{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,15]],"date-time":"2025-10-15T17:31:16Z","timestamp":1760549476074},"reference-count":25,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2014,3,1]],"date-time":"2014-03-01T00:00:00Z","timestamp":1393632000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["International Journal of Radiation Oncology*Biology*Physics"],"published-print":{"date-parts":[[2014,3]]},"DOI":"10.1016\/j.ijrobp.2013.11.009","type":"journal-article","created":{"date-parts":[[2014,1,8]],"date-time":"2014-01-08T14:00:16Z","timestamp":1389189616000},"page":"845-852","source":"Crossref","is-referenced-by-count":24,"title":["Residual Tumor After Neoadjuvant Chemoradiation Outside the Radiation Therapy Target Volume: A New Prognostic Factor for Survival in Esophageal Cancer"],"prefix":"10.1016","volume":"88","author":[{"given":"Christina","family":"Muijs","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Justin","family":"Smit","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arend","family":"Karrenbeld","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jannet","family":"Beukema","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Veronique","family":"Mul","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Go","family":"van Dam","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Geke","family":"Hospers","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Phillip","family":"Kluin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Johannes","family":"Langendijk","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John","family":"Plukker","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ijrobp.2013.11.009_bib1","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1002\/bjs.5983","article-title":"Effect of neoadjuvant chemotherapy on circumferential margin positivity and its impact on prognosis in patients with resectable oesophageal cancer","volume":"95","author":"Sujendran","year":"2008","journal-title":"Br J Surg"},{"key":"10.1016\/j.ijrobp.2013.11.009_bib2","doi-asserted-by":"crossref","first-page":"2074","DOI":"10.1056\/NEJMoa1112088","article-title":"Preoperative chemoradiotherapy for esophageal or junctional cancer","volume":"366","author":"van Hagen","year":"2012","journal-title":"N Engl J Med"},{"key":"10.1016\/j.ijrobp.2013.11.009_bib3","doi-asserted-by":"crossref","first-page":"1349","DOI":"10.1002\/cncr.21346","article-title":"Failure patterns correlate with the proportion of residual carcinoma after preoperative chemoradiotherapy for carcinoma of the esophagus","volume":"104","author":"Rohatgi","year":"2005","journal-title":"Cancer"},{"key":"10.1016\/j.ijrobp.2013.11.009_bib4","doi-asserted-by":"crossref","first-page":"2119","DOI":"10.1002\/cncr.21850","article-title":"The clinical impact of histopathologic response assessment by residual tumor cell quantification in esophageal squamous cell carcinomas","volume":"106","author":"Brucher","year":"2006","journal-title":"Cancer"},{"key":"10.1016\/j.ijrobp.2013.11.009_bib5","series-title":"AJCC Cancer Staging Manual","author":"Edge","year":"2009"},{"key":"10.1016\/j.ijrobp.2013.11.009_bib6","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1016\/j.ijrobp.2008.04.015","article-title":"Using (18)F-fluorodeoxyglucose positron emission tomography to estimate the length of gross tumor in patients with squamous cell carcinoma of the esophagus","volume":"73","author":"Zhong","year":"2009","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2013.11.009_bib7","series-title":"International Union Against Cancer (UICC) TNM Classification of Malignant Tumors","year":"2009"},{"key":"10.1016\/j.ijrobp.2013.11.009_bib8","series-title":"WHO Classification of Tumours, Pathology and Genetics, Tumours of the Digestive System","author":"Hamilton","year":"2000"},{"key":"10.1016\/j.ijrobp.2013.11.009_bib9","unstructured":"Royal College of Pathologists. Dataset for the histopathological reporting of oesophageal carcinoma. 2nd ed. 2007."},{"key":"10.1016\/j.ijrobp.2013.11.009_bib10","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1016\/j.ejso.2005.11.024","article-title":"The prognostic value of circumferential resection margin involvement in oesophageal malignancy","volume":"32","author":"Griffiths","year":"2006","journal-title":"Eur J Surg Oncol"},{"key":"10.1016\/j.ijrobp.2013.11.009_bib11","doi-asserted-by":"crossref","first-page":"2680","DOI":"10.1002\/1097-0142(19940601)73:11<2680::AID-CNCR2820731105>3.0.CO;2-C","article-title":"Pathologic assessment of tumor regression after preoperative chemoradiotherapy of esophageal carcinoma. Clinicopathologic correlations","volume":"73","author":"Mandard","year":"1994","journal-title":"Cancer"},{"key":"10.1016\/j.ijrobp.2013.11.009_bib12","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1111\/j.1442-2050.2009.01044.x","article-title":"Impact of 18-fluorodeoxyglucose positron emission tomography on computed tomography defined target volumes in radiation treatment planning of esophageal cancer: reduction in geographic misses with equal inter-observer variability","volume":"23","author":"Schreurs","year":"2010","journal-title":"Dis Esophagus"},{"key":"10.1016\/j.ijrobp.2013.11.009_bib13","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1016\/S0360-3016(98)00216-8","article-title":"Variability