{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,5]],"date-time":"2025-11-05T20:53:15Z","timestamp":1762375995001,"version":"3.40.5"},"reference-count":34,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2015,11,1]],"date-time":"2015-11-01T00:00:00Z","timestamp":1446336000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["redjournal.org","clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Journal of Radiation Oncology*Biology*Physics"],"published-print":{"date-parts":[[2015,11]]},"DOI":"10.1016\/j.ijrobp.2015.08.007","type":"journal-article","created":{"date-parts":[[2015,8,8]],"date-time":"2015-08-08T06:37:40Z","timestamp":1439015860000},"page":"788-796","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":34,"title":["Assessment of Parametrial Response by Growth Pattern in Patients With International Federation of Gynecology and Obstetrics Stage IIB and IIIB Cervical Cancer: Analysis of Patients From a Prospective, Multicenter Trial (EMBRACE)"],"prefix":"10.1016","volume":"93","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5103-8549","authenticated-orcid":false,"given":"Kenji","family":"Yoshida","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Noha","family":"Jastaniyah","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alina","family":"Sturdza","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jacob","family":"Lindegaard","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Barbara","family":"Segedin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Umesh","family":"Mahantshetty","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bhavana","family":"Rai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ina","family":"J\u00fcrgenliemk-Schulz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8917-0297","authenticated-orcid":false,"given":"Christine","family":"Haie-Meder","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ryohei","family":"Sasaki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard","family":"P\u00f6tter","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ijrobp.2015.08.007_bib1","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1016\/S0360-3016(98)00067-4","article-title":"Tumor size, irradiation dose, and long-term outcome of carcinoma of uterine cervix","volume":"41","author":"Perez","year":"1998","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2015.08.007_bib2","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1016\/S0360-3016(97)00766-9","article-title":"Impact of the extent of parametrial involvement in patients with carcinoma of the uterine cervix","volume":"40","author":"Hsu","year":"1998","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2015.08.007_bib3","doi-asserted-by":"crossref","first-page":"1323","DOI":"10.1016\/j.ijrobp.2008.12.081","article-title":"Tumor heterogeneity of FIGO stage III carcinoma of the uterine cervix","volume":"75","author":"Kim","year":"2009","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2015.08.007_bib4","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.ijrobp.2006.04.041","article-title":"The Vienna applicator for combined intracavitary and interstitial brachytherapy of cervical cancer: Clinical feasibility and preliminary results","volume":"66","author":"Dimopoulos","year":"2006","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2015.08.007_bib5","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1016\/j.ijrobp.2007.06.033","article-title":"Cervical cancer regression measured using weekly magnetic resonance imaging during fractionated radiotherapy: Radiobiologic modeling and correlation with tumor hypoxia","volume":"70","author":"Lim","year":"2008","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2015.08.007_bib6","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/j.ijrobp.2008.03.064","article-title":"Cervix regression and motion during the course of external beam chemoradiation for cervical cancer","volume":"73","author":"Beadle","year":"2009","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2015.08.007_bib7","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1007\/s00066-012-0260-7","article-title":"Residual tumour volumes and grey zones after external beam radiotherapy (with or without chemotherapy) in cervical cancer patients. A low-field MRI study","volume":"189","author":"Schmid","year":"2013","journal-title":"Strahlenther Onkol"},{"key":"10.1016\/j.ijrobp.2015.08.007_bib8","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/j.radonc.2011.12.024","article-title":"Recommendations from Gynaecological (GYN) GEC-ESTRO Working Group (IV): Basic principles and parameters for MR imaging within the frame of image based adaptive cervix cancer brachytherapy","volume":"103","author":"Dimopoulos","year":"2012","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.ijrobp.2015.08.007_bib9","doi-asserted-by":"crossref","first-page":"1384","DOI":"10.3109\/0284186X.2013.818251","article-title":"Magnetic