{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,18]],"date-time":"2026-07-18T06:54:54Z","timestamp":1784357694440,"version":"3.55.0"},"reference-count":39,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","award":["NRF-2023R1A2C3003782"],"award-info":[{"award-number":["NRF-2023R1A2C3003782"]}],"id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","redjournal.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Journal of Radiation Oncology*Biology*Physics"],"published-print":{"date-parts":[[2025,11]]},"DOI":"10.1016\/j.ijrobp.2025.05.062","type":"journal-article","created":{"date-parts":[[2025,5,25]],"date-time":"2025-05-25T10:10:03Z","timestamp":1748167803000},"page":"753-764","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"title":["Relationship of Immediate Breast Reconstruction and the Development of Lymphedema in Breast Cancer Patients With Radiation Therapy"],"prefix":"10.1016","volume":"123","author":[{"given":"Soon Woo","family":"Hong","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eun-Kyu","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hee-Chul","family":"Shin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jaewon","family":"Beom","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jae-Young","family":"Lim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Koung Jin","family":"Suh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jee Hyun","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chan Yeong","family":"Heo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyubo","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9838-5399","authenticated-orcid":false,"given":"In Ah","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ijrobp.2025.05.062_bib0001","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1097\/SLA.0000000000003491","article-title":"Risk of lymphedema following contemporary treatment for breast cancer: An analysis of 7617 consecutive patients from a multidisciplinary perspective","volume":"274","author":"Byun","year":"2021","journal-title":"Ann Surg"},{"key":"10.1016\/j.ijrobp.2025.05.062_bib0002","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/j.critrevonc.2014.06.004","article-title":"Lymphedema following breast cancer treatment and impact on quality of life: A review","volume":"92","author":"Taghian","year":"2014","journal-title":"Crit Rev Oncol Hematol"},{"key":"10.1016\/j.ijrobp.2025.05.062_bib0003","doi-asserted-by":"crossref","first-page":"5213","DOI":"10.1200\/JCO.2008.16.3725","article-title":"Prevalence of lymphedema in women with breast cancer 5 years after sentinel lymph node biopsy or axillary dissection: Objective measurements","volume":"26","author":"McLaughlin","year":"2008","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.ijrobp.2025.05.062_bib0004","doi-asserted-by":"crossref","first-page":"5220","DOI":"10.1200\/JCO.2008.16.3766","article-title":"Prevalence of lymphedema in women with breast cancer 5 years after sentinel lymph node biopsy or axillary dissection: Patient perceptions and precautionary behaviors","volume":"26","author":"McLaughlin","year":"2008","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.ijrobp.2025.05.062_bib0005","doi-asserted-by":"crossref","first-page":"2926","DOI":"10.1245\/s10434-010-1112-2","article-title":"Tissue expander breast reconstruction is not associated with an increased risk of lymphedema","volume":"17","author":"Avraham","year":"2010","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.ijrobp.2025.05.062_bib0006","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1007\/s10549-021-06507-x","article-title":"Validation of a nomogram for predicting the risk of lymphedema following contemporary treatment for breast cancer: A large multi-institutional study (KROG 20-05)","volume":"192","author":"Byun","year":"2022","journal-title":"Breast Cancer Res Treat"},{"key":"10.1016\/j.ijrobp.2025.05.062_bib0007","doi-asserted-by":"crossref","first-page":"3536","DOI":"10.1200\/JCO.2007.14.4899","article-title":"Lymphedema