{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T13:31:15Z","timestamp":1787491875884,"version":"build-2736575974"},"reference-count":33,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","redjournal.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Journal of Radiation Oncology*Biology*Physics"],"published-print":{"date-parts":[[2020,1]]},"DOI":"10.1016\/j.ijrobp.2019.10.004","type":"journal-article","created":{"date-parts":[[2019,10,14]],"date-time":"2019-10-14T20:17:49Z","timestamp":1571084269000},"page":"67-72","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":21,"title":["Short-Course 2-Dimensional Radiation Therapy in the Palliative Treatment of Esophageal Cancer in a Developing Country: A Phase II Study (Sharon Project)"],"prefix":"10.1016","volume":"106","author":[{"given":"Biniyam Tefera","family":"Deressa","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wondemagegnehu","family":"Tigeneh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Netsanet","family":"Bogale","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Milly","family":"Buwenge","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessio G.","family":"Morganti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eleonora","family":"Farina","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ijrobp.2019.10.004_bib1","first-page":"365","article-title":"Palliation of malignant dysphagia in esophageal cancer: A literature-based review","volume":"4","author":"Javle","year":"2006","journal-title":"J Support Oncol"},{"key":"10.1016\/j.ijrobp.2019.10.004_bib2","first-page":"e2507","article-title":"Epidemiology and survival of esophageal cancer patients in an American cohort","volume":"10","author":"Nassri","year":"2018","journal-title":"Cureus"},{"key":"10.1016\/j.ijrobp.2019.10.004_bib3","doi-asserted-by":"crossref","first-page":"5679","DOI":"10.3748\/wjg.v18.i40.5679","article-title":"Multimodality approach for locally advanced esophageal cancer","volume":"18","author":"Almhanna","year":"2012","journal-title":"World J Gastroenterol"},{"key":"10.1016\/j.ijrobp.2019.10.004_bib4","doi-asserted-by":"crossref","first-page":"52","DOI":"10.3389\/fonc.2012.00052","article-title":"Locally advanced cancer of the esophagus, current treatment strategies, and future directions","volume":"2","author":"Rahma","year":"2012","journal-title":"Front Oncol"},{"key":"10.1016\/j.ijrobp.2019.10.004_bib5","first-page":"347","article-title":"Definitive, preoperative, and palliative radiation therapy of esophageal cancer","volume":"31","author":"Fokas","year":"2015","journal-title":"Viszeralmedizin"},{"key":"10.1016\/j.ijrobp.2019.10.004_bib6","doi-asserted-by":"crossref","first-page":"125","DOI":"10.7150\/jca.13655","article-title":"Survival and symptom relief after palliative radiotherapy for esophageal cancer","volume":"7","author":"Welsch","year":"2016","journal-title":"J Cancer"},{"key":"10.1016\/j.ijrobp.2019.10.004_bib7","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1159\/000099034","article-title":"Quality of life in patients with esophageal and gastric cancer: An overview","volume":"70","author":"Conroy","year":"2006","journal-title":"Oncology"},{"key":"10.1016\/j.ijrobp.2019.10.004_bib8","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1016\/j.thorsurg.2013.07.011","article-title":"Quality of life in patients with esophageal cancer","volume":"23","author":"Darling","year":"2013","journal-title":"Thorac Surg Clin"},{"key":"10.1016\/j.ijrobp.2019.10.004_bib9","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/j.critrevonc.2017.12.019","article-title":"ECCO essential requirements for quality cancer care: Esophageal and gastric cancer","volume":"122","author":"Allum","year":"2018","journal-title":"Crit Rev Oncol Hematol"},{"key":"10.1016\/j.ijrobp.2019.10.004_bib10","first-page":"183","article-title":"The experience of dysphagia and its effect on the quality of life of patients with esophageal cancer","volume":"12","author":"Watt","year":"2003","journal-title":"Eur J Cancer Care (Engl)"},{"key":"10.1016\/j.ijrobp.2019.10.004_bib11","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1046\/j.1442-2050.2001.00168.x","article-title":"Best