resonance imaging for assessment of parametrial tumour spread and regression patterns in adaptive cervix cancer radiotherapy","volume":"52","author":"Schmid","year":"2013","journal-title":"Acta Oncol"},{"key":"10.1016\/j.ijrobp.2015.08.007_bib10","doi-asserted-by":"crossref","first-page":"915","DOI":"10.1016\/0360-3016(96)00230-1","article-title":"Usefulness of tumor volumetry by magnetic resonance imaging in assessing response to radiation therapy in carcinoma of the uterine cervix","volume":"35","author":"Mayr","year":"1996","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2015.08.007_bib11","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1016\/S0360-3016(99)00228-X","article-title":"Evaluation of the therapeutic effect of radiotherapy on cervical cancer using magnetic resonance imaging","volume":"45","author":"Hatano","year":"1999","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2015.08.007_bib12","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/S0360-3016(01)01808-9","article-title":"Method and timing of tumor volume measurement for outcome prediction in cervical cancer using magnetic resonance imaging","volume":"52","author":"Mayr","year":"2002","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2015.08.007_bib13","doi-asserted-by":"crossref","first-page":"5093","DOI":"10.1002\/cncr.25260","article-title":"Sequential magnetic resonance imaging of cervical cancer: The predictive value of absolute tumor volume and regression ratio measured before, during, and after radiation therapy","volume":"116","author":"Wang","year":"2010","journal-title":"Cancer"},{"key":"10.1016\/j.ijrobp.2015.08.007_bib14","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1016\/j.ijrobp.2009.02.036","article-title":"Translating response during therapy into ultimate treatment outcome: A personalized 4-dimensional MRI tumor volumetric regression approach in cervical cancer","volume":"76","author":"Mayr","year":"2010","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2015.08.007_bib15","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1016\/j.radonc.2009.07.001","article-title":"Dose-effect relationship for local control of cervical cancer by magnetic resonance image-guided brachytherapy","volume":"93","author":"Dimopoulos","year":"2009","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.ijrobp.2015.08.007_bib16","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1016\/j.ygyno.2014.02.004","article-title":"Distant metastasis in patients with cervical cancer after primary radiotherapy with or without chemotherapy and image guided adaptive brachytherapy","volume":"133","author":"Schmid","year":"2014","journal-title":"Gynecol Oncol"},{"key":"10.1016\/j.ijrobp.2015.08.007_bib17","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/j.radonc.2004.12.015","article-title":"Recommendations from Gynaecological (GYN) GEC-ESTRO Working Group (I): Concepts and terms in 3D image based 3D treatment planning in cervix cancer brachytherapy with emphasis on MRI assessment of GTV and CTV","volume":"74","author":"Haie-Meder","year":"2005","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.ijrobp.2015.08.007_bib18","doi-asserted-by":"crossref","first-page":"65","DOI":"10.2214\/AJR.05.0039","article-title":"Serial therapy-induced changes in tumor shape in cervical cancer and their impact on assessing tumor volume and treatment response","volume":"187","author":"Mayr","year":"2006","journal-title":"AJR Am J Roentgenol"},{"key":"10.1016\/j.ijrobp.2015.08.007_bib19","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/j.ygyno.2004.06.025","article-title":"Prognostic difference of surgical treatment of exophytic versus barrel-shaped bulky cervical cancer","volume":"95","author":"Trimbos","year":"2004","journal-title":"Gynecol Oncol"},{"key":"10.1016\/j.ijrobp.2015.08.007_bib20","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1016\/j.ygyno.2010.02.014","article-title":"Local spread of cervical cancer revisited: A clinical and pathological pattern analysis","volume":"117","author":"Hockel","year":"2010","journal-title":"Gynecol Oncol"},{"key":"10.1016\/j.ijrobp.2015.08.007_bib21","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1148\/radiol.2282011860","article-title":"Measurement of observer agreement","volume":"228","author":"Kundel","year":"2003","journal-title":"Radiology"},{"key":"10.1016\/j.ijrobp.2015.08.007_bib22","first-page":"1464","article-title":"Defining the learning curve for multiparametric magnetic resonance imaging (MRI) of the prostate using MRI-transrectal ultrasonography (TRUS) fusion-guided transperineal prostate biopsies as a validation tool","author":"Gaziev","year":"2015","journal-title":"BJU Int"},{"key":"10.1016\/j.ijrobp.2015.08.007_bib23","doi-asserted-by":"crossref","first-page":"4006","DOI":"10.1038\/ncomms5006","article-title":"Decoding tumour phenotype by noninvasive imaging using a quantitative radiomics