{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T16:30:21Z","timestamp":1786120221277,"version":"build-2736575974"},"reference-count":18,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","license":[{"start":{"date-parts":[[2013,1,1]],"date-time":"2013-01-01T00:00:00Z","timestamp":1356998400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,7,16]],"date-time":"2013-07-16T00:00:00Z","timestamp":1373932800000},"content-version":"vor","delay-in-days":196,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/3.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2013,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>INTRODUCTION:<\/jats:title>\n                    <jats:p>Isolated superior mesentericveinous thrmbophlebitis is a rarely recognised condition associated with a high morbidity. It usually develops secondary to infection in the drainage area of the portal venous system, like appendix.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>PRESENTATION OF CASE:<\/jats:title>\n                    <jats:p>We report a case of neglected perforated acute appendicitis complicated by superior mesenteric venous pyelephlebitis patiant represented with a vague pain to right of umlicus, which is atypical this why cat scan was done and showed obstructed superiormesentric vein, portal vein was free with acute appendicitis. Appendicectomy and treatment with broad-spectrum antibiotics, anticoagulation, and platelets led to a full recovery. Follow-up imaging after one month revealed complete canalization of superior mesentric vein.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>DISCUSSION:<\/jats:title>\n                    <jats:p>Abdominal pain if atypical like our case report need imaging diagnosis. Modern diagnostic imaging techniques help the early diagnosis of acute phase pylephlebitis. CT can detect primary source of infection, extent of pylephlebitis, CT scan is the most reliable initially. Ultrasound scan with color flow Doppler is also a sensitive test for confirming partial patency of the portal vein and portal vein thrombosis accidentally discovered complete obliteration of superior mesenteric vein with thrombosis which remained not propagated by serial Doppler ultrasound of liver.<\/jats:p>\n                    <jats:p>Appropriate treatment should be initiated as soon as possible. To avoid extension to portal vein. The principal treatment for pylephlebitis is to remove the source of infection as appendicectomy.<\/jats:p>\n                    <jats:p>Anticoagulants must be used. Regarding the treatment of portal thrombosis, post operative use of heparin has been advocated.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSION:<\/jats:title>\n                    <jats:p>Cat scan play an important role in case of atypical abdominal pain.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1016\/j.ijscr.2011.10.019","type":"journal-article","created":{"date-parts":[[2011,12,7]],"date-time":"2011-12-07T08:19:53Z","timestamp":1323245993000},"page":"432-434","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":13,"title":["Isolated superior mesenteric venous thrombophlebitis with acute appendicitis"],"prefix":"10.1097","volume":"4","author":[{"given":"Mohsen Mohamed","family":"Karam","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohaed Fahmy","family":"Abdalla","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Said","family":"Bedair","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-24-20260114","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1093\/clinids\/21.5.1114","article-title":"Septic thrombophlebitis of the portal vein (pylephlebitis): diagnosis and management in the modern era","volume":"21","author":"Plemmons","year":"1995","journal-title":"Clin Infect Dis"},{"key":"R2-24-20260114","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1016\/0016-5085(82)90028-2","article-title":"Mesenteric vein thrombosis","volume":"82","author":"Grendell","year":"1982","journal-title":"Gastroenterology"},{"key":"R3-24-20260114","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1097\/00000658-189521060-00002","article-title":"The operative relief of gangrene of the intestine due to occlusion of the mesenteric vessels","volume":"21","author":"Eliot","year":"1895","journal-title":"Ann Surg"},{"key":"R4-24-20260114","first-page":"65","article-title":"Pyelephlebitis","volume":"106","author":"Klinefelter","year":"1960","journal-title":"Bull Johns Hopkins