{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T07:02:49Z","timestamp":1761807769761},"reference-count":72,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2012,12,1]],"date-time":"2012-12-01T00:00:00Z","timestamp":1354320000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["International Journal of Radiation Oncology*Biology*Physics"],"published-print":{"date-parts":[[2012,12]]},"DOI":"10.1016\/j.ijrobp.2012.03.018","type":"journal-article","created":{"date-parts":[[2012,11,9]],"date-time":"2012-11-09T07:16:59Z","timestamp":1352445419000},"page":"1048-1057","source":"Crossref","is-referenced-by-count":9,"title":["Surgical Management of Early-Stage Non-small Cell Lung Carcinoma and the Present and Future Roles of Adjuvant Therapy: A Review for the Radiation Oncologist"],"prefix":"10.1016","volume":"84","clinical-trial-number":[{"clinical-trial-number":"nct00107172","registry":"10.18810\/clinical-trials-gov"},{"clinical-trial-number":"nct00775385","registry":"10.18810\/clinical-trials-gov"},{"clinical-trial-number":"nct01102517","registry":"10.18810\/clinical-trials-gov"}],"author":[{"given":"Laura","family":"Medford-Davis","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Malcom","family":"DeCamp","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abram","family":"Recht","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John","family":"Flickinger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chandra P.","family":"Belani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John","family":"Varlotto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"4","key":"10.1016\/j.ijrobp.2012.03.018_bib1","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1002\/cncr.23985","article-title":"Extent of lymphadenectomy and outcome for patients with stage I nonsmall cell lung cancer","volume":"115","author":"Varlotto","year":"2009","journal-title":"Cancer"},{"key":"10.1016\/j.ijrobp.2012.03.018_bib2","unstructured":"National Cancer Center Network (2010) NCCN Clinical Practice Guidelines in Oncology (National Cancer Center Network, Fort Washington, PA) http:\/\/www.nccn.org\/professionals\/physician_gls\/f_guidelines.asp. Accessed 27 Nov\u00a02011."},{"key":"10.1016\/j.ijrobp.2012.03.018_bib3","doi-asserted-by":"crossref","first-page":"710","DOI":"10.1136\/thx.2005.056481","article-title":"Survival after resection for primary lung cancer: a population based study of 3211 resected patients","volume":"61","author":"Strand","year":"2006","journal-title":"Thorax"},{"key":"10.1016\/j.ijrobp.2012.03.018_bib4","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1016\/j.athoracsur.2006.02.029","article-title":"Outcomes of sublobar resection versus lobectomy for stage I non-small cell lung cancer: a 13-year analysis","volume":"82","author":"El-Sherif","year":"2006","journal-title":"Ann Thorac Surg"},{"key":"10.1016\/j.ijrobp.2012.03.018_bib5","doi-asserted-by":"crossref","first-page":"1759","DOI":"10.1016\/S0003-4975(00)02609-6","article-title":"Prognosis and survival after resection for bronchogenic carcinoma based on the 1997 TNM-staging classification: the Japanese experience","volume":"71","author":"Naruke","year":"2001","journal-title":"Ann Thorac Surg"},{"key":"10.1016\/j.ijrobp.2012.03.018_bib6","doi-asserted-by":"crossref","first-page":"1710","DOI":"10.1378\/chest.111.6.1710","article-title":"Revisions in the international system for staging lung cancer","volume":"111","author":"Mountain","year":"1997","journal-title":"Chest"},{"key":"10.1016\/j.ijrobp.2012.03.018_bib7","doi-asserted-by":"crossref","first-page":"694","DOI":"10.1097\/JTO.0b013e31812d05d5","article-title":"The IASLC Lung Cancer Staging Project: validation of the proposals for revision of the T, N, and M descriptors and consequent stage groupings in the forthcoming (seventh) edition of the TNM classification of malignant