampullary Cancers"],"prefix":"10.1016","volume":"79","author":[{"given":"Susannah","family":"Yovino","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew","family":"Poppe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Salma","family":"Jabbour","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vera","family":"David","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Garofalo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naimesh","family":"Pandya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard","family":"Alexander","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nader","family":"Hanna","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William F.","family":"Regine","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ijrobp.2009.10.043_bib1","doi-asserted-by":"crossref","first-page":"1019","DOI":"10.1001\/jama.299.9.1019","article-title":"Fluorouracil vs gemcitabine chemotherapy before and after fluorouracil-based chemoradiation following resection of pancreatic adenocarcinoma: A randomized controlled trial","volume":"299","author":"Regine","year":"2008","journal-title":"JAMA"},{"key":"10.1016\/j.ijrobp.2009.10.043_bib2","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1007\/s00345-003-0356-x","article-title":"Radiation therapy dose escalation for prostate cancer: A rationale for IMRT","volume":"21","author":"Pollack","year":"2003","journal-title":"World J Urol"},{"key":"10.1016\/j.ijrobp.2009.10.043_bib3","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/S0360-3016(02)02724-4","article-title":"Intensity-modulated radiotherapy in the treatment of nasopharyngeal carcinoma: An update of the UCSF experience","volume":"53","author":"Lee","year":"2002","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2009.10.043_bib4","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1016\/S0360-3016(99)00247-3","article-title":"Dose, volume, and function relationships in parotid salivary glands following conformal and intensity-modulated irradiation of head and neck cancer","volume":"45","author":"Eisbruch","year":"1999","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2009.10.043_bib5","doi-asserted-by":"crossref","first-page":"1215","DOI":"10.1016\/j.ijrobp.2008.07.010","article-title":"Evaluation of four-dimensional computed-tomography-based intensity-modulated and respiratory-gated radiotherapy techniques for pancreatic carcinoma","volume":"72","author":"Van der Geld","year":"2008","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2009.10.043_bib6","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/S0958-3947(02)00094-8","article-title":"Treatment of pancreatic cancer tumors with intensity-modulated radiation therapy using the volume at risk approach: Employing dose-volume histogram and normal tissue complication probability to evaluate small bowel toxicity","volume":"27","author":"Landry","year":"2002","journal-title":"Med Dosim"},{"key":"10.1016\/j.ijrobp.2009.10.043_bib7","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1016\/j.ijrobp.2003.11.003","article-title":"Intensity-modulated radiotherapy in treatment of pancreatic and bile duct malignancies: Toxicity and clinical outcome","volume":"59","author":"Milano","year":"2004","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2009.10.043_bib8","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1016\/j.ijrobp.2003.11.019","article-title":"Intensity-modulated radiotherapy and concurrent capecitabine for pancreatic cancer","volume":"59","author":"Ben-Josef","year":"2004","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2009.10.043_bib9","doi-asserted-by":"crossref","first-page":"1330","DOI":"10.1016\/S0360-3016(01)02785-7","article-title":"Intensity-modulated whole pelvic radiotherapy in women with gynecologic malignancies","volume":"52","author":"Mundt","year":"2002","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2009.10.043_bib10","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1001\/jama.297.3.267","article-title":"Adjuvant chemotherapy with gemcitabine vs. observation in patients undergoing curative-intent resection of pancreatic cancer: A randomized controlled trial","volume":"297","author":"Oettle","year":"2007","journal-title":"JAMA"},{"key":"10.1016\/j.ijrobp.2009.10.043_bib11","unstructured":"Regine WF (RTOG 0848 co-investigator). Personal communication."},{"key":"10.1016\/j.ijrobp.2009.10.043_bib12","doi-asserted-by":"crossref","first-page":"884","DOI":"10.1016\/j.ijrobp.2009.02.003","article-title":"Characterization of pancreatic tumor motion using cine MRI: Surrogates for tumor position should be used with caution","volume":"74","author":"Feng","year":"2009","journal-title":"Int J Radiat Oncol Biol Phys"}],"container-title":["International Journal of Radiation Oncology*Biology*Physics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S036030160903510X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S036030160903510X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,12,11]],"date-time":"2018-12-11T17:29:21Z","timestamp":1544549361000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S036030160903510X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,1]]},"references-count":12,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2011,1]]}},"alternative-id":["S036030160903510X"],"URL":"https:\/\/doi.org\/10.1016\/j.ijrobp.2009.10.043","relation":{},"ISSN":["0360-3016"],"issn-type":[{"value":"0360-3016","type":"print"}],"subject":[],"published":{"date-parts":[[2011,1]]}}}