Hosp"},{"key":"R5-24-20260114","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1148\/radiology.171.3.2655006","article-title":"Complicated appendiceal inflammatory disease in children pylephlebitis and liver abscess","volume":"171","author":"Slovis","year":"1989","journal-title":"Radiology"},{"key":"R7-24-20260114","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1001\/archpedi.1994.02170080083016","article-title":"Escherichia coli septicemia in nonperforated appendicitis","volume":"148","author":"Ruff","year":"1994","journal-title":"Arch Pediatr Adolesc Med"},{"key":"R10-24-20260114","first-page":"1099","article-title":"Radiological case of the month. Pylephlebitis secondary to unsuspected appendiceal rupture","volume":"143","author":"Giuliano","year":"1989","journal-title":"Am J Dis Child"},{"key":"R11-24-20260114","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1016\/S0002-9610(96)00220-6","article-title":"The role of anticoagulation in pylephlebitis","volume":"172","author":"Baril","year":"1996","journal-title":"Am J Surg"},{"key":"R12-24-20260114","doi-asserted-by":"crossref","first-page":"73","DOI":"10.3904\/kjim.1999.14.1.73","article-title":"Pylephlebitis associated with appendicitis","volume":"14","author":"Lim","year":"1999","journal-title":"Korean J Intern Med"},{"key":"R13-24-20260114","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1097\/00004728-200009000-00017","article-title":"Septic thrombophlebitis of the mesenteric and portal veins: CT imaging","volume":"24","author":"Balthazar","year":"2000","journal-title":"J Comput Assist Tomogr"},{"key":"R14-24-20260114","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1007\/s00595-003-2654-8","article-title":"Septic thrombophlebitis of the portal and superior mesenteric veins as a complication of appendicitis: report of a case","volume":"34","author":"Nishimori","year":"2004","journal-title":"Surg Today"},{"key":"R15-24-20260114","doi-asserted-by":"crossref","first-page":"1574","DOI":"10.1053\/jpsu.2001.27052","article-title":"Pylephlebitis after appendicitis in a child","volume":"36","author":"Vanamo","year":"2001","journal-title":"J Pediatric Surg"},{"key":"R16-24-20260114","first-page":"108","article-title":"Interval laparoscopic appendectomy for appendicitis complicated by pylephlebitis","volume":"10","author":"Stitzenberg","year":"2006","journal-title":"JSLS"},{"key":"R17-24-20260114","doi-asserted-by":"crossref","first-page":"1116","DOI":"10.1001\/archsurg.1987.01400220026003","article-title":"Pylethrombosis: serendipitous radiologic diagnosis","volume":"122","author":"Harch","year":"1987","journal-title":"Arch Surg"},{"key":"R18-24-20260114","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1016\/S0002-9610(96)00220-6","article-title":"The role of anticoagulation in pylephlebitis","volume":"172","author":"Baril","year":"1996","journal-title":"Am J Surg"},{"key":"R19-24-20260114","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1016\/0002-9610(54)90358-X","article-title":"Pylephlebitis and liver abscess","volume":"88","author":"Hoffman","year":"1954","journal-title":"Am J Surg"},{"key":"R20-24-20260114","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1177\/000313480407000707","article-title":"Treatment of superior mesenteric and portal vein thrombosis with direct thrombolytic infusion via operatively placed mesenteric catheter","volume":"70","author":"Kaplan","year":"2004","journal-title":"Am Surg"},{"key":"R21-24-20260114","first-page":"584","article-title":"Ruptured retrocecal appendicitis in an adolescent presenting as portal-mesenteric thrombosis and pylephlebitis","volume":"27","author":"Kader","year":"1998","journal-title":"J Ped Gastroenterol Nutr"}],"container-title":["International Journal of Surgery Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2210261211001398?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2210261211001398?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ovid.com\/01612930-201304040-00024","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T20:28:05Z","timestamp":1786048085000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/01612930-201304040-00024"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,1]]},"references-count":18,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2013]]}},"URL":"https:\/\/doi.org\/10.1016\/j.ijscr.2011.10.019","relation":{},"ISSN":["2210-2612"],"issn-type":[{"value":"2210-2612","type":"print"}],"subject":[],"published":{"date-parts":[[2013,1]]}}}