tumours","volume":"2","author":"Groome","year":"2007","journal-title":"J\u00a0Thorac Oncol"},{"key":"10.1016\/j.ijrobp.2012.03.018_bib8","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1056\/NEJMra035536","article-title":"Drug therapy: multidisciplinary management of lung cancer","volume":"350","author":"Spira","year":"2004","journal-title":"N Engl J Med"},{"key":"10.1016\/j.ijrobp.2012.03.018_bib9","doi-asserted-by":"crossref","first-page":"4404","DOI":"10.1200\/JCO.2010.31.0144","article-title":"Non-small-cell lung cancer mRNA expression signature predicting response to adjuvant chemotherapy","volume":"28","author":"Xie","year":"2010","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.ijrobp.2012.03.018_bib10","doi-asserted-by":"crossref","first-page":"850","DOI":"10.1016\/j.jtcvs.2007.03.044","article-title":"Factors predicting poor survival after resection of stage IA non-small cell lung cancer","volume":"134","author":"Chang","year":"2007","journal-title":"J\u00a0Thorac Cardiovasc Surg"},{"key":"10.1016\/j.ijrobp.2012.03.018_bib11","doi-asserted-by":"crossref","first-page":"5506","DOI":"10.1200\/JCO.2007.14.1226","article-title":"Cancer Care Ontario and American Society of Clinical Oncology adjuvant chemotherapy and adjuvant radiation therapy for stages I-IIIA resectable non small-cell lung cancer guideline","volume":"25","author":"Pisters","year":"2007","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.ijrobp.2012.03.018_bib12","doi-asserted-by":"crossref","first-page":"792","DOI":"10.1097\/JTO.0b013e3181a7716e","article-title":"The international association for the study of lung cancer staging project: prognostic factors and pathologic TNM stage in surgically managed non-small cell lung cancer","volume":"4","author":"Chansky","year":"2009","journal-title":"J Thorac Oncol"},{"key":"10.1016\/j.ijrobp.2012.03.018_bib13","doi-asserted-by":"crossref","first-page":"1267","DOI":"10.1016\/S0140-6736(10)60059-1","article-title":"Adjuvant chemotherapy, with or without postoperative radiotherapy, in operable non-small-cell lung cancer: two meta-analyses of individual patient data","volume":"375","year":"2010","journal-title":"Lancet"},{"key":"10.1016\/j.ijrobp.2012.03.018_bib14","first-page":"257","article-title":"Postoperative radiotherapy in non-small-cell lung cancer: systematic review and meta-analysis of individual patient data from nine randomized controlled trials","volume":"25","year":"1998","journal-title":"Lancet"},{"key":"10.1016\/j.ijrobp.2012.03.018_bib15","doi-asserted-by":"crossref","first-page":"999","DOI":"10.1016\/j.athoracsur.2004.04.007","article-title":"Recent results of postoperative mortality for surgical resections in lung cancer","volume":"78","author":"Watanabe","year":"2004","journal-title":"Ann Thorac Surg"},{"key":"10.1016\/j.ijrobp.2012.03.018_bib16","doi-asserted-by":"crossref","first-page":"814","DOI":"10.1016\/S0022-5223(00)70018-3","article-title":"Survival related to lymph node involvement in lung cancer after sleeve lobectomy compared with pneumonectomy","volume":"119","author":"Okada","year":"2000","journal-title":"J Thorac Cardiovasc Surg"},{"key":"10.1016\/j.ijrobp.2012.03.018_bib17","doi-asserted-by":"crossref","first-page":"1059","DOI":"10.1002\/cncr.24133","article-title":"Factors associated with local and distant recurrence and survival in patients with resected non-small cell lung cancer","volume":"115","author":"Varlotto","year":"2009","journal-title":"Cancer"},{"key":"10.1016\/j.ijrobp.2012.03.018_bib18","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1016\/0003-4975(95)00537-U","article-title":"Randomized trial of lobectomy versus limited resection for T1 N0 non-small cell lung cancer. Lung Cancer Study Group","volume":"60","author":"Ginsberg","year":"1995","journal-title":"Ann Thorac Surg"},{"issue":"3 