of target volume delineation in cervical esophageal cancer","volume":"42","author":"Tai","year":"1998","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2013.11.009_bib14","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1007\/s12149-007-0040-0","article-title":"Pre-operative estimation of esophageal tumor metabolic length in FDG-PET images with surgical pathology confirmation 14","volume":"21","author":"Mamede","year":"2007","journal-title":"Ann Nucl Med"},{"key":"10.1016\/j.ijrobp.2013.11.009_bib15","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/j.radonc.2010.04.024","article-title":"A systematic review on the role of FDG-PET\/CT in tumour delineation and radiotherapy planning in patients with esophageal cancer","volume":"97","author":"Muijs","year":"2010","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.ijrobp.2013.11.009_bib16","doi-asserted-by":"crossref","first-page":"1776","DOI":"10.1002\/cncr.20585","article-title":"2-Fluoro-2-deoxy-D-glucose positron emission tomography imaging is predictive of pathologic response and survival after preoperative chemoradiation in patients with esophageal carcinoma","volume":"101","author":"Swisher","year":"2004","journal-title":"Cancer"},{"key":"10.1016\/j.ijrobp.2013.11.009_bib17","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1016\/S0748-7983(03)00109-4","article-title":"Extent of oesophageal resection for adenocarcinoma of the oesophagogastric junction","volume":"29","author":"Mariette","year":"2003","journal-title":"Eur J Surg Oncol"},{"key":"10.1016\/j.ijrobp.2013.11.009_bib18","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1097\/01.sla.0000255563.65157.d2","article-title":"Adenocarcinoma of the gastroesophageal junction: influence of esophageal resection margin and operative approach on outcome","volume":"246","author":"Barbour","year":"2007","journal-title":"Ann Surg"},{"key":"10.1016\/j.ijrobp.2013.11.009_bib19","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1016\/j.ijrobp.2006.09.015","article-title":"Pathological analysis of clinical target volume margin for radiotherapy in patients with esophageal and gastroesophageal junction carcinoma","volume":"67","author":"Gao","year":"2007","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2013.11.009_bib20","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1016\/j.radonc.2009.03.018","article-title":"EORTC-ROG expert opinion: radiotherapy volume and treatment guidelines for neoadjuvant radiation of adenocarcinomas of the gastroesophageal junction and the stomach","volume":"92","author":"Matzinger","year":"2009","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.ijrobp.2013.11.009_bib21","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1002\/cncr.22397","article-title":"Detection of interval distant metastases: clinical utility of integrated CT-PET imaging in patients with esophageal carcinoma after neoadjuvant therapy","volume":"109","author":"Bruzzi","year":"2007","journal-title":"Cancer"},{"key":"10.1016\/j.ijrobp.2013.11.009_bib22","doi-asserted-by":"crossref","first-page":"1232","DOI":"10.1016\/j.jtcvs.2004.12.042","article-title":"The accuracy of endoscopic ultrasonography with fine-needle aspiration, integrated positron emission tomography with computed tomography, and computed tomography in restaging patients with esophageal cancer after neoadjuvant chemoradiotherapy","volume":"129","author":"Cerfolio","year":"2005","journal-title":"J Thorac Cardiovasc Surg"},{"key":"10.1016\/j.ijrobp.2013.11.009_bib23","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1093\/annonc\/mdf081","article-title":"Positron emission tomography for assessment of the response to induction radiochemotherapy in locally advanced oesophageal cancer","volume":"13","author":"Flamen","year":"2002","journal-title":"Ann Oncol"},{"key":"10.1016\/j.ijrobp.2013.11.009_bib24","doi-asserted-by":"crossref","first-page":"774","DOI":"10.1016\/j.ejso.2011.06.002","article-title":"The value of post-neoadjuvant therapy PET-CT in the detection of interval metastases in esophageal carcinoma","volume":"37","author":"Blom","year":"2011","journal-title":"Eur J Surg Oncol"},{"key":"10.1016\/j.ijrobp.2013.11.009_bib25","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1016\/j.radonc.2012.10.015","article-title":"Oesophageal tumour progression between the diagnostic (18)F-FDG-PET and the (18)F-FDG-PET for radiotherapy treatment planning","volume":"106","author":"Muijs","year":"2013","journal-title":"Radiother Oncol"}],"container-title":["International Journal of Radiation Oncology*Biology*Physics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0360301613033129?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0360301613033129?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,10,7]],"date-time":"2018-10-07T15:21:36Z","timestamp":1538925696000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0360301613033129"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,3]]},"references-count":25,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2014,3]]}},"alternative-id":["S0360301613033129"],"URL":"https:\/\/doi.org\/10.1016\/j.ijrobp.2013.11.009","relation":{},"ISSN":["0360-3016"],"issn-type":[{"value":"0360-3016","type":"print"}],"subject":[],"published":{"date-parts":[[2014,3]]}}}