{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T06:12:20Z","timestamp":1790230340186,"version":"4.1.0"},"reference-count":35,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2019,3,1]],"date-time":"2019-03-01T00:00:00Z","timestamp":1551398400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,3,1]],"date-time":"2019-03-01T00:00:00Z","timestamp":1551398400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100002669","name":"Elekta","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002669","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007210","name":"Varian","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007210","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008363","name":"Danish Cancer Society","doi-asserted-by":"publisher","award":["R125-A7753-15-S37"],"award-info":[{"award-number":["R125-A7753-15-S37"]}],"id":[{"id":"10.13039\/100008363","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005940","name":"Danish Cancer Research Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005940","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","redjournal.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Journal of Radiation Oncology*Biology*Physics"],"published-print":{"date-parts":[[2019,3]]},"DOI":"10.1016\/j.ijrobp.2018.11.006","type":"journal-article","created":{"date-parts":[[2018,11,9]],"date-time":"2018-11-09T22:32:03Z","timestamp":1541802723000},"page":"887-894","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":52,"title":["Risk Factors for Ureteral Stricture After Radiochemotherapy Including Image Guided Adaptive Brachytherapy in Cervical Cancer: Results From the EMBRACE Studies"],"prefix":"10.1016","volume":"103","author":[{"given":"Lars","family":"Fokdal","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kari","family":"Tanderup","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard","family":"P\u00f6tter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alina","family":"Sturdza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathrin","family":"Kirchheiner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cyrus","family":"Chargari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ina Maria","family":"J\u00fcrgenliemk-Schulz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barbara","family":"Segedin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li-Tee","family":"Tan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Hoskin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Umesh","family":"Mahantshetty","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kjersti","family":"Bruheim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bhavana","family":"Rai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Kirisits","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacob Christian","family":"Lindegaard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ijrobp.2018.11.006_bib1","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/j.ijrobp.2008.06.1912","article-title":"Physics contributions and clinical outcome with 3D-MRI-based pulsed-dose-rate intracavitary brachytherapy in cervical cancer patients","volume":"74","author":"Chargari","year":"2009","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2018.11.006_bib2","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1016\/j.radonc.2012.04.007","article-title":"Impact of 3D image-based PDR brachytherapy on outcome of patients treated for cervix carcinoma in France: Results of the French STIC prospective study","volume":"103","author":"Charra-Brunaud","year":"2012","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.ijrobp.2018.11.006_bib3","doi-asserted-by":"crossref","first-page":"1510","DOI":"10.3109\/0284186X.2013.818253","article-title":"MRI-guided adaptive radiotherapy in locally advanced cervical cancer from a Nordic perspective","volume":"52","author":"Lindegaard","year":"2013","journal-title":"Acta Oncol"},{"key":"10.1016\/j.ijrobp.2018.11.006_bib4","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1634\/theoncologist.2012-0367","article-title":"Adaptive 3D image-guided brachytherapy: A strong argument in the debate on systematic radical hysterectomy for locally advanced cervical cancer","volume":"18","author":"Mazeron","year":"2013","journal-title":"Oncologist"},{"key":"10.1016\/j.ijrobp.2018.11.006_bib5","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/j.radonc.2013.04.006","article-title":"Clinical outcome and dosimetric parameters of chemo-radiation including MRI guided adaptive brachytherapy with tandem-ovoid applicators for cervical cancer patients: A single institution experience","volume":"107","author":"Nomden","year":"2013","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.ijrobp.2018.11.006_bib6","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1016\/j.radonc.2011.07.012","article-title":"Clinical outcome of protocol based image (MRI) guided adaptive brachytherapy combined with 3D conformal radiotherapy with or without chemotherapy in patients with locally advanced cervical cancer","volume":"100","author":"Potter","year":"2011","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.ijrobp.2018.11.006_bib7","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/j.ygyno.2014.08.027","article-title":"Improved survival of patients with cervical cancer treated with image-guided brachytherapy compared with conventional brachytherapy","volume":"135","author":"Rijkmans","year":"2014","journal-title":"Gynecol Oncol"},{"key":"10.1016\/j.ijrobp.2018.11.006_bib8","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1016\/j.radonc.2016.03.011","article-title":"Image