Suppl","key":"10.1016\/j.ijrobp.2012.03.018_bib19","doi-asserted-by":"crossref","first-page":"S62","DOI":"10.1016\/j.ijrobp.2009.07.160","article-title":"Preoperative identification of stage I non-small cell lung cancer patients at high risk for local recurrence following limited resection [Abstract]","volume":"75","author":"Medford-Davis","year":"2009","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2012.03.018_bib20","doi-asserted-by":"crossref","first-page":"956","DOI":"10.1016\/S0003-4975(00)02223-2","article-title":"Is segmentectomy with lymph node assessment an alternative to lobectomy for non-small cell lung cancer of 2 cm or smaller?","volume":"71","author":"Okada","year":"2001","journal-title":"Ann Thorac Surg"},{"key":"10.1016\/j.ijrobp.2012.03.018_bib21","doi-asserted-by":"crossref","first-page":"1033","DOI":"10.1038\/sj.bjc.6602414","article-title":"Survival following lobectomy vs limited resection for stage I lung cancer: a meta-analysis","volume":"92","author":"Nakamura","year":"2005","journal-title":"Br J Cancer"},{"key":"10.1016\/j.ijrobp.2012.03.018_bib22","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.jtcvs.2009.03.030","article-title":"Lobectomy by video-assisted thoracic surgery (VATS) versus thoracotomy for lung cancer","volume":"138","author":"Flores","year":"2009","journal-title":"J Thorac Cardiovasc Surg"},{"key":"10.1016\/j.ijrobp.2012.03.018_bib23","doi-asserted-by":"crossref","first-page":"976","DOI":"10.1016\/j.jtcvs.2009.11.059","article-title":"Video-assisted thoracic surgery versus open lobectomy for lung cancer: a secondary analysis of data from the American College of Surgeons Oncology Group Z0030 randomized clinical trial","volume":"139","author":"Scott","year":"2010","journal-title":"J Thorac Cardiovasc Surg"},{"key":"10.1016\/j.ijrobp.2012.03.018_bib24","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1007\/s002689910006","article-title":"Video-assisted thoracoscopic lobectomy achieves a satisfactory long-term prognosis in patients with clinical stage IA lung cancer","volume":"24","author":"Sugi","year":"2000","journal-title":"World J Surg"},{"key":"10.1016\/j.ijrobp.2012.03.018_bib25","doi-asserted-by":"crossref","first-page":"2553","DOI":"10.1200\/JCO.2008.18.2733","article-title":"Systematic review and meta-analysis of randomized and nonrandomized trials on safety and efficacy of video-assisted thoracic surgery lobectomy for early-stage non-small-cell lung cancer","volume":"27","author":"Yan","year":"2009","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.ijrobp.2012.03.018_bib26","doi-asserted-by":"crossref","first-page":"2008","DOI":"10.1016\/j.athoracsur.2008.07.009","article-title":"Surgery for early-stage non-small cell lung cancer: a systematic review of the video-assisted thoracoscopic surgery versus thoracotomy approaches to lobectomy","volume":"86","author":"Whitson","year":"2008","journal-title":"Ann Thorac Surg"},{"key":"10.1016\/j.ijrobp.2012.03.018_bib27","doi-asserted-by":"crossref","first-page":"1772","DOI":"10.1016\/S0003-4975(01)02520-6","article-title":"Nodal occult metastasis in patients with peripheral lung adenocarcinoma of 2.0 cm or less in diameter","volume":"71","author":"Wu","year":"2001","journal-title":"Ann Thorac Surg"},{"key":"10.1016\/j.ijrobp.2012.03.018_bib28","doi-asserted-by":"crossref","first-page":"4313","DOI":"10.1200\/JCO.2011.35.2500","article-title":"Occult metastases in lymph nodes predict survival in resectable non-small-cell lung cancer: report of the ACOSOG Z0040 trial","volume":"29","author":"Rusch","year":"2011","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.ijrobp.2012.03.018_bib29","doi-asserted-by":"crossref","DOI":"10.1002\/14651858.CD004699.pub2","article-title":"Surgery for local and locally advanced non-small cell lung cancer","volume":"1","author":"Manser","year":"2005","journal-title":"Cochrane Database of Systematic