{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T18:04:55Z","timestamp":1792001095632,"version":"4.4.0"},"reference-count":17,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2012,8,1]],"date-time":"2012-08-01T00:00:00Z","timestamp":1343779200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["International Journal of Radiation Oncology*Biology*Physics"],"published-print":{"date-parts":[[2012,8]]},"DOI":"10.1016\/j.ijrobp.2011.10.074","type":"journal-article","created":{"date-parts":[[2012,7,7]],"date-time":"2012-07-07T03:26:14Z","timestamp":1341631574000},"page":"1609-1616","source":"Crossref","is-referenced-by-count":23,"title":["Metabolic Imaging Biomarkers of Postradiotherapy Xerostomia"],"prefix":"10.1016","volume":"83","author":[{"given":"Blake","family":"Cannon","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David L.","family":"Schwartz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lei","family":"Dong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ijrobp.2011.10.074_bib1","doi-asserted-by":"crossref","first-page":"3282","DOI":"10.1200\/JCO.2006.06.6068","article-title":"Positron emission tomography as an imaging biomarker","volume":"24","author":"Weber","year":"2006","journal-title":"J\u00a0Clin Oncol"},{"key":"10.1016\/j.ijrobp.2011.10.074_bib2","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1016\/S0360-3016(01)01512-7","article-title":"Xerostomia and its predictors following parotid-sparing irradiation of head-and-neck cancer","volume":"50","author":"Eisbruch","year":"2001","journal-title":"Int J\u00a0Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2011.10.074_bib3","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1016\/j.ijrobp.2006.05.002","article-title":"Grading xerostomia by physicians or by patients after intensity-modulated radiotherapy of head-and-neck cancer","volume":"66","author":"Meirovitz","year":"2006","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2011.10.074_bib4","doi-asserted-by":"crossref","first-page":"1451","DOI":"10.1016\/j.ijrobp.2003.09.021","article-title":"Scintigraphic assessment of early and late parotid gland function after radiotherapy for head-and-neck cancer: A prospective study of dose-volume response relationships","volume":"58","author":"Roesink","year":"2004","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2011.10.074_bib5","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1016\/j.radonc.2008.02.017","article-title":"Scintigraphy in prediction of the salivary gland function after gland-sparing intensity modulated radiation therapy for head and neck cancer","volume":"87","author":"Tenhunen","year":"2008","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.ijrobp.2011.10.074_bib6","doi-asserted-by":"crossref","first-page":"2509","DOI":"10.1200\/JCO.2008.19.3300","article-title":"Prospective risk-adjusted [18F]fluorodeoxyglucose positron emission tomography and computed tomography assessment of radiation response in head and neck cancer","volume":"27","author":"Moeller","year":"2009","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.ijrobp.2011.10.074_bib7","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1016\/j.ijrobp.2009.08.063","article-title":"Prospective imaging assessment of mortality risk after head-and-neck radiotherapy","volume":"78","author":"Moeller","year":"2010","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2011.10.074_bib8","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1016\/j.radonc.2009.09.008","article-title":"Delineation guidelines for organs at risk involved in radiation-induced salivary dysfunction and xerostomia","volume":"93","author":"van de Water","year":"2009","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.ijrobp.2011.10.074_bib9","doi-asserted-by":"crossref","first-page":"2887","DOI":"10.1088\/0031-9155\/50\/12\/011","article-title":"Validation of an accelerated \u201cdemons\u201d algorithm for deformable image registration in radiation therapy","volume":"50","author":"Wang","year":"2005","journal-title":"Phys Med Biol"},{"key":"10.1016\/j.ijrobp.2011.10.074_bib10","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1016\/j.ijrobp.2003.12.033","article-title":"Dose-volume response analyses of late rectal bleeding after radiotherapy for prostate cancer","volume":"59","author":"Tucker","year":"2004","journal-title":"Int J\u00a0Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2011.10.074_bib11","doi-asserted-by":"crossref","first-page":"1043","DOI":"10.1016\/0360-3016(95)00059-8","article-title":"Late effects toxicity scoring: The SOMA scale","volume":"31","author":"Pavy","year":"1995","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2011.10.074_bib12","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1016\/j.ijrobp.2005.06.042","article-title":"Secondary radiation damage as the main cause for unexpected volume effects: A histopathologic study of the parotid gland","volume":"64","author":"Konings","year":"2006","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2011.10.074_bib13","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1097\/00000478-198104000-00008","article-title":"Radiation injury in surgical pathology. Part III. Salivary glands, pancreas and skin","volume":"5","author":"Fajardo","year":"1981","journal-title":"Am J Surg Pathol"},{"key":"10.1016\/j.ijrobp.2011.10.074_bib14","doi-asserted-by":"crossref","first-page":"960","DOI":"10.1016\/j.ijrobp.2003.12.024","article-title":"Quantification of volumetric and geometric changes occurring during fractionated radiotherapy for head-and-neck cancer using an integrated CT\/linear accelerator system","volume":"59","author":"Barker","year":"2004","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2011.10.074_bib15","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1093\/ageing\/28.6.557","article-title":"Effect of age on variability of parotid salivary gland flow rates over time","volume":"28","author":"Fischer","year":"1999","journal-title":"Age Ageing"},{"key":"10.1016\/j.ijrobp.2011.10.074_bib16","doi-asserted-by":"crossref","first-page":"M285","DOI":"10.1093\/gerona\/50A.5.M285","article-title":"Longitudinal analysis of parotid and submandibular salivary flow rates in healthy, different-aged adults","volume":"50","author":"Ship","year":"1995","journal-title":"J\u00a0Gerontol A Biol Sci Med Sci"},{"key":"10.1016\/j.ijrobp.2011.10.074_bib17","unstructured":"Roach MC, Turkington TG, Higgins KA, et\u00a0al. FDG-PET assessment of the effect of head and neck radiotherapy on parotid gland glucose metabolism. Int J Radiat Oncol Biol Phys [Epub Oct 27, 2010]."}],"container-title":["International Journal of Radiation Oncology*Biology*Physics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0360301611034821?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0360301611034821?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,11,22]],"date-time":"2018-11-22T08:52:44Z","timestamp":1542876764000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0360301611034821"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,8]]},"references-count":17,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2012,8]]}},"alternative-id":["S0360301611034821"],"URL":"https:\/\/doi.org\/10.1016\/j.ijrobp.2011.10.074","relation":{},"ISSN":["0360-3016"],"issn-type":[{"value":"0360-3016","type":"print"}],"subject":[],"published":{"date-parts":[[2012,8]]}}}