palliation in esophageal: Surgery, stenting, radiation, or what?","volume":"14","author":"Frenken","year":"2001","journal-title":"Dis Esophagus"},{"key":"10.1016\/j.ijrobp.2019.10.004_bib12","first-page":"CD005048","article-title":"Interventions for dysphagia in esophageal cancer","volume":"10","author":"Dai","year":"2014","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.ijrobp.2019.10.004_bib13","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1016\/j.radonc.2016.12.034","article-title":"Brachytherapy for the palliation of dysphagia owing to esophageal cancer: A systematic review and meta-analysis of prospective studies","volume":"122","author":"Fuccio","year":"2017","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.ijrobp.2019.10.004_bib14","first-page":"118","article-title":"Palliative concurrent chemoradiotherapy in locally advanced and metastatic esophageal\u00a0cancer patients with dysphagia","volume":"2","author":"Akl","year":"2013","journal-title":"Ann Palliat Med"},{"key":"10.1016\/j.ijrobp.2019.10.004_bib15","doi-asserted-by":"crossref","first-page":"4223","DOI":"10.1245\/s10434-012-2459-3","article-title":"Esophageal stenting and radiotherapy: A multimodal approach for the palliation of symptomatic malignant dysphagia","volume":"19","author":"Rueth","year":"2012","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.ijrobp.2019.10.004_bib16","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1016\/j.radonc.2015.10.023","article-title":"Palliative radiotherapy fractionation schedules prescribed are dependent on the distance a patient travels to receive treatment","volume":"117","author":"Barnes","year":"2015","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.ijrobp.2019.10.004_bib17","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1016\/j.prro.2011.12.002","article-title":"Palliative radiotherapy in patients with esophageal carcinoma: A retrospective review","volume":"2","author":"Murray","year":"2012","journal-title":"Pract Radiat Oncol"},{"key":"10.1016\/j.ijrobp.2019.10.004_bib18","doi-asserted-by":"crossref","first-page":"1076","DOI":"10.1007\/s10147-018-1324-1","article-title":"Palliative radiotherapy and chemoradiotherapy in stage IVA\/B esophageal cancer patients with dysphagia","volume":"23","author":"Kawamoto","year":"2018","journal-title":"Int J Clin Oncol"},{"key":"10.1016\/j.ijrobp.2019.10.004_bib19","doi-asserted-by":"crossref","first-page":"e627","DOI":"10.1016\/j.ijrobp.2011.10.081","article-title":"Short course accelerated radiation therapy (SHARON) in palliative treatment of advanced pelvic malignancies: a phase I study","volume":"83","author":"Caravatta","year":"2012","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2019.10.004_bib20","first-page":"2409","article-title":"Phase I-II study of short-course accelerated radiotherapy (SHARON) for palliation in head and neck cancer","volume":"38","author":"Farina","year":"2018","journal-title":"Anticancer Res"},{"key":"10.1016\/j.ijrobp.2019.10.004_bib21","doi-asserted-by":"crossref","first-page":"e463","DOI":"10.1016\/j.ijrobp.2012.06.023","article-title":"A phase I study of short-course accelerated whole brain radiation therapy for multiple brain metastases","volume":"84","author":"Caravatta","year":"2012","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2019.10.004_bib22","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1097\/COC.0b013e3182a0e826","article-title":"Results of a phase II study of short-course accelerated radiation therapy (SHARON) for multiple brain metastases","volume":"38","author":"Caravatta","year":"2015","journal-title":"Am J Clin Oncol"},{"key":"10.1016\/j.ijrobp.2019.10.004_bib23","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1007\/s10585-018-9931-9","article-title":"Short-course regimen of palliative radiotherapy in complicated bone metastases: a phase i-ii study (SHARON Project)","volume":"35","author":"Capuccini","year":"2018","journal-title":"Clin Exp Metastasis"},{"key":"10.1016\/j.ijrobp.2019.10.004_bib24","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1007\/s10585-018-9942-6","article-title":"Radiotherapy in palliation of thoracic tumors: a