Reviews"},{"key":"10.1016\/j.ijrobp.2012.03.018_bib30","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0169-5002(01)00445-7","article-title":"A randomized trial of systematic nodal dissection in resectable non-small cell lung cancer","volume":"36","author":"Wu","year":"2002","journal-title":"Lung Cancer"},{"key":"10.1016\/j.ijrobp.2012.03.018_bib31","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1016\/j.jtcvs.2010.11.008","article-title":"Randomized trial of mediastinal lymph node sampling versus complete lymphadenectomy during pulmonary resection in the patient with N0 or N1 (less than hilar) non-small cell carcinoma: results of the American College of Surgery Oncology Group Z0030 trial","volume":"141","author":"Darling","year":"2011","journal-title":"J Thorac Cardiovasc Surg"},{"key":"10.1016\/j.ijrobp.2012.03.018_bib32","doi-asserted-by":"crossref","first-page":"1124","DOI":"10.1378\/chest.10-0859","article-title":"Number of lymph nodes harvested from a mediastinal lymphadenectomy","volume":"139","author":"Darling","year":"2011","journal-title":"Chest"},{"key":"10.1016\/j.ijrobp.2012.03.018_bib33","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1016\/j.ejcts.2004.12.035","article-title":"Does the extent of lymph node dissection influence outcome in patients with stage I non-small-cell lung cancer?","volume":"27","author":"Doddoli","year":"2005","journal-title":"Euro J Cardio Thorac Surg"},{"key":"10.1016\/j.ijrobp.2012.03.018_bib34","doi-asserted-by":"crossref","first-page":"965","DOI":"10.1016\/S0360-3016(98)00508-2","article-title":"Predictors of subclinical nodal involvement in clinical stages I and II non-small cell lung cancer","volume":"43","author":"Sawyer","year":"1999","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2012.03.018_bib35","doi-asserted-by":"crossref","first-page":"2051","DOI":"10.1016\/j.athoracsur.2005.06.071","article-title":"Patterns of surgical care of lung cancer patients","volume":"80","author":"Little","year":"2005","journal-title":"Ann Thorac Surg"},{"key":"10.1016\/j.ijrobp.2012.03.018_bib36","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1056\/NEJMoa031644","article-title":"Cisplatin-based adjuvant chemotherapy in patients with completely resected non-small-cell lung cancer","volume":"350","year":"2004","journal-title":"N Engl J Med"},{"key":"10.1016\/j.ijrobp.2012.03.018_bib37","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1016\/S1470-2045(06)70804-X","article-title":"Adjuvant vinorelbine plus cisplatin versus observation in patients with completely resected stage IB-IIIA non-small-cell lung cancer (Adjuvant Navelbine International Trialist Association [ANITA]): a randomized controlled trial","volume":"7","author":"Drouillard","year":"2006","journal-title":"Lancet"},{"key":"10.1016\/j.ijrobp.2012.03.018_bib38","doi-asserted-by":"crossref","first-page":"2589","DOI":"10.1056\/NEJMoa043623","article-title":"Vinorelbine plus cisplatin vs. observation in resected non-small-cell lung cancer","volume":"352","author":"Winton","year":"2005","journal-title":"N Engl J Med"},{"key":"10.1016\/j.ijrobp.2012.03.018_bib39","doi-asserted-by":"crossref","first-page":"5043","DOI":"10.1200\/JCO.2008.16.4855","article-title":"Adjuvant paclitaxel plus carboplatin compared with observation in stage IB non-small-cell lung cancer: CALGB 9633 with the Cancer and Leukemia Group B, Radiation Therapy Oncology Group, and North Central Cancer Treatment Group Study Groups","volume":"26","author":"Strauss","year":"2008","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.ijrobp.2012.03.018_bib40","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1200\/JCO.2009.23.2272","article-title":"Long-term results of the international adjuvant lung cancer trial evaluating adjuvant cisplatin-based chemotherapy in resected lung