{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,27]],"date-time":"2026-06-27T23:09:20Z","timestamp":1782601760348,"version":"3.54.5"},"reference-count":14,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"7","license":[{"start":{"date-parts":[[2012,1,1]],"date-time":"2012-01-01T00:00:00Z","timestamp":1325376000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,7,16]],"date-time":"2013-07-16T00:00:00Z","timestamp":1373932800000},"content-version":"vor","delay-in-days":562,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/3.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2012,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>INTRODUCTION:<\/jats:title>\n                    <jats:p>Skeletal muscle metastases from carcinomas, especially to intercostal muscles, are rare. Most metastatic chest wall tumors from hepatocellular carcinoma (HCC) result from disseminations through needle tracts of intrahepatic HCC treatments.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>PRESENTATION OF CASE:<\/jats:title>\n                    <jats:p>We report the case of a 65-year-old man with chronic viral hepatitis B whose intrahepatic lesions were stabilized by repeated radiofrequency ablations and transcatheter arterial chemoembolization. Follow-up computed tomography demonstrated a well-enhanced mass in the right chest wall. Because \u03b1-fetoprotein and des-\u03b3-carboxy prothrombin levels were elevated and no other tumors were detected, we diagnosed the mass as an extrahepatic metastasis from the HCC and resected it along with the surrounding ribs. There was no involvement of the bone, pleura, and lung.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>DISCUSSION:<\/jats:title>\n                    <jats:p>The tumor was microscopically diagnosed as an intercostal muscle tumor metastasized from HCC, which has not been documented previously. The resection rate of extrahepatic tumors of HCC is low in literature. No other apparent extrahepatic recurrence has been observed for more than 20 months after the surgery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSION:<\/jats:title>\n                    <jats:p>We report the case of HCC patient who underwent surgical resection of an intercostal muscle tumor that had metastasized from HCC. Pathological examination of the tumor revealed the tumor cells in the blood vessels, and we speculate it hematogeneous metastasis.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1016\/j.ijscr.2012.04.003","type":"journal-article","created":{"date-parts":[[2012,4,9]],"date-time":"2012-04-09T19:55:00Z","timestamp":1334001300000},"page":"322-326","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":13,"title":["Solitary metastasis to the intercostal muscle from hepatocellular carcinoma"],"prefix":"10.1097","volume":"3","author":[{"given":"Katsuyoshi","family":"Furumoto","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Koki","family":"Miura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daisuke","family":"Nagashima","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hidenobu","family":"Kojima","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomohiko","family":"Mori","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daisuke","family":"Ito","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kozo","family":"Kajimura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masafumi","family":"Kogire","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-28-20260114","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1016\/j.amjmed.2003.07.003","article-title":"An anterior chest wall mass","volume":"115","author":"Simpson","year":"2003","journal-title":"American Journal of Medicine"},{"key":"R2-28-20260114","doi-asserted-by":"crossref","first-page":"698","DOI":"10.1148\/radiology.216.3.r00se24698","article-title":"Extrahepatic metastases of hepatocellular carcinoma","volume":"216","author":"Katyal","year":"2000","journal-title":"Radiology"},{"key":"R3-28-20260114","doi-asserted-by":"crossref","first-page":"414","DOI":"10.3748\/wjg.v13.i3.414","article-title":"Clinical features and prognosis of patients with extrahepatic metastases from hepatocellular carcinoma","volume":"13","author":"Uka","year":"2007","journal-title":"World Journal of Gastroenterology"},{"key":"R4-28-20260114","doi-asserted-by":"crossref","first-page":"1781","DOI":"10.1111\/j.1440-1746.2005.03919.x","article-title":"Clinical features of hepatocellular carcinoma with extrahepatic metastases","volume":"20","author":"Natsuizaka","year":"2005","journal-title":"Journal of Gastroenterology and Hepatology"},{"key":"R5-28-20260114","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1016\/j.surg.2006.06.033","article-title":"Patterns and clinicopathologic features of extrahepatic recurrence of hepatocellular carcinoma after curative resection","volume":"141","author":"Yang","year":"2007","journal-title":"Surgery"},{"key":"R6-28-20260114","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1097\/01.meg.0000059105.41030.55","article-title":"A solitary chest wall metastasis from unknown primary hepatocellular carcinoma","volume":"15","author":"Hofmann","year":"2003","journal-title":"European Journal of Gastroenterology and Hepatology"},{"key":"R7-28-20260114","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1186\/1471-2407-4-89","article-title":"Atypical presentation of hepatocellular carcinoma: a mass on the left thoracic wall","volume":"4","author":"Coban","year":"2004","journal-title":"BMC Cancer"},{"key":"R8-28-20260114","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1186\/1471-2407-6-169","article-title":"Recurrence in skeletal muscle from squamous cell carcinoma of the uterine cervix: a case report and review of the literature","volume":"6","author":"Ferrandina","year":"2006","journal-title":"BMC Cancer"},{"key":"R9-28-20260114","doi-asserted-by":"crossref","first-page":"4270","DOI":"10.3748\/wjg.v13.i31.4270","article-title":"Ectopic hepatocellular carcinoma arising from pancreas: a case report and review of the literature","volume":"13","author":"Kubota","year":"2007","journal-title":"World Journal of Gastroenterology"},{"key":"R10-28-20260114","first-page":"57","article-title":"Metastasis of malignant neoplasms to skeletal muscle","volume":"31","author":"Acinas Garcia","year":"1984","journal-title":"Revista Espanola de Oncologia"},{"key":"R11-28-20260114","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1038\/sj.neo.7900138","article-title":"Resistance of muscle to tumor metastases: a role for a3 adenosine receptor agonists","volume":"3","author":"Bar-Yehuda","year":"2001","journal-title":"Neoplasia"},{"key":"R12-28-20260114","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1056\/NEJM199003013220907","article-title":"The cellular basis of site-specific tumor metastasis","volume":"322","author":"Zetter","year":"1990","journal-title":"New England Journal of Medicine"},{"key":"R13-28-20260114","doi-asserted-by":"crossref","first-page":"75","DOI":"10.3109\/2000-1967-183","article-title":"Skeletal muscle metastasis secondary to cancer \u2013 a report of seven cases","volume":"110","author":"Koike","year":"2005","journal-title":"Upsala Journal of Medical Sciences"},{"key":"R14-28-20260114","doi-asserted-by":"crossref","first-page":"5481","DOI":"10.3748\/wjg.15.5481","article-title":"Efficacy of surgical resection in management of isolated extrahepatic metastases of hepatocellular carcinoma","volume":"15","author":"Chan","year":"2009","journal-title":"World Journal of Gastroenterology"}],"container-title":["International Journal of Surgery Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2210261212000703?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2210261212000703?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.lww.com\/01612930-201203070-00028","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,14]],"date-time":"2026-01-14T13:02:31Z","timestamp":1768395751000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/01612930-201203070-00028"}},"subtitle":["A case report"],"short-title":[],"issued":{"date-parts":[[2012,1]]},"references-count":14,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2012]]}},"URL":"https:\/\/doi.org\/10.1016\/j.ijscr.2012.04.003","relation":{},"ISSN":["2210-2612"],"issn-type":[{"value":"2210-2612","type":"print"}],"subject":[],"published":{"date-parts":[[2012,1]]}}}