{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T06:11:59Z","timestamp":1790230319793,"version":"4.1.0"},"reference-count":18,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2014,5,1]],"date-time":"2014-05-01T00:00:00Z","timestamp":1398902400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["International Journal of Radiation Oncology*Biology*Physics"],"published-print":{"date-parts":[[2014,5]]},"DOI":"10.1016\/j.ijrobp.2014.01.032","type":"journal-article","created":{"date-parts":[[2014,4,9]],"date-time":"2014-04-09T21:33:41Z","timestamp":1397079221000},"page":"88-95","source":"Crossref","is-referenced-by-count":123,"title":["Manifestation Pattern of Early-Late Vaginal Morbidity After Definitive Radiation (Chemo)Therapy and Image-Guided Adaptive Brachytherapy for Locally Advanced Cervical Cancer: An Analysis From the EMBRACE Study"],"prefix":"10.1016","volume":"89","author":[{"given":"Kathrin","family":"Kirchheiner","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Remi A.","family":"Nout","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kari","family":"Tanderup","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacob C.","family":"Lindegaard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henrike","family":"Westerveld","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christine","family":"Haie-Meder","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Primo\u017e","family":"Petri\u010d","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Umesh","family":"Mahantshetty","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wolfgang","family":"D\u00f6rr","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard","family":"P\u00f6tter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ijrobp.2014.01.032_bib1","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1053\/j.seminoncol.2008.12.007","article-title":"Management of early and locally advanced cervical cancer","volume":"36","author":"Barbera","year":"2009","journal-title":"Semin Oncol"},{"key":"10.1016\/j.ijrobp.2014.01.032_bib2","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/j.radonc.2004.12.015","article-title":"Recommendations from Gynaecological (GYN) GEC-ESTRO Working Group (I): Concepts and terms in 3D image based 3D treatment planning in cervix cancer brachytherapy with emphasis on MRI assessment of GTV and CTV","volume":"74","author":"Haie-Meder","year":"2005","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.ijrobp.2014.01.032_bib3","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.radonc.2005.11.014","article-title":"Recommendations from Gynaecological (GYN) GEC ESTRO working group (II): Concepts and terms in 3D image-based treatment planning in cervix cancer brachytherapy-3D dose volume parameters and aspects of 3D image-based anatomy, radiation physics, radiobiology","volume":"78","author":"P\u00f6tter","year":"2006","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.ijrobp.2014.01.032_bib4","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1016\/j.radonc.2007.04.012","article-title":"Clinical impact of MRI assisted dose volume adaptation and dose escalation in brachytherapy of locally advanced cervix cancer","volume":"83","author":"P\u00f6tter","year":"2007","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.ijrobp.2014.01.032_bib5","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1016\/j.radonc.2011.07.012","article-title":"Clinical outcome of protocol based image (MRI) guided adaptive brachytherapy combined with 3D conformal radiotherapy with or without chemotherapy in patients with locally advanced cervical cancer","volume":"100","author":"P\u00f6tter","year":"2011","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.ijrobp.2014.01.032_bib6","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1016\/j.radonc.2012.04.007","article-title":"Impact of 3D image-based PDR brachytherapy on outcome of patients treated for cervix carcinoma in France: Results of the French STIC prospective study","volume":"103","author":"Charra-Brunaud","year":"2012","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.ijrobp.2014.01.032_bib7","doi-asserted-by":"crossref","first-page":"1510","DOI":"10.3109\/0284186X.2013.818253","article-title":"MRI-guided adaptive radiotherapy in locally advanced cervical cancer from a Nordic perspective","volume":"52","author":"Lindegaard","year":"2013","journal-title":"Acta Oncol"},{"key":"10.1016\/j.ijrobp.2014.01.032_bib8","doi-asserted-by":"crossref","first-page":"5802","DOI":"10.1200\/JCO.2008.16.4368","article-title":"Reducing uncertainties