{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T22:05:14Z","timestamp":1792101914724,"version":"4.4.0"},"reference-count":22,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2016,8,1]],"date-time":"2016-08-01T00:00:00Z","timestamp":1470009600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["redjournal.org","clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Journal of Radiation Oncology*Biology*Physics"],"published-print":{"date-parts":[[2016,8]]},"DOI":"10.1016\/j.ijrobp.2016.03.050","type":"journal-article","created":{"date-parts":[[2016,4,9]],"date-time":"2016-04-09T23:13:35Z","timestamp":1460243615000},"page":"1399-1404","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":140,"title":["Radiosensitivity Differences Between Liver Metastases Based on Primary Histology Suggest Implications for Clinical Outcomes After Stereotactic Body Radiation Therapy"],"prefix":"10.1016","volume":"95","author":[{"given":"Kamran A.","family":"Ahmed","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jimmy J.","family":"Caudell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ghassan","family":"El-Haddad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anders E.","family":"Berglund","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric A.","family":"Welsh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Binglin","family":"Yue","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah E.","family":"Hoffe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arash O.","family":"Naghavi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yazan A.","family":"Abuodeh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jessica M.","family":"Frakes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven A.","family":"Eschrich","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Javier F.","family":"Torres-Roca","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ijrobp.2016.03.050_bib1","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1200\/JCO.2001.19.1.164","article-title":"Stereotactic single-dose radiation therapy of liver tumors: Results of a phase I\/II trial","volume":"19","author":"Herfarth","year":"2001","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.ijrobp.2016.03.050_bib2","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1080\/02841860600904854","article-title":"Phase II study on stereotactic body radiotherapy of colorectal metastases","volume":"45","author":"Hoyer","year":"2006","journal-title":"Acta Oncol"},{"key":"10.1016\/j.ijrobp.2016.03.050_bib3","doi-asserted-by":"crossref","first-page":"1585","DOI":"10.1200\/JCO.2008.20.0600","article-title":"Phase I study of individualized stereotactic body radiotherapy of liver metastases","volume":"27","author":"Lee","year":"2009","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.ijrobp.2016.03.050_bib4","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1016\/j.ijrobp.2012.12.021","article-title":"Is stereotactic body radiation therapy an attractive option for unresectable liver metastases? A preliminary report from a phase 2 trial","volume":"86","author":"Scorsetti","year":"2013","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2016.03.050_bib5","doi-asserted-by":"crossref","first-page":"1572","DOI":"10.1200\/JCO.2008.19.6329","article-title":"Multi-institutional phase I\/II trial of stereotactic body radiation therapy for liver metastases","volume":"27","author":"Rusthoven","year":"2009","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.ijrobp.2016.03.050_bib6","doi-asserted-by":"crossref","first-page":"838","DOI":"10.1080\/02841860600904821","article-title":"Stereotactic radiotherapy of primary liver cancer and hepatic metastases","volume":"45","author":"Wulf","year":"2006","journal-title":"Acta Oncol"},{"key":"10.1016\/j.ijrobp.2016.03.050_bib7","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1016\/j.ijrobp.2008.03.062","article-title":"Observation of a dose-control relationship for lung and liver tumors after stereotactic body radiation therapy","volume":"73","author":"McCammon","year":"2009","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2016.03.050_bib8","doi-asserted-by":"crossref","first-page":"878","DOI":"10.1016\/j.ijrobp.2011.08.036","article-title":"Oligometastases treated with stereotactic body radiotherapy: Long-term follow-up of prospective study","volume":"83","author":"Milano","year":"2012","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2016.03.050_bib9","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1016\/j.ijrobp.2009.06.014","article-title":"A gene expression model of intrinsic tumor radiosensitivity: Prediction of response and prognosis after chemoradiation","volume":"75","author":"Eschrich","year":"2009","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2016.03.050_bib10","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1016\/j.ijrobp.2015.01.036","article-title":"Differences between colon cancer primaries and metastases using a molecular assay for tumor radiation sensitivity suggest implications for potential oligometastatic SBRT patient