{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T10:52:08Z","timestamp":1779879128164,"version":"3.53.1"},"reference-count":31,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2012,7,1]],"date-time":"2012-07-01T00:00:00Z","timestamp":1341100800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["International Journal of Radiation Oncology*Biology*Physics"],"published-print":{"date-parts":[[2012,7]]},"DOI":"10.1016\/j.ijrobp.2011.07.041","type":"journal-article","created":{"date-parts":[[2011,12,7]],"date-time":"2011-12-07T13:35:19Z","timestamp":1323264919000},"page":"887-894","source":"Crossref","is-referenced-by-count":127,"title":["Radioembolization for Neuroendocrine Liver Metastases: Safety, Imaging, and Long-Term Outcomes"],"prefix":"10.1016","volume":"83","author":[{"given":"Khairuddin","family":"Memon","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert J.","family":"Lewandowski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary F.","family":"Mulcahy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahsun","family":"Riaz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert K.","family":"Ryu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kent T.","family":"Sato","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ramona","family":"Gupta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"Nikolaidis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank H.","family":"Miller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vahid","family":"Yaghmai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vanessa L.","family":"Gates","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bassel","family":"Atassi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven","family":"Newman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Reed A.","family":"Omary","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"3rd","given":"Al B.","family":"Benson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Riad","family":"Salem","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ijrobp.2011.07.041_bib1","doi-asserted-by":"crossref","first-page":"712","DOI":"10.6004\/jnccn.2009.0050","article-title":"NCCN clinical practice guidelines in oncology: Neuroendocrine tumors","volume":"7","author":"Clark","year":"2009","journal-title":"J Natl Compr Canc Netw"},{"key":"10.1016\/j.ijrobp.2011.07.041_bib2","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1097\/COC.0b013e31815e4557","article-title":"Radioembolization for unresectable neuroendocrine hepatic metastases using resin 90Y-microspheres: Early results in 148 patients","volume":"31","author":"Kennedy","year":"2008","journal-title":"Am J Clin Oncol"},{"key":"10.1016\/j.ijrobp.2011.07.041_bib3","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1056\/NEJM199202203260804","article-title":"Streptozocin-doxorubicin, streptozocin-fluorouracil or chlorozotocin in the treatment of advanced islet-cell carcinoma","volume":"326","author":"Moertel","year":"1992","journal-title":"N Engl J Med"},{"key":"10.1016\/j.ijrobp.2011.07.041_bib4","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1056\/NEJMoa1003825","article-title":"Sunitinib malate for the treatment of pancreatic neuroendocrine tumors","volume":"364","author":"Raymond","year":"2011","journal-title":"N Engl J Med"},{"key":"10.1016\/j.ijrobp.2011.07.041_bib5","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1056\/NEJMoa1009290","article-title":"Everolimus for advanced pancreatic neuroendocrine tumors","volume":"364","author":"Yao","year":"2011","journal-title":"N Engl J Med"},{"key":"10.1016\/j.ijrobp.2011.07.041_bib6","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1016\/j.bpg.2005.04.003","article-title":"Surgical treatment of neuroendocrine metastases","volume":"19","author":"Norton","year":"2005","journal-title":"Best Pract Res Clin Gastroenterol"},{"key":"10.1016\/j.ijrobp.2011.07.041_bib7","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1016\/j.gassur.2003.11.010","article-title":"Liver transplantation for neuroendocrine tumors","volume":"8","author":"Florman","year":"2004","journal-title":"J Gastrointest Surg"},{"key":"10.1016\/j.ijrobp.2011.07.041_bib8","doi-asserted-by":"crossref","unstructured":"Dong XD, Carr BI. Hepatic artery chemoembolization for the treatment of liver metastases from neuroendocrine