{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T01:27:16Z","timestamp":1778549236626,"version":"3.51.4"},"reference-count":24,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100004325","name":"AstraZeneca","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004325","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004326","name":"Bayer","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004326","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100005481","name":"New York University Grossman School of Medicine","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100005481","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","redjournal.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Journal of Radiation Oncology*Biology*Physics"],"published-print":{"date-parts":[[2025,8]]},"DOI":"10.1016\/j.ijrobp.2024.12.027","type":"journal-article","created":{"date-parts":[[2025,1,7]],"date-time":"2025-01-07T03:11:24Z","timestamp":1736219484000},"page":"1128-1139","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"title":["Phase 1-2 Study of Prone Hypofractionated Accelerated Breast and Nodal Intensity Modulated Radiation Therapy"],"prefix":"10.1016","volume":"122","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1068-9449","authenticated-orcid":false,"given":"Juhi M.","family":"Purswani","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Olivier","family":"Maisonet","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julie","family":"Xiao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jose R.","family":"Teruel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christine","family":"Hitchen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaochun","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Judith D.","family":"Goldberg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carmen A.","family":"Perez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Silvia C.","family":"Formenti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naamit K.","family":"Gerber","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ijrobp.2024.12.027_bib0001","doi-asserted-by":"crossref","first-page":"2127","DOI":"10.1016\/S0140-6736(14)60488-8","article-title":"Effect of radiotherapy after mastectomy and axillary surgery on 10-year recurrence and 20-year breast cancer mortality: Meta-analysis of individual patient data for 8135 women in 22 randomised trials","volume":"383","author":"McGale","year":"2014","journal-title":"Lancet"},{"key":"10.1016\/j.ijrobp.2024.12.027_bib0002","doi-asserted-by":"crossref","first-page":"1707","DOI":"10.1016\/S0140-6736(11)61629-2","article-title":"Effect of radiotherapy after breast-conserving surgery on 10-year recurrence and 15-year breast cancer death: Meta-analysis of individual patient data for 10,801 women in 17 randomised trials","volume":"378","author":"Darby","year":"2011","journal-title":"Lancet"},{"key":"10.1016\/j.ijrobp.2024.12.027_bib0003","doi-asserted-by":"crossref","first-page":"931","DOI":"10.1001\/jamaoncol.2015.2666","article-title":"Acute and short-term toxic effects of conventionally fractionated vs hypofractionated whole-breast irradiation: A randomized clinical trial","volume":"1","author":"Shaitelman","year":"2015","journal-title":"JAMA Oncol"},{"key":"10.1016\/j.ijrobp.2024.12.027_bib0004","doi-asserted-by":"crossref","first-page":"e81","DOI":"10.1016\/j.prro.2015.10.022","article-title":"Breast, chest wall, and nodal irradiation with prone set-up: Results of a hypofractionated trial with a median follow-up of 35 months","volume":"6","author":"Shin","year":"2016","journal-title":"Pract Radiat Oncol"},{"key":"10.1016\/j.ijrobp.2024.12.027_bib0005","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1016\/j.ijrobp.2008.04.040","article-title":"Coverage of axillary lymph nodes in supine vs. prone breast radiotherapy","volume":"73","author":"Alonso-Basanta","year":"2009","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2024.12.027_bib0006","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1007\/s13566-020-00433-z","article-title":"Whole breast irradiation with high tangents in the prone position","volume":"9","author":"Shaikh","year":"2020","journal-title":"J Radiat Oncol"},{"key":"10.1016\/j.ijrobp.2024.12.027_bib0007","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1097\/COC.0b013e3181dbb9c1","article-title":"A dosimetric comparison between the supine and prone positions for three-field intact breast radiotherapy","volume":"34","author":"Gielda","year":"2011","journal-title":"Am J Clin Oncol"},{"key":"10.1016\/j.ijrobp.2024.12.027_bib0008","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1111\/j.1754-9485.2012.02389.x","article-title":"A prone technique for treatment of the breast, supraclavicular and axillary nodes","volume":"56","author":"Mason","year":"2012","journal-title":"J Med Imaging Radiat Oncol"},{"key":"10.1016\/j.ijrobp.2024.12.027_bib0009","doi-asserted-by":"crossref","first-page":"943","DOI":"10.1016\/j.ijrobp.2020.03.049","article-title":"Acute toxicity and quality of life of hypofractionated radiation therapy for breast cancer","volume":"107","author":"Arsenault","year":"2020","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2024.12.027_bib0010","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1016\/j.prro.2024.04.016","article-title":"A radiation therapy contouring atlas for delineation of the level I and II axillae in the prone position: A single-institution experience","volume":"14","author":"Purswani","year":"2024","journal-title":"Pract Radiat Oncol"},{"key":"10.1016\/j.ijrobp.2024.12.027_bib0011","doi-asserted-by":"crossref","first-page":"2037","DOI":"10.1200\/JCO.2016.70.7158","article-title":"Hypofractionated postmastectomy radiation therapy is safe and effective: First results from a prospective phase II