phase I-II study (SHARON project)","volume":"35","author":"Farina","year":"2018","journal-title":"Clin Exp Metastasis"},{"key":"10.1016\/j.ijrobp.2019.10.004_bib25","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1016\/j.jgo.2018.01.004","article-title":"Short course accelerated radiation therapy (SHARON) in palliative treatment of advanced solid cancer in older patients: a pooled analysis","volume":"9","author":"Farina","year":"2018","journal-title":"J Geriatr Oncol"},{"key":"10.1016\/j.ijrobp.2019.10.004_bib26","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1016\/j.radonc.2010.09.001","article-title":"Adding external beam to intra-luminal brachytherapy improves palliation in obstructive squamous cell esophageal cancer: A prospective multi-centre randomized trial of the International Atomic Energy Agency","volume":"97","author":"Rosenblatt","year":"2010","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.ijrobp.2019.10.004_bib27","first-page":"1375","article-title":"Randomized phase II clinical trials","volume":"69","author":"Simon","year":"1985","journal-title":"Cancer Treatment Rep"},{"key":"10.1016\/j.ijrobp.2019.10.004_bib28","series-title":"Principles and Practice of Radiation Oncology","first-page":"64","article-title":"Biological basis of radiation therapy","author":"Withers","year":"1992"},{"key":"10.1016\/j.ijrobp.2019.10.004_bib29","doi-asserted-by":"crossref","first-page":"1341","DOI":"10.1016\/0360-3016(95)00060-C","article-title":"Toxicity criteria of the Radiation Therapy Oncology Group (RTOG) and the European Organization for Research and Treatment of Cancer (EORTC)","volume":"31","author":"Cox","year":"1995","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2019.10.004_bib30","first-page":"85","article-title":"Challenges of making radiotherapy accessible in developing countries","author":"Samiei","year":"2013","journal-title":"Cancer Control"},{"key":"10.1016\/j.ijrobp.2019.10.004_bib31","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/j.clon.2007.10.003","article-title":"A phase I\/II study to evaluate the toxicity and efficacy of accelerated fractionation radiotherapy for the palliation of dysphagia from carcinoma of the oesophagus","volume":"20","author":"Kassam","year":"2008","journal-title":"Clin Oncol (R Coll Radiol)"},{"key":"10.1016\/j.ijrobp.2019.10.004_bib32","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1016\/S0360-3016(01)01822-3","article-title":"Palliation of advanced\/recurrent esophageal carcinoma with high-dose-rate brachytherapy","volume":"52","author":"Sharma","year":"2002","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2019.10.004_bib33","doi-asserted-by":"crossref","first-page":"e0184784","DOI":"10.1371\/journal.pone.0184784","article-title":"Complications of stent placement in patients with esophageal cancer: A systematic review and network meta-analysis","volume":"12","author":"Doosti-Irani","year":"2017","journal-title":"PLoS One"}],"container-title":["International Journal of Radiation Oncology*Biology*Physics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0360301619338714?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0360301619338714?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,6]],"date-time":"2025-10-06T09:45:37Z","timestamp":1759743937000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0360301619338714"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,1]]},"references-count":33,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2020,1]]}},"alternative-id":["S0360301619338714"],"URL":"https:\/\/doi.org\/10.1016\/j.ijrobp.2019.10.004","relation":{},"ISSN":["0360-3016"],"issn-type":[{"value":"0360-3016","type":"print"}],"subject":[],"published":{"date-parts":[[2020,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Short-Course 2-Dimensional Radiation Therapy in the Palliative Treatment of Esophageal Cancer in a Developing Country: A Phase II Study (Sharon Project)","name":"articletitle","label":"Article Title"},{"value":"International Journal of Radiation Oncology*Biology*Physics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ijrobp.2019.10.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}