tumors: A long-term follow-up in 123 patients. Med Oncol. In press.","DOI":"10.1007\/s12032-010-9750-6"},{"key":"10.1016\/j.ijrobp.2011.07.041_bib9","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1016\/j.jvir.2007.04.018","article-title":"Chemoembolization and bland embolization of neuroendocrine tumor metastases to the liver","volume":"18","author":"Ruutiainen","year":"2007","journal-title":"J Vasc Interv Radiol"},{"key":"10.1016\/j.ijrobp.2011.07.041_bib10","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1007\/s00270-007-9064-z","article-title":"Radioembolization with (90)y microspheres: Angiographic and technical considerations","volume":"30","author":"Lewandowski","year":"2007","journal-title":"Cardiovasc Intervent Radiol"},{"key":"10.1016\/j.ijrobp.2011.07.041_bib11","doi-asserted-by":"crossref","first-page":"S223","DOI":"10.1016\/S1051-0443(07)61790-4","article-title":"Yttrium-90 microspheres: Radiation therapy for unresectable liver cancer","volume":"13","author":"Salem","year":"2002","journal-title":"J Vasc Interv Radiol"},{"key":"10.1016\/j.ijrobp.2011.07.041_bib12","doi-asserted-by":"crossref","first-page":"1251","DOI":"10.1097\/01.RVI.0000233785.75257.9A","article-title":"Radioembolization with 90yttrium microspheres: A state-of-the-art brachytherapy treatment for primary and secondary liver malignancies. Part 1: Technical and methodologic considerations","volume":"17","author":"Salem","year":"2006","journal-title":"J Vasc Interv Radiol"},{"key":"10.1016\/j.ijrobp.2011.07.041_bib13","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/j.jvir.2010.10.029","article-title":"Research reporting standards for radioembolization of hepatic malignancies","volume":"22","author":"Salem","year":"2011","journal-title":"J Vasc Interv Radiol"},{"key":"10.1016\/j.ijrobp.2011.07.041_bib14","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1053\/j.gastro.2010.10.049","article-title":"Radioembolization results in longer time-to-progression and reduced toxicity compared with chemoembolization in patients with hepatocellular carcinoma","volume":"140","author":"Salem","year":"2011","journal-title":"Gastroenterology"},{"key":"10.1016\/j.ijrobp.2011.07.041_bib15","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1016\/j.jhep.2010.10.004","article-title":"Role of the EASL, RECIST, and WHO response guidelines alone or in combination for hepatocellular carcinoma: Radiologic\u2013pathologic correlation","volume":"54","author":"Riaz","year":"2011","journal-title":"J Hepatol"},{"key":"10.1016\/j.ijrobp.2011.07.041_bib16","doi-asserted-by":"crossref","first-page":"1062","DOI":"10.1001\/jama.2010.262","article-title":"Imaging response in the primary index lesion and clinical outcomes following transarterial locoregional therapy for hepatocellular carcinoma","volume":"303","author":"Riaz","year":"2010","journal-title":"JAMA"},{"key":"10.1016\/j.ijrobp.2011.07.041_bib17","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1053\/j.gastro.2009.09.006","article-title":"Radioembolization for hepatocellular carcinoma using yttrium-90 microspheres: A comprehensive report of long-term outcomes","volume":"138","author":"Salem","year":"2010","journal-title":"Gastroenterology"},{"key":"10.1016\/j.ijrobp.2011.07.041_bib18","first-page":"559","article-title":"[The problem of multiple testing and solutions for genome-wide studies]","volume":"146","author":"Gyorffy","year":"2005","journal-title":"Orv Hetil"},{"key":"10.1016\/j.ijrobp.2011.07.041_bib19","doi-asserted-by":"crossref","first-page":"815","DOI":"10.1097\/00000658-199906000-00008","article-title":"Prognosis and survival in patients with gastrointestinal tract carcinoid tumors","volume":"229","author":"Shebani","year":"1999","journal-title":"Ann Surg"},{"key":"10.1016\/j.ijrobp.2011.07.041_bib20","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1677\/ERC-06-0061","article-title":"Gastrointestinal neuroendocrine tumors: A role for targeted therapies?","volume":"14","author":"Kulke","year":"2007","journal-title":"Endocr Relat Cancer"},{"key":"10.1016\/j.ijrobp.2011.07.041_bib21","doi-asserted-by":"crossref","first-page":"1029","DOI":"10.1097\/SLA.0b013e3181728a45","article-title":"90Y Radioembolization for metastatic neuroendocrine liver tumors: Preliminary results from a multi-institutional