{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T02:24:55Z","timestamp":1792808695215,"version":"4.5.0"},"reference-count":45,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T00:00:00Z","timestamp":1717200000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T00:00:00Z","timestamp":1717200000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T00:00:00Z","timestamp":1717200000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T00:00:00Z","timestamp":1717200000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T00:00:00Z","timestamp":1717200000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T00:00:00Z","timestamp":1717200000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T00:00:00Z","timestamp":1717200000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","redjournal.org","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Journal of Radiation Oncology*Biology*Physics"],"published-print":{"date-parts":[[2024,6]]},"DOI":"10.1016\/j.ijrobp.2023.07.025","type":"journal-article","created":{"date-parts":[[2023,9,29]],"date-time":"2023-09-29T20:21:50Z","timestamp":1696018910000},"page":"640-654","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":34,"title":["Risk of Subsequent Neoplasms in Childhood Cancer Survivors After Radiation Therapy: A PENTEC Comprehensive Review"],"prefix":"10.1016","volume":"119","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6851-7653","authenticated-orcid":false,"given":"Dana L.","family":"Casey","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ivan R.","family":"Vogelius","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N. Patrik","family":"Brodin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenneth B.","family":"Roberts","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michele","family":"Avanzo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Janaki","family":"Moni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Constance","family":"Owens","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C\u00e9cile M.","family":"Ronckers","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Louis S.","family":"Constine","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Soren M.","family":"Bentzen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arthur","family":"Olch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ijrobp.2023.07.025_bib0001","unstructured":"Howlader N, Noone AM, Krapcho M, et al, SEER Cancer Statistics Review (CSR) 1975-2016. Bethesda, MD: National Cancer Institute; updated September 5, 2019."},{"key":"10.1016\/j.ijrobp.2023.07.025_bib0002","doi-asserted-by":"crossref","first-page":"7","DOI":"10.3322\/caac.21654","article-title":"Cancer statistics, 2021","volume":"71","author":"Siegel","year":"2021","journal-title":"CA Cancer J Clin"},{"key":"10.1016\/j.ijrobp.2023.07.025_bib0003","doi-asserted-by":"crossref","first-page":"2356","DOI":"10.1200\/JCO.2008.21.1920","article-title":"Second neoplasms in survivors of childhood cancer: Findings from the Childhood Cancer Survivor Study cohort","volume":"27","author":"Meadows","year":"2009","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.ijrobp.2023.07.025_bib0004","doi-asserted-by":"crossref","first-page":"2328","DOI":"10.1200\/JCO.2008.21.1425","article-title":"Late mortality among 5-year survivors of childhood cancer: A summary from the Childhood Cancer Survivor Study","volume":"27","author":"Armstrong","year":"2009","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.ijrobp.2023.07.025_bib0005","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1002\/1097-0142(194805)1:1<3::AID-CNCR2820010103>3.0.CO;2-7","article-title":"Sarcoma arising in irradiated bone: Report of 11 cases","volume":"1","author":"Cahan","year":"1948","journal-title":"Cancer"},{"key":"10.1016\/j.ijrobp.2023.07.025_bib0006","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1667\/RR14492.1","article-title":"Solid cancer incidence among the Life Span Study of Atomic Bomb Survivors: 1958-2009","volume":"187","author":"Grant","year":"2017","journal-title":"Radiat Res"},{"key":"10.1016\/j.ijrobp.2023.07.025_bib0007","article-title":"Risk of digestive cancers in a cohort of 69 460 five-year survivors of childhood cancer in Europe: the PanCareSurFup study","author":"Reulen","year":"2020","journal-title":"Gut"},{"key":"10.1016\/j.ijrobp.2023.07.025_bib0008","doi-asserted-by":"crossref","first-page":"1809","DOI":"10.1002\/cncr.29841","article-title":"Therapeutic radiation