after breast cancer: Incidence, risk factors, and effect on upper body function","volume":"26","author":"Hayes","year":"2008","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.ijrobp.2025.05.062_bib0008","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1002\/jso.23365","article-title":"Trends in post-mastectomy reconstruction: A SEER database analysis","volume":"108","author":"Lang","year":"2013","journal-title":"J Surg Oncol"},{"key":"10.1016\/j.ijrobp.2025.05.062_bib0009","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1097\/PRS.0b013e3181c49477","article-title":"Breast reconstruction and lymphedema","volume":"125","author":"Chang","year":"2010","journal-title":"Plast Reconstr Surg"},{"key":"10.1016\/j.ijrobp.2025.05.062_bib0010","doi-asserted-by":"crossref","first-page":"1169","DOI":"10.1097\/PRS.0b013e31826d0faa","article-title":"Reduced incidence of breast cancer\u2013related lymphedema following mastectomy and breast reconstruction versus mastectomy alone","volume":"130","author":"Card","year":"2012","journal-title":"Plast Reconstr Surg"},{"key":"10.1016\/j.ijrobp.2025.05.062_bib0011","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/j.breast.2012.04.009","article-title":"The impact of immediate breast reconstruction on post-mastectomy lymphedema in patients undergoing modified radical mastectomy","volume":"22","author":"Lee","year":"2013","journal-title":"Breast"},{"key":"10.1016\/j.ijrobp.2025.05.062_bib0012","doi-asserted-by":"crossref","first-page":"214e","DOI":"10.1097\/PRS.0000000000009831","article-title":"Association between immediate breast reconstruction and the development of breast cancer\u2013related lymphedema","volume":"151","author":"Jeon","year":"2023","journal-title":"Plast Reconstr Surg"},{"key":"10.1016\/j.ijrobp.2025.05.062_bib0013","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1097\/SLA.0000000000001128","article-title":"Immediate implant reconstruction is associated with a reduced risk of lymphedema compared to mastectomy alone: A prospective cohort study","volume":"263","author":"Miller","year":"2016","journal-title":"Ann Surg"},{"key":"10.1016\/j.ijrobp.2025.05.062_bib0014","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1016\/j.bjps.2018.01.012","article-title":"Breast reconstruction and risk of arm lymphedema development: A meta-analysis","volume":"71","author":"Siotos","year":"2018","journal-title":"J Plast Reconstr Aesthet Surg"},{"key":"10.1016\/j.ijrobp.2025.05.062_bib0015","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1089\/lrb.2017.0047","article-title":"Diagnostic accuracy of clinical measures considering segmental tissue composition and volume changes of breast cancer-related lymphedema","volume":"16","author":"Yang","year":"2018","journal-title":"Lymphat Res Biol"},{"key":"10.1016\/j.ijrobp.2025.05.062_bib0016","first-page":"3","article-title":"The diagnosis and treatment of peripheral lymphedema: 2020 Consensus Document of the International Society of Lymphology","volume":"53","year":"2020","journal-title":"Lymphology"},{"key":"10.1016\/j.ijrobp.2025.05.062_bib0017","doi-asserted-by":"crossref","first-page":"1959","DOI":"10.1245\/s10434-009-0452-2","article-title":"The risk of developing arm lymphedema among breast cancer survivors: A meta-analysis of treatment factors","volume":"16","author":"Tsai","year":"2009","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.ijrobp.2025.05.062_bib0018","doi-asserted-by":"crossref","first-page":"379","DOI":"10.21037\/gs.2017.11.04","article-title":"Breast cancer-related lymphedema: Risk factors, precautionary measures, and treatments","volume":"7","author":"Gillespie","year":"2018","journal-title":"Gland Surg"},{"key":"10.1016\/j.ijrobp.2025.05.062_bib0019","doi-asserted-by":"crossref","first-page":"3408","DOI":"10.1002\/cncr.34377","article-title":"Risk factors for breast cancer\u2013related lymphedema in patients undergoing 3 years of prospective surveillance with