cancer","volume":"28","author":"Arriagada","year":"2010","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.ijrobp.2012.03.018_bib41","doi-asserted-by":"crossref","first-page":"3552","DOI":"10.1200\/JCO.2007.13.9030","article-title":"Lung adjuvant cisplatin evaluation: a pooled analysis by the LACE Collaborative Group","volume":"26","author":"Pignon","year":"2008","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.ijrobp.2012.03.018_bib42","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1200\/JCO.20.1.247","article-title":"Preoperative chemotherapy followed by surgery compared with primary surgery in resectable stage I (except T1N0), II, and IIIa non-small-cell lung cancer","volume":"20","author":"Depierre","year":"2002","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.ijrobp.2012.03.018_bib43","doi-asserted-by":"crossref","first-page":"1843","DOI":"10.1200\/JCO.2009.26.1685","article-title":"Surgery with or without preoperative paclitaxel and carboplatin in early-stage non-small-cell lung cancer: Southwest Oncology Group Trial S9900, an\u00a0intergroup, randomized, phase III trial","volume":"28","author":"Pisters","year":"2010","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.ijrobp.2012.03.018_bib44","first-page":"CD006157","article-title":"Chemotherapy and surgery versus surgery alone in non-small cell lung cancer","volume":"3","author":"Burdett","year":"2007","journal-title":"Cochrane Database of Systematic Reviews"},{"key":"10.1016\/j.ijrobp.2012.03.018_bib45","doi-asserted-by":"crossref","first-page":"3138","DOI":"10.1200\/JCO.2009.27.6204","article-title":"Preoperative chemotherapy plus surgery versus surgery plus adjuvant chemotherapy versus surgery alone in early-stage non-small-cell lung cancer","volume":"28","author":"Felip","year":"2010","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.ijrobp.2012.03.018_bib46","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1016\/S0140-6736(98)22030-7","article-title":"What now for postoperative radiotherapy for lung cancer?","volume":"25","author":"Munro","year":"1998","journal-title":"Lancet"},{"key":"10.1016\/j.ijrobp.2012.03.018_bib47","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1002\/(SICI)1097-0142(19990715)86:2<265::AID-CNCR10>3.0.CO;2-B","article-title":"A controlled study of postoperative radiotherapy for patients with completely resected nonsmall cell lung carcinoma. Groupe d'Etude et de Traitement des Cancers Bonchiques","volume":"86","author":"Dautzenberg","year":"1999","journal-title":"Cancer"},{"key":"10.1016\/j.ijrobp.2012.03.018_bib48","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/S0167-8140(01)00478-9","article-title":"Adjuvant radiotherapy in non-small cell lung cancer with pathological stage I: definitive results of a phase III randomized trial","volume":"62","author":"Trodella","year":"2002","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.ijrobp.2012.03.018_bib49","doi-asserted-by":"crossref","first-page":"954","DOI":"10.1378\/chest.112.4.954","article-title":"Postoperative radiotherapy in radically resected non-small cell lung cancer","volume":"112","author":"Mayer","year":"1997","journal-title":"Chest"},{"key":"10.1016\/j.ijrobp.2012.03.018_bib50","doi-asserted-by":"crossref","first-page":"1399","DOI":"10.1002\/(SICI)1097-0142(19971015)80:8<1399::AID-CNCR6>3.0.CO;2-A","article-title":"The impact of surgical adjuvant thoracic radiation therapy for non-small cell lung carcinoma with mediastinal nodal involvement","volume":"80","author":"Sawyer","year":"1997","journal-title":"Cancer"},{"key":"10.1016\/j.ijrobp.2012.03.018_bib51","doi-asserted-by":"crossref","first-page":"2998","DOI":"10.1200\/JCO.2005.04.6110","article-title":"Postoperative radiotherapy for stage II and III non-small-cell lung cancer using the surveillance, epidemiology, and end results