about the effects of chemoradiotherapy for cervical cancer: A systematic review and meta-analysis of individual patient data from 18 randomized trials","volume":"26","author":"Vale","year":"2008","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.ijrobp.2014.01.032_bib9","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/j.radonc.2010.01.001","article-title":"From point A to the sculpted pear: MR image guidance significantly improves tumour dose and sparing of organs at risk in brachytherapy of cervical cancer","volume":"94","author":"Tanderup","year":"2010","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.ijrobp.2014.01.032_bib10","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/j.radonc.2013.04.009","article-title":"Vaginal dose point reporting in cervical cancer patients treated with combined 2D\/3D external beam radiotherapy and 2D\/3D brachytherapy","volume":"107","author":"Westerveld","year":"2013","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.ijrobp.2014.01.032_bib11","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1016\/j.radonc.2010.05.005","article-title":"Dose volume parameter D2cc does not correlate with vaginal side effects in individual patients with cervical cancer treated within a defined treatment protocol with very high brachytherapy doses","volume":"97","author":"Fidarova","year":"2010","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.ijrobp.2014.01.032_bib12","doi-asserted-by":"crossref","first-page":"1383","DOI":"10.1056\/NEJM199905063401802","article-title":"Vaginal changes and sexuality in women with a history of cervical cancer","volume":"340","author":"Bergmark","year":"1999","journal-title":"N Engl J Med"},{"key":"10.1016\/j.ijrobp.2014.01.032_bib13","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1002\/pon.639","article-title":"Post-treatment sexual adjustment following cervical and endometrial cancer: A qualitative insight","volume":"12","author":"Juraskova","year":"2003","journal-title":"Psychooncology"},{"key":"10.1016\/j.ijrobp.2014.01.032_bib14","unstructured":"Cancer Therapy Evaluation Program, Common Terminology Criteria for Adverse Events, Version 3.0, DCTD, NCI, NIH, DHHS March 31, 2003 (http:\/\/ctep.cancer.gov). Publish date: August 9,\u00a02006."},{"key":"10.1016\/j.ijrobp.2014.01.032_bib15","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1016\/S1053-4296(03)00031-6","article-title":"CTCAE v3.0: Development of a comprehensive grading system for the adverse effects of cancer treatment","volume":"13","author":"Trotti","year":"2003","journal-title":"Semin Radiat Oncol"},{"key":"10.1016\/j.ijrobp.2014.01.032_bib16","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/S1278-3218(00)88900-3","article-title":"Definitive radiotherapy based on HDR brachytherapy with iridium 192 in uterine cervix carcinoma: Report on the Vienna University Hospital findings (1993-1997) compared to the preceding period in the context of ICRU 38 recommendations","volume":"4","author":"P\u00f6tter","year":"2000","journal-title":"Cancer Radiother"},{"key":"10.1016\/j.ijrobp.2014.01.032_bib17","doi-asserted-by":"crossref","first-page":"933","DOI":"10.1007\/s00066-012-0156-6","article-title":"Do clinicians and patients agree regarding symptoms? A comparison after definitive radiochemotherapy in 223 uterine cervical cancer patients","volume":"188","author":"Kirchheiner","year":"2012","journal-title":"Strahlenther Onkol"},{"key":"10.1016\/j.ijrobp.2014.01.032_bib18","doi-asserted-by":"crossref","first-page":"1531","DOI":"10.1016\/0360-3016(95)00262-W","article-title":"Why actuarial estimates should be used in reporting late normal-tissue effects of cancer treatment\u2026 now!","volume":"32","author":"Bentzen","year":"1995","journal-title":"Int J Radiat Oncol Biol Phys"}],"container-title":["International Journal of Radiation Oncology*Biology*Physics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0360301614001072?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0360301614001072?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,10,4]],"date-time":"2018-10-04T22:58:47Z","timestamp":1538693927000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0360301614001072"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,5]]},"references-count":18,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2014,5]]}},"alternative-id":["S0360301614001072"],"URL":"https:\/\/doi.org\/10.1016\/j.ijrobp.2014.01.032","relation":{},"ISSN":["0360-3016"],"issn-type":[{"value":"0360-3016","type":"print"}],"subject":[],"published":{"date-parts":[[2014,5]]}}}