{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T13:53:39Z","timestamp":1773323619686,"version":"3.50.1"},"reference-count":28,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2011,9,1]],"date-time":"2011-09-01T00:00:00Z","timestamp":1314835200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["International Journal of Radiation Oncology*Biology*Physics"],"published-print":{"date-parts":[[2011,9]]},"DOI":"10.1016\/j.ijrobp.2010.04.068","type":"journal-article","created":{"date-parts":[[2010,8,22]],"date-time":"2010-08-22T08:49:54Z","timestamp":1282466994000},"page":"140-149","source":"Crossref","is-referenced-by-count":9,"title":["Outcomes of Postoperative Simultaneous Modulated Accelerated Radiotherapy for Head-and-Neck Squamous Cell Carcinoma"],"prefix":"10.1016","volume":"81","author":[{"given":"Sung Ho","family":"Moon","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuh-Seog","family":"Jung","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jun Sun","family":"Ryu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sung Weon","family":"Choi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joo Yong","family":"Park","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tak","family":"Yun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sang Hyun","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kwan Ho","family":"Cho","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ijrobp.2010.04.068_bib1","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/S0360-3016(00)00663-5","article-title":"A Radiation Therapy Oncology Group (RTOG) phase III randomized study to compare hyperfractionation and two variants of accelerated fractionation to standard fractionation radiotherapy for head and neck squamous cell carcinomas: First report of RTOG 9003","volume":"48","author":"Fu","year":"2000","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2010.04.068_bib2","doi-asserted-by":"crossref","first-page":"1937","DOI":"10.1056\/NEJMoa032646","article-title":"Postoperative concurrent radiotherapy and chemotherapy for high-risk squamous-cell carcinoma of the head and neck","volume":"350","author":"Cooper","year":"2004","journal-title":"N Engl J Med"},{"key":"10.1016\/j.ijrobp.2010.04.068_bib3","doi-asserted-by":"crossref","first-page":"1945","DOI":"10.1056\/NEJMoa032641","article-title":"Postoperative irradiation with or without concomitant chemotherapy for locally advanced head and neck cancer","volume":"350","author":"Bernier","year":"2004","journal-title":"N Engl J Med"},{"key":"10.1016\/j.ijrobp.2010.04.068_bib4","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1002\/hed.20279","article-title":"Defining risk levels in locally advanced head and neck cancers: A comparative analysis of concurrent postoperative radiation plus chemotherapy trials of the EORTC (#22931) and RTOG (# 9501)","volume":"27","author":"Bernier","year":"2005","journal-title":"Head Neck"},{"key":"10.1016\/j.ijrobp.2010.04.068_bib5","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1002\/hed.20667","article-title":"SMART (simultaneous modulated accelerated radiotherapy) for locally advanced nasopharyngeal carcinomas","volume":"30","author":"Koom","year":"2008","journal-title":"Head Neck"},{"key":"10.1016\/j.ijrobp.2010.04.068_bib6","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1007\/s00066-007-1698-x","article-title":"Simultaneous integrated boost (SIB) for nasopharynx cancer with helical tomotherapy. A planning study","volume":"183","author":"Fiorino","year":"2007","journal-title":"Strahlenther Onkol"},{"key":"10.1016\/j.ijrobp.2010.04.068_bib7","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1016\/j.radonc.2007.01.008","article-title":"A dosimetric comparison of non-coplanar IMRT versus Helical Tomotherapy for nasal cavity and paranasal sinus cancer","volume":"82","author":"Sheng","year":"2007","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.ijrobp.2010.04.068_bib8","doi-asserted-by":"crossref","first-page":"917","DOI":"10.1016\/j.ijrobp.2006.02.038","article-title":"Intensity-modulated radiation therapy (IMRT) dosimetry of the head and neck: A comparison of treatment plans using linear accelerator-based IMRT and helical tomotherapy","volume":"65","author":"Sheng","year":"2006","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2010.04.068_bib9","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1016\/j.radonc.2006.02.009","article-title":"Significant improvement in normal tissue sparing and target coverage for head and neck cancer by means of helical tomotherapy","volume":"78","author":"Fiorino","year":"2006","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.ijrobp.2010.04.068_bib10","doi-asserted-by":"crossref","unstructured":"Orlandi E PE, Pignoli E, et al. Radiobiolobical basis and clinical results of the simultaneous integrated boost (SIB) in intensity modulated radiotherapy (IMRT) for head and neck cancer: A review. Crit Rev Oncol Hematol 2010;73:111\u2013125.","DOI":"10.1016\/j.critrevonc.2009.03.003"},{"key":"10.1016\/j.ijrobp.2010.04.068_bib11","doi-asserted-by":"crossref","first-page":"1096","DOI":"10.1016\/j.ijrobp.2008.05.024","article-title":"Intensity-modulated radiotherapy in postoperative treatment of oral cavity cancers","volume":"73","author":"Gomez","year":"2009","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2010.04.068_bib12","doi-asserted-by":"crossref","first-page":"1480","DOI":"10.1016\/S0360-3016(03)01569-4","article-title":"Assessment of different IMRT boost delivery methods on target coverage and normal-tissue sparing","volume":"57","author":"Dogan","year":"2003","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2010.04.068_bib13","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/S0167-8140(02)00326-2","article-title":"Comparative analysis of intensity modulation inverse planning modules of three commercial treatment