{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T21:08:55Z","timestamp":1789160935920,"version":"build-2803163510"},"reference-count":25,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100010476","name":"Tata Memorial Centre","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100010476","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","redjournal.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Journal of Radiation Oncology*Biology*Physics"],"published-print":{"date-parts":[[2026,7]]},"DOI":"10.1016\/j.ijrobp.2026.07.018","type":"journal-article","created":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T23:04:28Z","timestamp":1785539068000},"update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Empty-RT: A Phase 2 Trial of Prostate Stereotactic Body Radiation Therapy With an Empty Bladder Approach"],"prefix":"10.1016","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6011-9319","authenticated-orcid":false,"given":"Vedang","family":"Murthy","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simran","family":"Gulati","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suman","family":"Ghosh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shivani","family":"Sable","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Reena","family":"Phurailatpam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Divya","family":"Patil","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ritesh","family":"Mhatre","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nazneen","family":"Chougle","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mihir","family":"Solanki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maneesh","family":"Singh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Parth","family":"Verma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pallavi","family":"Singh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Priyamvada","family":"Maitre","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ijrobp.2026.07.018_bib0001","doi-asserted-by":"crossref","first-page":"1413","DOI":"10.1056\/NEJMoa2403365","article-title":"Phase 3 trial of stereotactic body radiotherapy in localized prostate cancer","volume":"391","author":"van As","year":"2024","journal-title":"N Engl J Med."},{"key":"10.1016\/j.ijrobp.2026.07.018_bib0002","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1120\/jacmp.v8i1.2286","article-title":"Effect of bladder filling on doses to prostate and organs at risk: A treatment planning study","volume":"8","author":"Moiseenko","year":"2006","journal-title":"J Appl Clin Med Phys."},{"key":"10.1016\/j.ijrobp.2026.07.018_bib0003","doi-asserted-by":"crossref","first-page":"813","DOI":"10.1259\/bjr\/50048151","article-title":"Assessing the daily consistency of bladder filling using an ultrasonic Bladderscan device in men receiving radical conformal radiotherapy for prostate cancer","volume":"84","author":"Hynds","year":"2011","journal-title":"Br J Radiol."},{"key":"10.1016\/j.ijrobp.2026.07.018_bib0004","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1016\/j.ijrobp.2005.12.039","article-title":"Bladder filling variation during radiation treatment of prostate cancer: Can the use of a bladder ultrasound scanner and biofeedback optimize bladder filling?","volume":"65","author":"Stam","year":"2006","journal-title":"Int J Radiat Oncol Biol Phys."},{"key":"10.1016\/j.ijrobp.2026.07.018_bib0005","doi-asserted-by":"crossref","DOI":"10.3389\/fonc.2023.1200270","article-title":"Assessment of bladder filling during prostate cancer radiation therapy with ultrasound and cone-beam CT","volume":"13","author":"Chauhan","year":"2023","journal-title":"Front Oncol."},{"issue":"6 suppl 2","key":"10.1016\/j.ijrobp.2026.07.018_bib0006","doi-asserted-by":"crossref","first-page":"S226","DOI":"10.1016\/j.bj.2020.11.004","article-title":"Bladder volume reproducibility after water consumption in patients with prostate cancer undergoing radiotherapy: A systematic review and meta-analysis","volume":"44","author":"Chen","year":"2021","journal-title":"Biomed J."