database","volume":"24","author":"Lally","year":"2006","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.ijrobp.2012.03.018_bib52","doi-asserted-by":"crossref","first-page":"1377","DOI":"10.1056\/NEJM198611273152202","article-title":"Effects of postoperative mediastinal radiation on completely resected stage II and stage III epidermoid cancer of the lung","volume":"315","year":"1986","journal-title":"N Engl J Med"},{"key":"10.1016\/j.ijrobp.2012.03.018_bib53","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1016\/S0140-6736(98)22030-7","article-title":"Commentary: what now for postoperative radiotherapy for lung cancer?","volume":"352","author":"Munro","year":"1998","journal-title":"Lancet"},{"key":"10.1016\/j.ijrobp.2012.03.018_bib54","doi-asserted-by":"crossref","first-page":"3912","DOI":"10.1200\/JCO.2001.19.19.3912","article-title":"Risk of death from intercurrent disease is not excessively increased by modern postoperative radiotherapy for high-risk resected non-small-cell lung carcinoma","volume":"19","author":"Machtay","year":"2001","journal-title":"J Clin Oncol"},{"issue":"1","key":"10.1016\/j.ijrobp.2012.03.018_bib55","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1016\/j.radonc.2008.07.011","article-title":"Impact of the boost dose of 10Gy versus 26Gy in patients treated with early stage breast cancer after a microscopically incomplete lumpectomy: 10 year results of the randomized EORTC boost trial","volume":"90","author":"Poortsmans","year":"2009","journal-title":"Radiat Oncol"},{"key":"10.1016\/j.ijrobp.2012.03.018_bib56","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1016\/j.ijrobp.2010.05.022","article-title":"Failure rates and patterns of recurrence in patients with resected N1 non-small cell lung cancer","volume":"81","author":"Varlotto","year":"2011","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2012.03.018_bib57","series-title":"Perez and Brady's Principles and Practice of Radiation Oncology","first-page":"1076","article-title":"Lung","author":"Chang","year":"2008"},{"key":"10.1016\/j.ijrobp.2012.03.018_bib58","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/j.ijrobp.2009.10.030","article-title":"Mature follow-up for high-risk stage I non-small cell lung carcinoma treated with sub-lobar resection and intraoperative iodine-125 brachytherapy","volume":"79","author":"Colonias","year":"2011","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2012.03.018_bib59","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1016\/S0039-6060(03)00327-1","article-title":"Comparison between sublobar resection and 125Iodine brachytherapy after sublobar resection in high-risk patients with Stage I non-small-cell lung cancer","volume":"134","author":"Santos","year":"2003","journal-title":"Surgery"},{"key":"10.1016\/j.ijrobp.2012.03.018_bib60","doi-asserted-by":"crossref","first-page":"1143","DOI":"10.1016\/j.jtcvs.2011.07.051","article-title":"Thirty- and ninety-day outcomes after sublobar resection with and without brachytherapy for non-small cell lung cancer: results from a multicenter phase III study","volume":"142","author":"Fernando","year":"2011","journal-title":"J Thorac Cardiovasc Surg"},{"key":"10.1016\/j.ijrobp.2012.03.018_bib61","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1016\/j.ijrobp.2008.01.044","volume":"72","author":"Douillard","year":"2008","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2012.03.018_bib62","doi-asserted-by":"crossref","first-page":"1217","DOI":"10.1056\/NEJM200010263431703","article-title":"A randomized trial of postoperative adjuvant therapy in patients with completely resected stage II or IIIA non-small-cell lung cancer. Eastern Cooperative Oncology Group","volume":"343","author":"Keller","year":"2000","journal-title":"N Engl J Med"},{"key":"10.1016\/j.ijrobp.2012.03.018_bib63","doi-asserted-by":"crossref","first-page":"1356","DOI":"10.1056\/NEJM199605233342102","article-title":"The sequencing of chemotherapy and radiation therapy after