selection","volume":"92","author":"Ahmed","year":"2015","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2016.03.050_bib11","doi-asserted-by":"crossref","first-page":"34414","DOI":"10.18632\/oncotarget.5437","article-title":"The radiosensitivity index predicts for overall survival in glioblastoma","volume":"6","author":"Ahmed","year":"2015","journal-title":"Oncotarget"},{"key":"10.1016\/j.ijrobp.2016.03.050_bib12","doi-asserted-by":"crossref","first-page":"5134","DOI":"10.1158\/1078-0432.CCR-12-0891","article-title":"Validation of a radiosensitivity molecular signature in breast cancer","volume":"18","author":"Eschrich","year":"2012","journal-title":"Clin Cancer Res"},{"key":"10.1016\/j.ijrobp.2016.03.050_bib13","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/j.radonc.2015.07.018","article-title":"Radiosensitivity index predicts for survival with adjuvant radiation in resectable pancreatic cancer","volume":"117","author":"Strom","year":"2015","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.ijrobp.2016.03.050_bib14","doi-asserted-by":"crossref","first-page":"S157","DOI":"10.1016\/j.ijrobp.2014.05.642","article-title":"A molecular signature of radiosensitivity (RSI) is an RT-specific biomarker in prostate cancer","volume":"90","author":"Torres-Roca","year":"2014","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2016.03.050_bib15","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1097\/PPO.0b013e318238216e","article-title":"Implementing personalized medicine in a cancer center","volume":"17","author":"Fenstermacher","year":"2011","journal-title":"Cancer J"},{"key":"10.1016\/j.ijrobp.2016.03.050_bib16","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1186\/1471-2105-14-153","article-title":"Iterative rank-order normalization of gene expression microarray data","volume":"14","author":"Welsh","year":"2013","journal-title":"BMC Bioinformatics"},{"key":"10.1016\/j.ijrobp.2016.03.050_bib17","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1137\/0905052","article-title":"The collinearity problem in linear regression. The partial least squares (PLS) approach to generalized inverses","volume":"5","author":"Wold","year":"1984","journal-title":"SIAM J Sci Stat Comput"},{"key":"10.1016\/j.ijrobp.2016.03.050_bib18","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1016\/j.ijrobp.2009.05.056","article-title":"Systems biology modeling of the radiation sensitivity network: A biomarker discovery platform","volume":"75","author":"Eschrich","year":"2009","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2016.03.050_bib19","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1016\/j.ejca.2008.10.026","article-title":"New response evaluation criteria in solid tumours: Revised RECIST guideline (version 1.1)","volume":"45","author":"Eisenhauer","year":"2009","journal-title":"Eur J Cancer"},{"key":"10.1016\/j.ijrobp.2016.03.050_bib20","doi-asserted-by":"crossref","first-page":"1047","DOI":"10.1016\/j.ijrobp.2011.07.020","article-title":"Radiotherapy for liver metastases: A review of evidence","volume":"82","author":"Hoyer","year":"2012","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2016.03.050_bib21","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1016\/j.radonc.2011.05.033","article-title":"Stereotactic body radiotherapy (SBRT) for oligometastatic lung tumors from colorectal cancer and other primary cancers in comparison with primary lung cancer","volume":"101","author":"Takeda","year":"2011","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.ijrobp.2016.03.050_bib22","doi-asserted-by":"crossref","first-page":"650","DOI":"10.1002\/cncr.23209","article-title":"A prospective pilot study of curative-intent stereotactic body radiation therapy in patients with 5 or fewer oligometastatic lesions","volume":"112","author":"Milano","year":"2008","journal-title":"Cancer"}],"container-title":["International Journal of Radiation Oncology*Biology*Physics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0360301616300402?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0360301616300402?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,9,6]],"date-time":"2019-09-06T07:48:31Z","timestamp":1567756111000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0360301616300402"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,8]]},"references-count":22,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2016,8]]}},"alternative-id":["S0360301616300402"],"URL":"https:\/\/doi.org\/10.1016\/j.ijrobp.2016.03.050","relation":{},"ISSN":["0360-3016"],"issn-type":[{"value":"0360-3016","type":"print"}],"subject":[],"published":{"date-parts":[[2016,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Radiosensitivity Differences Between Liver Metastases Based on Primary Histology Suggest Implications for Clinical Outcomes After Stereotactic Body Radiation Therapy","name":"articletitle","label":"Article Title"},{"value":"International Journal of Radiation Oncology*Biology*Physics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ijrobp.2016.03.050","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}