and the potential risk of second malignancies","volume":"122","author":"Kamran","year":"2016","journal-title":"Cancer"},{"key":"10.1016\/j.ijrobp.2023.07.025_bib0009","doi-asserted-by":"crossref","first-page":"S17","DOI":"10.2307\/3578892","article-title":"Cancer incidence in atomic bomb survivors. Part II: Solid tumors, 1958-1987","volume":"137","author":"Thompson","year":"1994","journal-title":"Radiat Res"},{"key":"10.1016\/j.ijrobp.2023.07.025_bib0010","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1667\/RR1801.1","article-title":"Ionizing radiation and leukemia mortality among Japanese atomic bomb survivors, 1950-2000","volume":"172","author":"Richardson","year":"2009","journal-title":"Radiat Res"},{"key":"10.1016\/j.ijrobp.2023.07.025_bib0011","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.ijrobp.2006.01.027","article-title":"Intensity-modulated radiation therapy, protons, and the risk of second cancers","volume":"65","author":"Hall","year":"2006","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2023.07.025_bib0012","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1200\/JCO.2005.06.225","article-title":"Malignant breast tumors after radiotherapy for a first cancer during childhood","volume":"23","author":"Guibout","year":"2005","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.ijrobp.2023.07.025_bib0013","doi-asserted-by":"crossref","first-page":"2336","DOI":"10.1056\/NEJMoa1508054","article-title":"Germline mutations in predisposition genes in pediatric cancer","volume":"373","author":"Zhang","year":"2015","journal-title":"N Engl J Med"},{"key":"10.1016\/j.ijrobp.2023.07.025_bib0014","doi-asserted-by":"crossref","first-page":"950","DOI":"10.1200\/JCO.2011.37.0239","article-title":"Variation of second cancer risk by family history of retinoblastoma among long-term survivors","volume":"30","author":"Kleinerman","year":"2012","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.ijrobp.2023.07.025_bib0015","doi-asserted-by":"crossref","first-page":"3284","DOI":"10.1200\/JCO.2013.54.7844","article-title":"Risk of subsequent malignant neoplasms in long-term hereditary retinoblastoma survivors after chemotherapy and radiotherapy","volume":"32","author":"Wong","year":"2014","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.ijrobp.2023.07.025_bib0016","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1016\/j.ijrobp.2012.09.001","article-title":"Second solid cancers after radiation therapy: A systematic review of the epidemiologic studies of the radiation dose-response relationship","volume":"86","author":"Berrington de Gonzalez","year":"2013","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2023.07.025_bib0017","doi-asserted-by":"crossref","first-page":"800","DOI":"10.1016\/j.ijrobp.2015.11.046","article-title":"Radiation-related new primary solid cancers in the Childhood Cancer Survivor Study: Comparative radiation dose response and modification of treatment effects","volume":"94","author":"Inskip","year":"2016","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2023.07.025_bib0018","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1667\/RR15308.1","article-title":"Comparison of radiation dose reconstruction methods to investigate late adverse effects of radiotherapy for childhood cancer: A report from the Childhood Cancer Survivor Study","volume":"193","author":"Schonfeld","year":"2020","journal-title":"Radiat Res"},{"key":"10.1016\/j.ijrobp.2023.07.025_bib0019","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.1016\/j.jclinepi.2009.06.006","article-title":"The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: Explanation and elaboration","volume":"62","author":"Liberati","year":"2009","journal-title":"J Clin Epidemiol"},{"key":"10.1016\/j.ijrobp.2023.07.025_bib0020","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1137\/0111030","article-title":"An algorithm for least-squares estimation of non linear parameters","volume":"11","author":"Marquardt","year":"1963","journal-title":"J Soc Indust Appl Math"},{"key":"10.1016\/j.ijrobp.2023.07.025_bib0021","unstructured":"The Cochrane Collaboration. Review Manager (RevMan), version 5.4.1. 2020."