conservative surgery for early-stage breast cancer","volume":"334","author":"Recht","year":"1996","journal-title":"N Engl J Med"},{"issue":"Suppl 2","key":"10.1016\/j.ijrobp.2012.03.018_bib64","doi-asserted-by":"crossref","first-page":"S19","DOI":"10.1016\/S0169-5002(08)70101-6","article-title":"The use of first-generation tyrosine kinase inhibitors in patients with NSCLC and somatic EGFR mutations","volume":"60","author":"Riely","year":"2008","journal-title":"Lung Cancer"},{"key":"10.1016\/j.ijrobp.2012.03.018_bib65","doi-asserted-by":"crossref","first-page":"983","DOI":"10.1056\/NEJMoa060570","article-title":"DNA repair by ERCC1 in non-small-cell lung cancer and cisplatin-based adjuvant chemotherapy","volume":"355","author":"Olaussen","year":"2006","journal-title":"N Engl J Med"},{"key":"10.1016\/j.ijrobp.2012.03.018_bib66","doi-asserted-by":"crossref","first-page":"4417","DOI":"10.1200\/JCO.2009.26.4325","article-title":"Prognostic and predictive gene signature for adjuvant chemotherapy in resected non-small-cell lung cancer","volume":"28","author":"Zhu","year":"2010","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.ijrobp.2012.03.018_bib67","doi-asserted-by":"crossref","first-page":"1693","DOI":"10.1056\/NEJMoa1006448","article-title":"Anaplastic lymphoma kinase inhibition in non-small-cell lung cancer","volume":"363","author":"Kwak","year":"2010","journal-title":"N Engl J Med"},{"key":"10.1016\/j.ijrobp.2012.03.018_bib68","doi-asserted-by":"crossref","first-page":"1014","DOI":"10.1016\/j.jtcvs.2005.12.057","article-title":"Histologic grade is an independent prognostic factor for survival in non-small cell lung cancer: an analysis of 5018 hospital- and 712 population-based cases","volume":"131","author":"Sun","year":"2006","journal-title":"J Thorac Cardiovasc Surg"},{"key":"10.1016\/j.ijrobp.2012.03.018_bib69","doi-asserted-by":"crossref","first-page":"5218","DOI":"10.1002\/cncr.24625","article-title":"Local recurrence after surgery for early stage lung cancer: an 11-year experience with 975 patients","volume":"115","author":"Kelsey","year":"2009","journal-title":"Cancer"},{"key":"10.1016\/j.ijrobp.2012.03.018_bib70","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1016\/j.lungcan.2011.07.019","article-title":"Confirmation of the role of diabetes in the local recurrence of surgically-resected non-small cell carcinoma of the lung","volume":"75","author":"Varlotto","year":"2012","journal-title":"Lung Cancer"},{"key":"10.1016\/j.ijrobp.2012.03.018_bib71","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1056\/NEJMoa1008862","article-title":"Diabetes mellitus, fasting glucose, and risk of cause-specific death","volume":"364","year":"2011","journal-title":"N Engl J Med"},{"key":"10.1016\/j.ijrobp.2012.03.018_bib72","doi-asserted-by":"crossref","first-page":"2390","DOI":"10.1002\/cncr.25047","article-title":"Varying recurrence rates and risk factors associated with different definitions of local recurrence in patients with surgically-resected stage I non-small cell lung cancer","volume":"116","author":"Varlotto","year":"2010","journal-title":"Cancer"}],"container-title":["International Journal of Radiation Oncology*Biology*Physics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0360301612004130?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0360301612004130?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T06:45:14Z","timestamp":1714545914000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0360301612004130"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,12]]},"references-count":72,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2012,12]]}},"alternative-id":["S0360301612004130"],"URL":"https:\/\/doi.org\/10.1016\/j.ijrobp.2012.03.018","relation":{},"ISSN":["0360-3016"],"issn-type":[{"value":"0360-3016","type":"print"}],"subject":[],"published":{"date-parts":[[2012,12]]}}}