intervention","volume":"128","author":"Koelmeyer","year":"2022","journal-title":"Cancer"},{"key":"10.1016\/j.ijrobp.2025.05.062_bib0020","doi-asserted-by":"crossref","first-page":"1303","DOI":"10.1016\/S1470-2045(14)70460-7","article-title":"Radiotherapy or surgery of the axilla after a positive sentinel node in breast cancer (EORTC 10981-22023 AMAROS): A randomised, multicentre, open-label, phase 3 non-inferiority trial","volume":"15","author":"Donker","year":"2014","journal-title":"Lancet Oncol"},{"key":"10.1016\/j.ijrobp.2025.05.062_bib0021","doi-asserted-by":"crossref","first-page":"2159","DOI":"10.1200\/JCO.22.01565","article-title":"Radiotherapy or surgery of the axilla after a positive sentinel node in breast cancer: 10-year results of the randomized controlled EORTC 10981-22023 AMAROS trial","volume":"41","author":"Bartels","year":"2023","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.ijrobp.2025.05.062_bib0022","doi-asserted-by":"crossref","first-page":"907","DOI":"10.1016\/j.ijrobp.2011.05.043","article-title":"Breast cancer-related arm lymphedema: Incidence rates, diagnostic techniques, optimal management and risk reduction strategies","volume":"81","author":"Shah","year":"2011","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2025.05.062_bib0023","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1007\/s10549-016-4089-0","article-title":"Radiation therapy targets and the risk of breast cancer-related lymphedema: A systematic review and network meta-analysis","volume":"162","author":"Shaitelman","year":"2017","journal-title":"Breast Cancer Res Treat"},{"key":"10.1016\/j.ijrobp.2025.05.062_bib0024","doi-asserted-by":"crossref","first-page":"349","DOI":"10.4048\/jbc.2022.25.e37","article-title":"Intensity modulated radiotherapy and volumetric modulated arc therapy in the treatment of breast cancer: An updated review","volume":"25","author":"Chang","year":"2022","journal-title":"J Breast Cancer"},{"key":"10.1016\/j.ijrobp.2025.05.062_bib0025","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1002\/ijc.33525","article-title":"Hypofractionated volumetric-modulated arc therapy for breast cancer: A propensity-score-weighted comparison of radiation-related toxicity","volume":"149","author":"Kim","year":"2021","journal-title":"Int J Cancer"},{"key":"10.1016\/j.ijrobp.2025.05.062_bib0026","doi-asserted-by":"crossref","first-page":"2734","DOI":"10.1158\/1055-9965.EPI-09-1245","article-title":"Risk factors for lymphedema after breast cancer treatment","volume":"19","author":"Norman","year":"2010","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"10.1016\/j.ijrobp.2025.05.062_bib0027","doi-asserted-by":"crossref","first-page":"3518","DOI":"10.1097\/JS9.0000000000001278","article-title":"Incidence and risk factors of breast cancer-related lymphedema in Korea: A nationwide retrospective cohort study","volume":"110","author":"Ahn","year":"2024","journal-title":"Int J Surg"},{"key":"10.1016\/j.ijrobp.2025.05.062_bib0028","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1007\/s10549-013-2715-7","article-title":"Impact of body mass index and weight fluctuation on lymphedema risk in patients treated for breast cancer","volume":"142","author":"Jammallo","year":"2013","journal-title":"Breast Cancer Res Treat"},{"key":"10.1016\/j.ijrobp.2025.05.062_bib0029","doi-asserted-by":"crossref","DOI":"10.1016\/j.suronc.2024.102124","article-title":"Breast cancer-related lymphedema: A critical review on recent progress","volume":"56","author":"Sharifi","year":"2024","journal-title":"Surg Oncol"},{"key":"10.1016\/j.ijrobp.2025.05.062_bib0030","doi-asserted-by":"crossref","first-page":"1430","DOI":"10.1093\/annonc\/mdn153","article-title":"Satisfaction with and psychological impact of immediate and deferred breast reconstruction","volume":"19","author":"Fern\u00e1ndez-Delgado","year":"2008","journal-title":"Ann Oncol"},{"key":"10.1016\/j.ijrobp.2025.05.062_bib0031","doi-asserted-by":"crossref","first-page":"134e","DOI":"10.1097\/PRS.0000000000001417","article-title":"A