},{"key":"10.1016\/j.ijrobp.2023.07.025_bib0022","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1093\/neuonc\/noy124","article-title":"Risk of benign meningioma after childhood cancer in the DCOG-LATER cohort: Contributions of radiation dose, exposed cranial volume, and age","volume":"21","author":"Kok","year":"2019","journal-title":"Neuro Oncol"},{"key":"10.1016\/j.ijrobp.2023.07.025_bib0023","unstructured":"Lar\u00f8nningen S FJ, Beydogan H, Bray F, et al. Storm HH NORDCAN: Cancer Incidence, Mortality, Prevalence and Survival in the Nordic Countries, version 9.2. Cancer Registry of Norway. Association of the Nordic Cancer Registries. 2022."},{"key":"10.1016\/j.ijrobp.2023.07.025_bib0024","doi-asserted-by":"crossref","first-page":"725","DOI":"10.3109\/02841861003782017","article-title":"NORDCAN\u2014A Nordic tool for cancer information, planning, quality control and research","volume":"49","author":"Engholm","year":"2010","journal-title":"Acta Oncol"},{"key":"10.1016\/j.ijrobp.2023.07.025_bib0025","doi-asserted-by":"crossref","first-page":"1528","DOI":"10.1093\/jnci\/djj411","article-title":"New primary neoplasms of the central nervous system in survivors of childhood cancer: A report from the Childhood Cancer Survivor Study","volume":"98","author":"Neglia","year":"2006","journal-title":"J Natl Cancer Inst"},{"key":"10.1016\/j.ijrobp.2023.07.025_bib0026","doi-asserted-by":"crossref","first-page":"814","DOI":"10.1001\/jama.2017.0693","article-title":"Temporal trends in treatment and subsequent neoplasm risk among 5-year survivors of childhood cancer, 1970-2015","volume":"317","author":"Turcotte","year":"2017","journal-title":"JAMA"},{"key":"10.1016\/j.ijrobp.2023.07.025_bib0027","doi-asserted-by":"crossref","first-page":"1277","DOI":"10.1007\/s00432-015-1920-7","article-title":"Meningiomas after cranial radiotherapy for childhood cancer: A single institution experience","volume":"141","author":"Felicetti","year":"2015","journal-title":"J Cancer Res Clin Oncol"},{"key":"10.1016\/j.ijrobp.2023.07.025_bib0028","doi-asserted-by":"crossref","first-page":"3761","DOI":"10.1200\/JCO.1998.16.12.3761","article-title":"Secondary brain tumors in children treated for acute lymphoblastic leukemia at St Jude Children's Research Hospital","volume":"16","author":"Walter","year":"1998","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.ijrobp.2023.07.025_bib0029","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1158\/1055-9965.EPI-20-0735","article-title":"Risk factors of subsequent central nervous system tumors after childhood and adolescent cancers: Findings from the French Childhood Cancer Survivor Study","volume":"30","author":"Journy","year":"2021","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"10.1016\/j.ijrobp.2023.07.025_bib0030","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1002\/(SICI)1097-0215(19981029)78:3<269::AID-IJC1>3.0.CO;2-T","article-title":"Risks of brain tumour following treatment for cancer in childhood: Modification by genetic factors, radiotherapy and chemotherapy","volume":"78","author":"Little","year":"1998","journal-title":"Int J Cancer"},{"key":"10.1016\/j.ijrobp.2023.07.025_bib0031","doi-asserted-by":"crossref","first-page":"5287","DOI":"10.1200\/JCO.2009.27.0090","article-title":"Population-based risks of CNS tumors in survivors of childhood cancer: The British Childhood Cancer Survivor Study","volume":"28","author":"Taylor","year":"2010","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.ijrobp.2023.07.025_bib0032","doi-asserted-by":"crossref","first-page":"1083","DOI":"10.1093\/jnci\/djq238","article-title":"Subsequent neoplasms in 5-year survivors of childhood cancer: The Childhood Cancer Survivor Study","volume":"102","author":"Friedman","year":"2010","journal-title":"J Natl Cancer Inst"},{"key":"10.1016\/j.ijrobp.2023.07.025_bib0033","doi-asserted-by":"crossref","first-page":"2030","DOI":"10.1210\/jc.2013-4159","article-title":"Growth hormone exposure as a risk factor for the development of subsequent neoplasms of the central nervous system: A report from the Childhood Cancer Survivor Study","volume":"99","author":"Patterson","year":"2014","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.ijrobp.2023.07.025_bib0034","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1016\/j.ejca.2006.10.004","article-title":"Risk of second malignancies in long-term survivors of childhood cancer","volume":"43","author":"Cardous-Ubbink","year":"2007","journal-title":"Eur J Cancer"},{"key":"10.1016\/j.ijrobp.2023.07.025_bib0035","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1016\/j.ijrobp.2011.11.022","article-title":"Risk factors associated with secondary sarcomas in childhood cancer survivors: A report from the childhood cancer survivor