experience","volume":"247","author":"Rhee","year":"2008","journal-title":"Ann Surg"},{"key":"10.1016\/j.ijrobp.2011.07.041_bib22","doi-asserted-by":"crossref","first-page":"910","DOI":"10.1097\/SLA.0b013e3181d3d24a","article-title":"Factors predicting response and survival after yttrium-90 radioembolization of unresectable neuroendocrine tumor liver metastases: A critical appraisal of 48 cases","volume":"251","author":"Saxena","year":"2010","journal-title":"Ann Surg"},{"key":"10.1016\/j.ijrobp.2011.07.041_bib23","first-page":"969","article-title":"The blood supply of neoplasms in the liver","volume":"30","author":"Breedis","year":"1954","journal-title":"Am J Pathol"},{"key":"10.1016\/j.ijrobp.2011.07.041_bib24","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.ijrobp.2006.11.060","article-title":"Recommendations for radioembolization of hepatic malignancies using yttrium-90 microsphere brachytherapy: A consensus panel report from the radioembolization brachytherapy oncology consortium","volume":"68","author":"Kennedy","year":"2007","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2011.07.041_bib25","doi-asserted-by":"crossref","first-page":"921","DOI":"10.1002\/cncr.23685","article-title":"Radioembolization with selective internal radiation microspheres for neuroendocrine liver metastases","volume":"113","author":"King","year":"2008","journal-title":"Cancer"},{"key":"10.1016\/j.ijrobp.2011.07.041_bib26","doi-asserted-by":"crossref","first-page":"526","DOI":"10.1053\/j.gastro.2011.04.054","article-title":"Radiographic response to locoregional therapy in hepatocellular carcinoma predicts patient survival times","volume":"141","author":"Memon","year":"2011","journal-title":"Gastroenterology"},{"key":"10.1016\/j.ijrobp.2011.07.041_bib27","doi-asserted-by":"crossref","first-page":"855","DOI":"10.1016\/j.jvir.2008.01.030","article-title":"Transarterial chemoembolization of liver metastases from well differentiated gastroenteropancreatic endocrine tumors with doxorubicin-eluting beads: Preliminary results","volume":"19","author":"de Baere","year":"2008","journal-title":"J Vasc Interv Radiol"},{"key":"10.1016\/j.ijrobp.2011.07.041_bib28","doi-asserted-by":"crossref","first-page":"941","DOI":"10.2214\/AJR.08.1879","article-title":"Liver metastases of neuroendocrine tumors: Treatment with hepatic transarterial chemotherapy using two therapeutic protocols","volume":"193","author":"Vogl","year":"2009","journal-title":"AJR Am J Roentgenol"},{"key":"10.1016\/j.ijrobp.2011.07.041_bib29","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1177\/107327480601300110","article-title":"Selective hepatic artery embolization for treatment of patients with metastatic carcinoid and pancreatic endocrine tumors","volume":"13","author":"Strosberg","year":"2006","journal-title":"Cancer Control"},{"key":"10.1016\/j.ijrobp.2011.07.041_bib30","doi-asserted-by":"crossref","first-page":"1379","DOI":"10.2214\/ajr.180.5.1801379","article-title":"Permanent transarterial embolization of neuroendocrine metastases of the liver using cyanoacrylate and lipiodol: Assessment of mid- and long-term results","volume":"180","author":"Loewe","year":"2003","journal-title":"AJR Am J Roentgenol"},{"key":"10.1016\/j.ijrobp.2011.07.041_bib31","doi-asserted-by":"crossref","first-page":"2293","DOI":"10.1002\/(SICI)1097-0142(19981201)83:11<2293::AID-CNCR8>3.0.CO;2-E","article-title":"Liver embolizations of patients with malignant neuroendocrine gastrointestinal tumors","volume":"83","author":"Eriksson","year":"1998","journal-title":"Cancer"}],"container-title":["International Journal of Radiation Oncology*Biology*Physics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0360301611031336?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0360301611031336?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,6,20]],"date-time":"2019-06-20T09:50:12Z","timestamp":1561024212000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0360301611031336"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,7]]},"references-count":31,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2012,7]]}},"alternative-id":["S0360301611031336"],"URL":"https:\/\/doi.org\/10.1016\/j.ijrobp.2011.07.041","relation":{},"ISSN":["0360-3016"],"issn-type":[{"value":"0360-3016","type":"print"}],"subject":[],"published":{"date-parts":[[2012,7]]}}}