propensity-matched analysis of the influence of breast reconstruction on subsequent development of lymphedema","volume":"136","author":"Basta","year":"2015","journal-title":"Plast Reconstr Surg"},{"key":"10.1016\/j.ijrobp.2025.05.062_bib0032","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1002\/bjs.10397","article-title":"Method of breast reconstruction and the development of lymphoedema","volume":"104","author":"Lee","year":"2017","journal-title":"Br J Surg"},{"key":"10.1016\/j.ijrobp.2025.05.062_bib0033","doi-asserted-by":"crossref","first-page":"1177","DOI":"10.1016\/j.ejso.2023.01.027","article-title":"Association of the breast reconstruction modality with the development of postmastectomy lymphedema: A long-term follow-up study","volume":"49","author":"Lee","year":"2023","journal-title":"Eur J Surg Oncol"},{"key":"10.1016\/j.ijrobp.2025.05.062_bib0034","doi-asserted-by":"crossref","first-page":"1218","DOI":"10.1016\/j.bjps.2016.06.001","article-title":"Breast reconstruction and risk of lymphedema after mastectomy: A prospective cohort study with 10 years of follow-up","volume":"69","author":"Menezes","year":"2016","journal-title":"J Plast Reconstr Aesthet Surg"},{"key":"10.1016\/j.ijrobp.2025.05.062_bib0035","doi-asserted-by":"crossref","first-page":"1330","DOI":"10.4143\/crt.2015.463","article-title":"Identification of prognostic risk factors for transient and persistent lymphedema after multimodal treatment for breast cancer","volume":"48","author":"Kim","year":"2016","journal-title":"Cancer Res Treat"},{"key":"10.1016\/j.ijrobp.2025.05.062_bib0036","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1002\/cncr.33183","article-title":"A randomized study to prevent lymphedema in women treated for breast cancer: CALGB 70305 (Alliance)","volume":"127","author":"Paskett","year":"2021","journal-title":"Cancer"},{"key":"10.1016\/j.ijrobp.2025.05.062_bib0037","doi-asserted-by":"crossref","first-page":"7487","DOI":"10.1245\/s10434-024-15706-x","article-title":"Timing of breast cancer related lymphedema development over 3 years: Observations from a large, prospective randomized screening trial comparing bioimpedance spectroscopy (BIS) versus tape measure","volume":"31","author":"Shah","year":"2024","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.ijrobp.2025.05.062_bib0038","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1089\/lrb.2014.0019","article-title":"Clinical measurements of lymphedema","volume":"12","author":"Johnson","year":"2014","journal-title":"Lymphat Res Biol"},{"key":"10.1016\/j.ijrobp.2025.05.062_bib0039","doi-asserted-by":"crossref","first-page":"1521","DOI":"10.1002\/jso.27841","article-title":"Breast cancer-related lymphedema: A comprehensive analysis of risk factors","volume":"130","author":"Siotos","year":"2024","journal-title":"J Surg Oncol"}],"container-title":["International Journal of Radiation Oncology*Biology*Physics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0360301625005310?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0360301625005310?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T17:45:09Z","timestamp":1762019109000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0360301625005310"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11]]},"references-count":39,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2025,11]]}},"alternative-id":["S0360301625005310"],"URL":"https:\/\/doi.org\/10.1016\/j.ijrobp.2025.05.062","relation":{},"ISSN":["0360-3016"],"issn-type":[{"value":"0360-3016","type":"print"}],"subject":[],"published":{"date-parts":[[2025,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Relationship of Immediate Breast Reconstruction and the Development of Lymphedema in Breast Cancer Patients With Radiation Therapy","name":"articletitle","label":"Article Title"},{"value":"International Journal of Radiation Oncology*Biology*Physics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ijrobp.2025.05.062","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}