},{"key":"10.1016\/j.ijrobp.2026.07.018_bib0007","doi-asserted-by":"crossref","first-page":"e203","DOI":"10.1016\/j.prro.2013.11.006","article-title":"A randomized trial comparing bladder volume consistency during fractionated prostate radiation therapy","volume":"4","author":"Mullaney","year":"2014","journal-title":"Pract Radiat Oncol."},{"key":"10.1016\/j.ijrobp.2026.07.018_bib0008","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1186\/s13014-020-01681-6","article-title":"Strict bladder filling and rectal emptying during prostate SBRT: Does it make a dosimetric or clinical difference?","volume":"15","author":"Byun","year":"2020","journal-title":"Radiat Oncol."},{"key":"10.1016\/j.ijrobp.2026.07.018_bib0009","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1007\/s00066-010-2105-6","article-title":"Variability in bladder volumes of full bladders in definitive radiotherapy for cases of localized prostate cancer","volume":"186","author":"Nakamura","year":"2010","journal-title":"Strahlenther Onkol."},{"key":"10.1016\/j.ijrobp.2026.07.018_bib0010","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1016\/j.radonc.2006.05.007","article-title":"Variability of bladder filling in patients receiving radical radiotherapy to the prostate","volume":"79","author":"O\u2019Doherty","year":"2006","journal-title":"Radiother Oncol."},{"key":"10.1016\/j.ijrobp.2026.07.018_bib0011","doi-asserted-by":"crossref","first-page":"1109","DOI":"10.1016\/0360-3016(95)00253-7","article-title":"Variation in volumes, dose-volume histograms, and estimated normal tissue complication probabilities of rectum and bladder during conformal radiotherapy of T3 prostate cancer","volume":"33","author":"Lebesque","year":"1995","journal-title":"Int J Radiat Oncol Biol Phys."},{"key":"10.1016\/j.ijrobp.2026.07.018_bib0012","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/j.tipsro.2017.10.001","article-title":"The impact of bladder preparation protocols on post treatment toxicity in radiotherapy for localised prostate cancer patients","volume":"3-4","author":"Tsang","year":"2017","journal-title":"Tech Innov Patient Support Radiat Oncol."},{"key":"10.1016\/j.ijrobp.2026.07.018_bib0013","doi-asserted-by":"crossref","DOI":"10.1259\/bjr.20200548","article-title":"The implementation of an empty bladder filling protocol for localised prostate volumetric modulated arctherapy (VMAT): Early results of a single institution service evaluation","volume":"93","author":"Chetiyawardana","year":"2020","journal-title":"Br J Radiol."},{"key":"10.1016\/j.ijrobp.2026.07.018_bib0014","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.radonc.2018.01.014","article-title":"ESTRO ACROP consensus guideline on CT- and MRI-based target volume delineation for primary radiation therapy of localized prostate cancer","volume":"127","author":"Salembier","year":"2018","journal-title":"Radiother Oncol."},{"key":"10.1016\/j.ijrobp.2026.07.018_bib0015","doi-asserted-by":"crossref","first-page":"1234","DOI":"10.1200\/JCO.20.03282","article-title":"Prostate-only versus whole-pelvic radiation therapy in high-risk and very high-risk prostate cancer (POP-RT): Outcomes from phase III randomized controlled trial","volume":"39","author":"Murthy","year":"2021","journal-title":"J Clin Oncol."},{"key":"10.1016\/j.ijrobp.2026.07.018_bib0016","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1016\/j.ijrobp.2020.08.034","article-title":"NRG oncology updated international consensus Atlas on pelvic lymph node volumes for intact and postoperative prostate cancer","volume":"109","author":"Hall","year":"2021","journal-title":"Int J Radiat Oncol Biol Phys."},{"key":"10.1016\/j.ijrobp.2026.07.018_bib0017","doi-asserted-by":"crossref","first-page":"668","DOI":"10.1016\/j.adro.2019.07.007","article-title":"A phase I\/II trial of fairly brief androgen suppression and stereotactic radiation therapy for high-risk prostate cancer (FASTR-2): Preliminary results and toxicity analysis","volume":"4","author":"Callan","year":"2019","journal-title":"Adv Radiat Oncol."