planning systems applied to head and neck tumour model","volume":"66","author":"Fogliata","year":"2003","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.ijrobp.2010.04.068_bib14","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1016\/S0360-3016(99)00438-1","article-title":"Radiobiological considerations in the design of fractionation strategies for intensity-modulated radiation therapy of head and neck cancers","volume":"46","author":"Mohan","year":"2000","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2010.04.068_bib15","doi-asserted-by":"crossref","first-page":"1332","DOI":"10.1016\/j.ijrobp.2006.11.030","article-title":"The failure patterns of oral cavity squamous cell carcinoma after intensity-modulated radiotherapy-the university of iowa experience","volume":"67","author":"Yao","year":"2007","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2010.04.068_bib16","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1016\/j.ijrobp.2005.02.025","article-title":"Intensity-modulated radiation treatment for head-and-neck squamous cell carcinoma\u2014the University of Iowa experience","volume":"63","author":"Yao","year":"2005","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2010.04.068_bib17","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.ijrobp.2003.08.004","article-title":"Intensity-modulated radiation therapy for oropharyngeal carcinoma: Impact of tumor volume","volume":"59","author":"Chao","year":"2004","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2010.04.068_bib18","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/j.ijrobp.2003.10.032","article-title":"Recurrences near base of skull after IMRT for head-and-neck cancer: Implications for target delineation in high neck and for parotid gland sparing","volume":"59","author":"Eisbruch","year":"2004","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2010.04.068_bib19","first-page":"497","article-title":"Intensity-modulated chemoradiation for treatment of stage III and IV oropharyngeal carcinoma","volume":"113","author":"Huang","year":"2008","journal-title":"The University of California\u2013San Francisco experience. Cancer"},{"key":"10.1016\/j.ijrobp.2010.04.068_bib20","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1186\/1748-717X-2-16","article-title":"IMRT in oral cavity cancer","volume":"2","author":"Studer","year":"2007","journal-title":"Radiat Oncol"},{"key":"10.1016\/j.ijrobp.2010.04.068_bib21","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1002\/hed.2880120604","article-title":"Postoperative radiotherapy for oral cavity cancers: Impact of anatomic subsite on treatment outcome","volume":"12","author":"Zelefsky","year":"1990","journal-title":"Head Neck"},{"key":"10.1016\/j.ijrobp.2010.04.068_bib22","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1002\/cncr.23183","article-title":"Poor prognosis in patients with stage I and II oral tongue squamous cell carcinoma","volume":"112","author":"Rusthoven","year":"2008","journal-title":"Cancer"},{"key":"10.1016\/j.ijrobp.2010.04.068_bib23","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1016\/j.ijrobp.2005.03.006","article-title":"Intensity-modulated radiation therapy for the treatment of oropharyngeal carcinoma: The Memorial Sloan-Kettering Cancer Center experience","volume":"64","author":"de Arruda","year":"2006","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2010.04.068_bib24","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1016\/j.ijrobp.2007.03.013","article-title":"Concurrent chemotherapy and intensity-modulated radiotherapy for locoregionally advanced laryngeal and hypopharyngeal cancers","volume":"69","author":"Lee","year":"2007","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2010.04.068_bib25","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1016\/j.otohns.2006.10.044","article-title":"Accelerated radiotherapy with simultaneous integrated boost fractionation and intensity-modulated radiotherapy for advanced head and neck cancer","volume":"136","author":"Schwartz","year":"2007","journal-title":"Otolaryngol Head Neck Surg"},{"key":"10.1016\/j.ijrobp.2010.04.068_bib26","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1186\/1748-717X-1-7","article-title":"IMRT using simultaneously integrated boost (SIB) in head and neck cancer patients","volume":"1","author":"Studer","year":"2006","journal-title":"Radiat Oncol"},{"key":"10.1016\/j.ijrobp.2010.04.068_bib27","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.amjoto.2006.12.002","article-title":"Frequency of esophageal stenosis after simultaneous modulated accelerated radiation therapy and chemotherapy for head and neck cancer","volume":"29","author":"Lawson","year":"2008","journal-title":"Am J Otolaryngol"},{"key":"10.1016\/j.ijrobp.2010.04.068_bib28","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1002\/hed.20694","article-title":"Concurrent platinum-based chemotherapy and simultaneous modulated accelerated radiation therapy for locally advanced squamous cell carcinoma of the tongue base","volume":"30","author":"Lawson","year":"2008","journal-title":"Head Neck"}],"container-title":["International Journal of Radiation Oncology*Biology*Physics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0360301610006851?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0360301610006851?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,6,2]],"date-time":"2019-06-02T05:53:21Z","timestamp":1559454801000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0360301610006851"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,9]]},"references-count":28,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2011,9]]}},"alternative-id":["S0360301610006851"],"URL":"https:\/\/doi.org\/10.1016\/j.ijrobp.2010.04.068","relation":{},"ISSN":["0360-3016"],"issn-type":[{"value":"0360-3016","type":"print"}],"subject":[],"published":{"date-parts":[[2011,9]]}}}