trial","volume":"35","author":"Khan","year":"2017","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.ijrobp.2024.12.027_bib0012","doi-asserted-by":"crossref","first-page":"1083","DOI":"10.1016\/S1470-2045(23)00388-1","article-title":"Conventional versus hypofractionated postmastectomy proton radiotherapy in the USA (MC1631): A randomised phase 2 trial","volume":"24","author":"Mutter","year":"2023","journal-title":"Lancet Oncol"},{"key":"10.1016\/j.ijrobp.2024.12.027_bib0013","doi-asserted-by":"crossref","first-page":"1370","DOI":"10.1001\/jamaoncol.2024.2652","article-title":"Hypofractionated vs conventionally fractionated postmastectomy radiation after implant-based reconstruction: A randomized clinical trial","volume":"10","author":"Wong","year":"2024","journal-title":"JAMA Oncol"},{"key":"10.1016\/j.ijrobp.2024.12.027_bib0014","doi-asserted-by":"crossref","first-page":"987","DOI":"10.1056\/NEJMoa1209825","article-title":"Risk of ischemic heart disease in women after radiotherapy for breast cancer","volume":"368","author":"Darby","year":"2013","journal-title":"N Engl J Med"},{"key":"10.1016\/j.ijrobp.2024.12.027_bib0015","doi-asserted-by":"crossref","first-page":"1641","DOI":"10.1200\/JCO.2016.72.0722","article-title":"Estimating the risks of breast cancer radiotherapy: Evidence from modern radiation doses to the lungs and heart and from previous randomized trials","volume":"35","author":"Taylor","year":"2017","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.ijrobp.2024.12.027_bib0016","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/j.radonc.2011.09.008","article-title":"Comparison of three-dimensional versus intensity-modulated radiotherapy techniques to treat breast and axillary level III and supraclavicular nodes in a prone versus supine position","volume":"102","author":"Sethi","year":"2012","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.ijrobp.2024.12.027_bib0017","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/0167-8140(90)90057-4","article-title":"Radiation-induced brachial plexus injury: Follow-up of two different fractionation schedules","volume":"18","author":"Powell","year":"1990","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.ijrobp.2024.12.027_bib0018","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1080\/02841860500371907","article-title":"Radiation-induced brachial plexopathy and hypofractionated regimens in adjuvant irradiation of patients with breast cancer\u2013A review","volume":"45","author":"Ga\u0142ecki","year":"2006","journal-title":"Acta Oncol"},{"key":"10.1016\/j.ijrobp.2024.12.027_bib0019","doi-asserted-by":"crossref","first-page":"1362","DOI":"10.1016\/j.ijrobp.2008.03.004","article-title":"Development and validation of a standardized method for contouring the brachial plexus: Preliminary dosimetric analysis among patients treated with IMRT for head-and-neck cancer","volume":"72","author":"Hall","year":"2008","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2024.12.027_bib0020","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1056\/NEJMoa1415340","article-title":"Regional nodal irradiation in early-stage breast cancer","volume":"373","author":"Whelan","year":"2015","journal-title":"N Engl J Med"},{"key":"10.1016\/j.ijrobp.2024.12.027_bib0021","doi-asserted-by":"crossref","first-page":"1602","DOI":"10.1016\/S1470-2045(20)30472-1","article-title":"Internal mammary and medial supraclavicular lymph node chain irradiation in stage I-III breast cancer (EORTC 22922\/10925): 15-year results of a randomised, phase 3 trial","volume":"21","author":"Poortmans","year":"2020","journal-title":"Lancet Oncol"},{"key":"10.1016\/j.ijrobp.2024.12.027_bib0022","doi-asserted-by":"crossref","first-page":"1303","DOI":"10.1016\/S1470-2045(14)70460-7","article-title":"Radiotherapy or surgery of the axilla after a positive sentinel node in breast cancer (EORTC 10981-22023 AMAROS): A randomised, multicentre, open-label, phase 3 non-inferiority trial","volume":"15","author":"Donker","year":"2014","journal-title":"Lancet Oncol"},{"key":"10.1016\/j.ijrobp.2024.12.027_bib0023","doi-asserted-by":"crossref","first-page":"918","DOI":"10.1001\/jama.2017.11470","article-title":"Effect of axillary dissection vs no axillary dissection on 10-year overall survival among women with invasive breast cancer and sentinel node metastasis: The ACOSOG Z0011 (Alliance) randomized clinical trial","volume":"318","author":"Giuliano","year":"2017","journal-title":"JAMA"},{"key":"10.1016\/j.ijrobp.2024.12.027_bib0024","first-page":"367","article-title":"Radiation dose to the nodal regions during prone versus supine breast irradiation","volume":"10","author":"Csenki","year":"2014","journal-title":"Ther Clin Risk Manag"}],"container-title":["International Journal of Radiation Oncology*Biology*Physics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0360301625000045?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0360301625000045?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,4]],"date-time":"2025-11-04T22:51:03Z","timestamp":1762296663000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0360301625000045"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8]]},"references-count":24,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2025,8]]}},"alternative-id":["S0360301625000045"],"URL":"https:\/\/doi.org\/10.1016\/j.ijrobp.2024.12.027","relation":{},"ISSN":["0360-3016"],"issn-type":[{"value":"0360-3016","type":"print"}],"subject":[],"published":{"date-parts":[[2025,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Phase 1-2 Study of Prone Hypofractionated Accelerated Breast and Nodal Intensity Modulated Radiation Therapy","name":"articletitle","label":"Article Title"},{"value":"International Journal of Radiation Oncology*Biology*Physics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ijrobp.2024.12.027","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}