approach","volume":"5","author":"Aerts","year":"2014","journal-title":"Nat Commun"},{"key":"10.1016\/j.ijrobp.2015.08.007_bib24","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1016\/j.radonc.2013.01.014","article-title":"Uncertainties of target volume delineation in MRI guided adaptive brachytherapy of cervix cancer: A multi-institutional study","volume":"107","author":"Petric","year":"2013","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.ijrobp.2015.08.007_bib25","doi-asserted-by":"crossref","first-page":"9329","DOI":"10.1200\/JCO.2005.02.0354","article-title":"Role of imaging in pretreatment evaluation of early invasive cervical cancer: Results of the intergroup study American College of Radiology Imaging Network 6651-Gynecologic Oncology Group 183","volume":"23","author":"Hricak","year":"2005","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.ijrobp.2015.08.007_bib26","doi-asserted-by":"crossref","first-page":"e307","DOI":"10.1016\/j.jviscsurg.2012.10.010","article-title":"Extra-vascular dissection of the pelvic sidewall for advanced cancers of the pelvis. A technique to obtain wider lateral resection margins","volume":"149","author":"Pereira","year":"2012","journal-title":"J Visc Surg"},{"key":"10.1016\/j.ijrobp.2015.08.007_bib27","doi-asserted-by":"crossref","first-page":"1155","DOI":"10.1148\/radiographics.21.5.g01se311155","article-title":"CT evaluation of cervical cancer: Spectrum of disease","volume":"21","author":"Pannu","year":"2001","journal-title":"Radiographics"},{"key":"10.1016\/j.ijrobp.2015.08.007_bib28","doi-asserted-by":"crossref","first-page":"1577","DOI":"10.2214\/AJR.06.1196","article-title":"MRI of malignant neoplasms of the uterine corpus and cervix","volume":"188","author":"Sala","year":"2007","journal-title":"AJR Am J Roentgenol"},{"key":"10.1016\/j.ijrobp.2015.08.007_bib29","doi-asserted-by":"crossref","first-page":"247","DOI":"10.4103\/0971-3026.120257","article-title":"MR imaging of carcinoma cervix","volume":"23","author":"Mahajan","year":"2013","journal-title":"Indian J Radiol Imaging"},{"key":"10.1016\/j.ijrobp.2015.08.007_bib30","doi-asserted-by":"crossref","first-page":"941","DOI":"10.3109\/0284186X.2010.510145","article-title":"Evaluating repetitive 18F-fluoroazomycin-arabinoside (18FAZA) PET in the setting of MRI guided adaptive radiotherapy in cervical cancer","volume":"49","author":"Schuetz","year":"2010","journal-title":"Acta Oncol"},{"key":"10.1016\/j.ijrobp.2015.08.007_bib31","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1093\/jnci\/93.4.266","article-title":"Tumor hypoxia: Definitions and current clinical, biologic, and molecular aspects","volume":"93","author":"Hockel","year":"2001","journal-title":"J Natl Cancer Inst"},{"key":"10.1016\/j.ijrobp.2015.08.007_bib32","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/0167-8140(93)90025-4","article-title":"Intratumoral pO2 predicts survival in advanced cancer of the uterine cervix","volume":"26","author":"Hockel","year":"1993","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.ijrobp.2015.08.007_bib33","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/S0167-8140(99)00139-5","article-title":"Intratumoral pO2-measurements as predictive assay in the treatment of carcinoma of the uterine cervix","volume":"53","author":"Knocke","year":"1999","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.ijrobp.2015.08.007_bib34","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/j.semradonc.2011.12.009","article-title":"Biological predictors of cervical cancer response to radiation therapy","volume":"22","author":"Klopp","year":"2012","journal-title":"Semin Radiat Oncol"}],"container-title":["International Journal of Radiation Oncology*Biology*Physics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S036030161503120X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S036030161503120X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,8,29]],"date-time":"2019-08-29T01:16:47Z","timestamp":1567041407000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S036030161503120X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,11]]},"references-count":34,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2015,11]]}},"alternative-id":["S036030161503120X"],"URL":"https:\/\/doi.org\/10.1016\/j.ijrobp.2015.08.007","relation":{},"ISSN":["0360-3016"],"issn-type":[{"type":"print","value":"0360-3016"}],"subject":[],"published":{"date-parts":[[2015,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Assessment of Parametrial Response by Growth Pattern in Patients With International Federation of Gynecology and Obstetrics Stage IIB and IIIB Cervical Cancer: Analysis of Patients From a Prospective, Multicenter Trial (EMBRACE)","name":"articletitle","label":"Article Title"},{"value":"International Journal of Radiation Oncology*Biology*Physics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ijrobp.2015.08.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}