},{"key":"10.1016\/j.ijrobp.2026.07.018_bib0018","doi-asserted-by":"crossref","first-page":"e39","DOI":"10.1016\/j.clon.2019.09.046","article-title":"A phase I\/II study of stereotactic hypofractionated once-weekly radiation therapy (SHORT) for prostate cancer","volume":"32","author":"Mallick","year":"2020","journal-title":"Clin Oncol (R Coll Radiol)."},{"key":"10.1016\/j.ijrobp.2026.07.018_bib0019","doi-asserted-by":"crossref","unstructured":"Murthy V, Maitre P, Arunsingh M, et al. OC-0924 Prostate RT In high risk or N+ Moderate vs Extreme hypofractionation (PRIME): An Interim analysis. Radiother Oncol. 2023;182:S770\u2013S771. DOI:10.1016\/S0167-8140(23)08750-9 URL https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0167814023087509","DOI":"10.1016\/S0167-8140(23)08750-9"},{"key":"10.1016\/j.ijrobp.2026.07.018_bib0020","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.tipsro.2021.01.002","article-title":"Maintaining consistent bladder filling during external beam radiotherapy for prostate cancer","volume":"17","author":"Nasser","year":"2021","journal-title":"Tech Innov Patient Support Radiat Oncol."},{"key":"10.1016\/j.ijrobp.2026.07.018_bib0021","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1002\/j.2051-3909.2012.tb00167.x","article-title":"Measured bladder volume for radiotherapy of the prostate using the hand-held BladderScan\u00ae BVI 3000","volume":"59","author":"Gawthrop","year":"2012","journal-title":"Radiographer"},{"key":"10.1016\/j.ijrobp.2026.07.018_bib0022","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/S0167-8140(99)00011-0","article-title":"Quantification and predictors of prostate position variability in 50 patients evaluated with multiple CT scans during conformal radiotherapy","volume":"50","author":"Zelefsky","year":"1999","journal-title":"Radiother Oncol."},{"key":"10.1016\/j.ijrobp.2026.07.018_bib0023","doi-asserted-by":"crossref","first-page":"856","DOI":"10.1016\/j.ijrobp.2005.08.016","article-title":"Prostate position variability and dose-volume histograms in radiotherapy for prostate cancer with full and empty bladder","volume":"64","author":"Pinkawa","year":"2006","journal-title":"Int J Radiat Oncol Biol Phys."},{"key":"10.1016\/j.ijrobp.2026.07.018_bib0024","doi-asserted-by":"crossref","first-page":"1531","DOI":"10.1016\/S1470-2045(19)30569-8","article-title":"Intensity-modulated fractionated radiotherapy versus stereotactic body radiotherapy for prostate cancer (PACE-B): Acute toxicity findings from an international, randomised, open-label, phase 3, non-inferiority trial","volume":"20","author":"Brand","year":"2019","journal-title":"Lancet Oncol."},{"key":"10.1016\/j.ijrobp.2026.07.018_bib0025","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.radonc.2020.04.039","article-title":"Accelerating prostate stereotactic ablative body radiotherapy: Efficacy and toxicity of a randomized phase II study of 11 versus 29 days overall treatment time (PATRIOT)","volume":"149","author":"Alayed","year":"2020","journal-title":"Radiother Oncol."}],"container-title":["International Journal of Radiation Oncology*Biology*Physics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0360301626040642?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0360301626040642?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T20:44:41Z","timestamp":1789159481000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0360301626040642"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7]]},"references-count":25,"alternative-id":["S0360301626040642"],"URL":"https:\/\/doi.org\/10.1016\/j.ijrobp.2026.07.018","relation":{},"ISSN":["0360-3016"],"issn-type":[{"value":"0360-3016","type":"print"}],"subject":[],"published":{"date-parts":[[2026,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Empty-RT: A Phase 2 Trial of Prostate Stereotactic Body Radiation Therapy With an Empty Bladder Approach","name":"articletitle","label":"Article Title"},{"value":"International Journal of Radiation Oncology*Biology*Physics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ijrobp.2026.07.018","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}