guided brachytherapy in locally advanced cervical cancer: Improved pelvic control and survival in RetroEMBRACE, a multicenter cohort study","volume":"120","author":"Sturdza","year":"2016","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.ijrobp.2018.11.006_bib9","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/j.clon.2008.12.001","article-title":"Clinical impact of computed tomography-based image-guided brachytherapy for cervix cancer using the tandem-ring applicator\u2014the Addenbrooke's experience","volume":"21","author":"Tan","year":"2009","journal-title":"Clin Oncol (R Coll Radiol)"},{"key":"10.1016\/j.ijrobp.2018.11.006_bib10","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1016\/j.ijrobp.2014.01.032","article-title":"Manifestation pattern of early-late vaginal morbidity after definitive radiation (chemo)therapy and image-guided adaptive brachytherapy for locally advanced cervical cancer: An analysis from the EMBRACE study","volume":"89","author":"Kirchheiner","year":"2014","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2018.11.006_bib11","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1016\/j.radonc.2016.06.006","article-title":"Dose-volume effect relationships for late rectal morbidity in patients treated with chemoradiation and MRI-guided adaptive brachytherapy for locally advanced cervical cancer: Results from the prospective multicenter EMBRACE study","volume":"120","author":"Mazeron","year":"2016","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.ijrobp.2018.11.006_bib12","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1016\/j.radonc.2016.05.014","article-title":"Effect of tumor dose, volume and overall treatment time on local control after radiochemotherapy including MRI guided brachytherapy of locally advanced cervical cancer","volume":"120","author":"Tanderup","year":"2016","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.ijrobp.2018.11.006_bib13","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1016\/j.ijrobp.2014.10.053","article-title":"MRI-guided high-dose-rate intracavitary brachytherapy for treatment of cervical cancer: The University of Pittsburgh experience","volume":"91","author":"Gill","year":"2015","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2018.11.006_bib14","doi-asserted-by":"crossref","first-page":"608","DOI":"10.1016\/j.ijrobp.2017.06.010","article-title":"Magnetic resonance image guided adaptive brachytherapy in locally advanced cervical cancer: An experience from a tertiary cancer center in a low and middle income countries setting","volume":"99","author":"Mahantshetty","year":"2017","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2018.11.006_bib15","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/j.radonc.2013.01.010","article-title":"Clinical feasibility of combined intracavitary\/interstitial brachytherapy in locally advanced cervical cancer employing MRI with a tandem\/ring applicator in situ and virtual preplanning of the interstitial component","volume":"107","author":"Fokdal","year":"2013","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.ijrobp.2018.11.006_bib16","doi-asserted-by":"crossref","first-page":"624","DOI":"10.1016\/j.ijrobp.2006.01.036","article-title":"The Vienna applicator for combined intracavitary and interstitial brachytherapy of cervical cancer: Design, application, treatment planning, and dosimetric results","volume":"65","author":"Kirisits","year":"2006","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2018.11.006_bib17","doi-asserted-by":"crossref","first-page":"1424","DOI":"10.1016\/j.ijrobp.2011.04.044","article-title":"Clinical use of the Utrecht applicator for combined intracavitary\/interstitial brachytherapy treatment in locally advanced cervical cancer","volume":"15","author":"Nomden","year":"2012","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2018.11.006_bib18","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1016\/j.radonc.2016.03.020","article-title":"Image guided adaptive brachytherapy with combined intracavitary and interstitial technique improves the therapeutic ratio in locally advanced cervical cancer: Analysis from the retroEMBRACE study","volume":"120","author":"Fokdal","year":"2016","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.ijrobp.2018.11.006_bib19","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/S0029-7844(98)00146-X","article-title":"Urinary tract injuries after hysterectomy","volume":"92","author":"Harkki-Siren","year":"1998","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.ijrobp.2018.11.006_bib20","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1016\/0360-3016(94)90100-7","article-title":"Technical factors affecting morbidity in definitive irradiation for localized carcinoma of the prostate","volume":"28","author":"Perez","year":"1994","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2018.11.006_bib21","doi-asserted-by":"crossref","first-page":"814","DOI":"10.1016\/S0022-5347(01)64325-8","article-title":"Late urological complications and malignancies after curative radiotherapy for gynecological carcinomas: A retrospective analysis of 10,709 patients","volume":"158","author":"Maier","year":"1997","journal-title":"J Urol"},{"key":"10.1016\/j.ijrobp.2018.11.006_bib22","doi-asserted-by":"crossref","first-page":"836","DOI":"10.1002\/1097-0142(19950201)75:3<836::AID-CNCR2820750315>3.0.CO;2-A","article-title":"Ureteral stricture as a late complication of radiotherapy for stage IB carcinoma of the uterine