study","volume":"84","author":"Henderson","year":"2012","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2023.07.025_bib0036","doi-asserted-by":"crossref","first-page":"2235","DOI":"10.1158\/1055-9965.EPI-21-0250","article-title":"Lung cancer as a subsequent malignant neoplasm in survivors of childhood cancer","volume":"30","author":"Ghosh","year":"2021","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"10.1016\/j.ijrobp.2023.07.025_bib0037","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1093\/jnci\/94.3.182","article-title":"Lung cancer following chemotherapy and radiotherapy for Hodgkin's disease","volume":"94","author":"Travis","year":"2002","journal-title":"J Natl Cancer Inst"},{"key":"10.1016\/j.ijrobp.2023.07.025_bib0038","doi-asserted-by":"crossref","first-page":"1079","DOI":"10.1093\/annonc\/mdh273","article-title":"Solid tumors in patients treated for Hodgkin's disease: A report from the German Hodgkin Lymphoma Study Group","volume":"15","author":"Behringer","year":"2004","journal-title":"Ann Oncol"},{"key":"10.1016\/j.ijrobp.2023.07.025_bib0039","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1007\/s00408-012-9418-4","article-title":"Increased risk of second lung cancer in Hodgkin's lymphoma survivors: A meta-analysis","volume":"191","author":"Ibrahim","year":"2013","journal-title":"Lung"},{"key":"10.1016\/j.ijrobp.2023.07.025_bib0041","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1002\/pbc.25285","article-title":"Second cancer risk in childhood cancer survivors treated with intensity-modulated radiation therapy (IMRT)","volume":"62","author":"Casey","year":"2015","journal-title":"Pediatr Blood Cancer"},{"key":"10.1016\/j.ijrobp.2023.07.025_bib0042","doi-asserted-by":"crossref","first-page":"e29600","DOI":"10.1002\/pbc.29600","article-title":"Second cancer risk in childhood cancer survivors treated with intensity-modulated radiation therapy: An updated analysis of more than 10 years of follow-up","volume":"69","author":"Tringale","year":"2022","journal-title":"Pediatr Blood Cancer"},{"key":"10.1016\/j.ijrobp.2023.07.025_bib0043","doi-asserted-by":"crossref","first-page":"3560","DOI":"10.1002\/cncr.32938","article-title":"Second cancer risk after primary cancer treatment with three-dimensional conformal, intensity-modulated, or proton beam radiation therapy","volume":"126","author":"Xiang","year":"2020","journal-title":"Cancer"},{"key":"10.1016\/j.ijrobp.2023.07.025_bib0044","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.ijrobp.2013.05.016","article-title":"Subsequent malignancies after photon versus proton radiation therapy","volume":"87","author":"Bekelman","year":"2013","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2023.07.025_bib0045","doi-asserted-by":"crossref","first-page":"833","DOI":"10.1056\/NEJMoa1510795","article-title":"Reduction in late mortality among 5-year survivors of childhood cancer","volume":"374","author":"Armstrong","year":"2016","journal-title":"N Engl J Med"},{"key":"10.1016\/j.ijrobp.2023.07.025_bib0046","doi-asserted-by":"crossref","first-page":"941","DOI":"10.1038\/nm.2407","article-title":"Variants at 6q21 implicate PRDM1 in the etiology of therapy-induced second malignancies after Hodgkin's lymphoma","volume":"17","author":"Best","year":"2011","journal-title":"Nat Med"}],"container-title":["International Journal of Radiation Oncology*Biology*Physics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S036030162307685X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S036030162307685X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,6,6]],"date-time":"2024-06-06T14:05:47Z","timestamp":1717682747000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S036030162307685X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,6]]},"references-count":45,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2024,6]]}},"alternative-id":["S036030162307685X"],"URL":"https:\/\/doi.org\/10.1016\/j.ijrobp.2023.07.025","relation":{},"ISSN":["0360-3016"],"issn-type":[{"value":"0360-3016","type":"print"}],"subject":[],"published":{"date-parts":[[2024,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Risk of Subsequent Neoplasms in Childhood Cancer Survivors After Radiation Therapy: A PENTEC Comprehensive Review","name":"articletitle","label":"Article Title"},{"value":"International Journal of Radiation Oncology*Biology*Physics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ijrobp.2023.07.025","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}