cervix","volume":"75","author":"McIntyre","year":"1995","journal-title":"Cancer"},{"key":"10.1016\/j.ijrobp.2018.11.006_bib23","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/j.brachy.2014.11.013","article-title":"Ureteral stent insertion for gynecologic interstitial high-dose-rate brachytherapy","volume":"14","author":"Demanes","year":"2015","journal-title":"Brachytherapy"},{"key":"10.1016\/j.ijrobp.2018.11.006_bib24","doi-asserted-by":"crossref","first-page":"855","DOI":"10.1016\/S0360-3016(99)00111-X","article-title":"Radiation therapy morbidity in carcinoma of the uterine cervix: Dosimetric and clinical correlation","volume":"44","author":"Perez","year":"1999","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2018.11.006_bib25","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/j.radonc.2004.12.015","article-title":"Recommendations from gynaecological (GYN) GEC-ESTRO working group (I): Concepts and terms in 3D image based 3D treatment planning in cervix cancer brachytherapy with emphasis on MRI assessment of GTV and CTV","volume":"74","author":"Haie-Meder","year":"2005","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.ijrobp.2018.11.006_bib26","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.radonc.2005.11.014","article-title":"Recommendations from gynaecological (GYN) GEC ESTRO working group (II): Concepts and terms in 3D image-based treatment planning in cervix cancer brachytherapy-3D dose volume parameters and aspects of 3D image-based anatomy, radiation physics, radiobiology","volume":"78","author":"Potter","year":"2006","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.ijrobp.2018.11.006_bib27","doi-asserted-by":"crossref","DOI":"10.1016\/j.radonc.2018.05.002","article-title":"Physician assessed and patient reported urinary morbidity after radio-chemotherapy and image guided adaptive brachytherapy for locally advanced cervical cancer","author":"Fokdal","year":"2018","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.ijrobp.2018.11.006_bib28","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1038\/nrurol.2012.254","article-title":"Ureteric injury: A challenging condition to diagnose and manage","volume":"10","author":"Abboudi","year":"2013","journal-title":"Nat Rev Urol"},{"key":"10.1016\/j.ijrobp.2018.11.006_bib29","doi-asserted-by":"crossref","first-page":"960","DOI":"10.1016\/j.juro.2012.08.242","article-title":"Delayed relief of ureteral obstruction is implicated in the long-term development of renal damage and arterial hypertension in patients with unilateral ureteral injury","volume":"189","author":"Lucarelli","year":"2013","journal-title":"J Urol"},{"key":"10.1016\/j.ijrobp.2018.11.006_bib30","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1097\/MOU.0000000000000067","article-title":"Ureteral strictures and reconstruction in the cancer survivor","volume":"24","author":"Siegel","year":"2014","journal-title":"Curr Opin Urol"},{"key":"10.1016\/j.ijrobp.2018.11.006_bib31","doi-asserted-by":"crossref","first-page":"989","DOI":"10.1097\/IGC.0000000000001266","article-title":"A population-based assessment of urologic procedures and operations after surgery or pelvic radiation for cervical cancer","volume":"28","author":"Welk","year":"2018","journal-title":"Int J Gynecol Cancer"},{"key":"10.1016\/j.ijrobp.2018.11.006_bib32","article-title":"ICRU Report 89. Prescribing, recording, and reporting brachytherapy for cancer of the cervix","volume":"13","year":"2014","journal-title":"J ICRU"},{"key":"10.1016\/j.ijrobp.2018.11.006_bib33","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1016\/0360-3016(79)91211-2","article-title":"Limitations of adjunctive surgery in carcinoma of the cervix","volume":"5","author":"Rotman","year":"1979","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2018.11.006_bib34","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1002\/1097-0142(196907)24:1<77::AID-CNCR2820240110>3.0.CO;2-A","article-title":"Ureteral strictures following therapy for carcinoma of the cervix","volume":"24","author":"Shingleton","year":"1969","journal-title":"Cancer"},{"key":"10.1016\/j.ijrobp.2018.11.006_bib35","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1159\/000052529","article-title":"Nephrostomy tube or 'JJ' ureteric stent in ureteric obstruction: Assessment of patient perspectives using quality-of-life survey and utility analysis","volume":"39","author":"Joshi","year":"2001","journal-title":"Eur Urol"}],"container-title":["International Journal of Radiation Oncology*Biology*Physics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0360301618339531?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0360301618339531?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,6]],"date-time":"2025-10-06T09:44:06Z","timestamp":1759743846000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0360301618339531"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,3]]},"references-count":35,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2019,3]]}},"alternative-id":["S0360301618339531"],"URL":"https:\/\/doi.org\/10.1016\/j.ijrobp.2018.11.006","relation":{},"ISSN":["0360-3016"],"issn-type":[{"value":"0360-3016","type":"print"}],"subject":[],"published":{"date-parts":[[2019,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Risk Factors for Ureteral Stricture After Radiochemotherapy Including Image Guided Adaptive Brachytherapy in Cervical Cancer: Results From the EMBRACE Studies","name":"articletitle","label":"Article Title"},{"value":"International Journal of Radiation Oncology*Biology*Physics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ijrobp.2018.11.006","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}