{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,19]],"date-time":"2026-01-19T04:29:32Z","timestamp":1768796972371,"version":"3.49.0"},"reference-count":16,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"7","license":[{"start":{"date-parts":[[2012,1,1]],"date-time":"2012-01-01T00:00:00Z","timestamp":1325376000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,7,16]],"date-time":"2013-07-16T00:00:00Z","timestamp":1373932800000},"content-version":"vor","delay-in-days":562,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/3.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2012,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>INTRODUCTION:<\/jats:title>\n                    <jats:p>Lymphoma is a rare complication of long-standing Crohn's disease. We report a rare case of a diffuse, B-cell non-Hodgkin's lymphoma of the mesentery in a patient receiving treatment for Crohn's disease.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>PRESENTATION OF CASE:<\/jats:title>\n                    <jats:p>A 52 year-old patient presented with abdominal pain, anorexia and postprandial fullness. Abdominal examination revealed a firm mass, extending from the epigastrium to the right iliac fossa. CT scan showed a large intra-abdominal mass with air-fluid levels within, and soft tissue density along its walls, surrounded by distended bowel loops. The patient was scheduled for surgery due to clinical assumption of an intra-abdominal abscess. At laparotomy an ill-defined, lobulated mass with cystic areas was noted rising from the mesentery. Frozen section biopsy of the cystic mass revealed a non-Hodgkin follicle center B-cell lymphoma of the mesentery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>DISCUSSION:<\/jats:title>\n                    <jats:p>To the best of our knowledge, this is an extremely rare case of lymphoma development in the mesentery, in a patient receiving treatment for Crohn's disease. Although the development of abdominal lymphomas can be justified as a possible consequence of the chronic immune-modulating therapy, their location can lead to diagnostic pitfalls.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSION:<\/jats:title>\n                    <jats:p>Although mesentery has scarcely been presented as a potential site of occurrence of abdominal lymphomas in the process of treatment of inflammatory bowel diseases, this rare entity should be considered in the differential diagnosis of intra-abdominal lymphomas in patients with inflammatory bowel disease. In cases where imaging techniques do not provide definitive answers, surgical intervention can safely pose the accurate diagnosis.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1016\/j.ijscr.2012.04.005","type":"journal-article","created":{"date-parts":[[2012,4,16]],"date-time":"2012-04-16T16:36:46Z","timestamp":1334594206000},"page":"343-345","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":3,"title":["Mesentery lymphoma in a patient with Crohn's disease"],"prefix":"10.1097","volume":"3","author":[{"given":"Nikolaos","family":"Koronakis","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emmanouil","family":"Lagoudianakis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dimitrios","family":"Keramidaris","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Apostolos","family":"Pappas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"George","family":"Gemenetzis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Charalampos","family":"Seretis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John","family":"Chrysikos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andreas","family":"Manouras","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"R1-34-20260114","doi-asserted-by":"crossref","first-page":"2914","DOI":"10.1002\/1097-0142(19851215)56:12<2914::AID-CNCR2820561232>3.0.CO;2-J","article-title":"Extraintestinal cancers in inflammatory bowel disease","volume":"56","author":"Greenstein","year":"1985","journal-title":"Cancer"},{"key":"R2-34-20260114","doi-asserted-by":"crossref","first-page":"574","DOI":"10.1136\/gut.2004.055111","article-title":"Clinical epidemiology\u2014how important now?","volume":"54","author":"Binder","year":"2005","journal-title":"Gut"},{"key":"R3-34-20260114","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1111\/j.1365-2796.2008.02029.x","article-title":"Autoimmune and inflammatory disorders and risk of malignant lymphomas\u2014an update","volume":"264","author":"Smedby","year":"2008","journal-title":"Journal of Internal Medicine"},{"key":"R4-34-20260114","doi-asserted-by":"crossref","first-page":"4029","DOI":"10.1182\/blood-2007-10-119974","article-title":"Autoimmune disorders and risk of non-Hodgkin lymphoma subtypes: a pooled analysis within the InterLymph Consortium","volume":"111","author":"Ekstr\u00f6m Smedby","year":"2008","journal-title":"Blood"},{"key":"R5-34-20260114","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1038\/ncprheum0620","article-title":"B-cell lymphoprolipheration in chronic inflammatory rheumatic diseases","volume":"3","author":"Hansen","year":"2007","journal-title":"Nature Clinical Practice Rheumatology"},{"key":"R6-34-20260114","doi-asserted-by":"crossref","first-page":"1101","DOI":"10.1046\/j.1365-2036.2001.01023.x","article-title":"Review article: the risk of lymphoma associated with inflammatory bowel disease and immunosuppressive treatment","volume":"15","author":"Aithal","year":"2001","journal-title":"Alimentary Pharmacology and Therapeutics"},{"key":"R7-34-20260114","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1136\/gut.2004.051771","article-title":"Risk of haematopoeitic cancer in patients with inflammatory bowel disease","volume":"54","author":"Askling","year":"2005","journal-title":"Gut"},{"key":"R8-34-20260114","doi-asserted-by":"crossref","first-page":"839","DOI":"10.1007\/s10350-006-0848-z","article-title":"The risk of cancer in patients with Crohn's disease","volume":"50","author":"Von Roon","year":"2007","journal-title":"Diseases of the Colon and Rectum"},{"key":"R9-34-20260114","doi-asserted-by":"crossref","first-page":"1299","DOI":"10.1002\/ibd.20211","article-title":"Lymphoma risk in inflammatory bowel disease: is it the disease or its treatment?","volume":"13","author":"Jones","year":"2007","journal-title":"Inflammatory Bowel Diseases"},{"key":"R10-34-20260114","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/j.critrevonc.2005.02.004","article-title":"The risk of lymphoma in the treatment of inflammatory bowel disease with immunosuppressive agents","volume":"56","author":"Kwon","year":"2005","journal-title":"Critical Reviews in Oncology\/Hematology"},{"key":"R11-34-20260114","doi-asserted-by":"crossref","first-page":"1121","DOI":"10.1136\/gut.2004.049460","article-title":"Increased risk of lymphoma among inflammatory bowel disease patients treated with azathioprine and 6-mercaptopurine","volume":"54","author":"Kandiel","year":"2005","journal-title":"Gut"},{"key":"R12-34-20260114","doi-asserted-by":"crossref","first-page":"854","DOI":"10.1002\/1097-0142(20010215)91:4<854::AID-CNCR1073>3.0.CO;2-Z","article-title":"Cancer risk in patients with inflammatory bowel disease: a population-based study","volume":"91","author":"Bernstein","year":"2001","journal-title":"Cancer"},{"key":"R13-34-20260114","first-page":"559","article-title":"An unusual case associating ileal Crohn's disease and diffuse large B-cell lymphoma of an adjacent mesenteric lymph node","volume":"122","author":"Charlotte","year":"1998","journal-title":"Archives of Pathology and Laboratory Medicine"},{"key":"R14-34-20260114","doi-asserted-by":"crossref","first-page":"1446","DOI":"10.1136\/bmj.291.6507.1446","article-title":"Imaging of abdominal abscesses","volume":"291","author":"Joseph","year":"1985","journal-title":"British Medical Journal (Clinical Research Ed"},{"key":"R15-34-20260114","first-page":"678","article-title":"Intra abdominal abscess in Crohn's disease","volume":"56","author":"Cybulsky","year":"1990","journal-title":"American Surgeon"},{"key":"R16-34-20260114","doi-asserted-by":"crossref","first-page":"628","DOI":"10.1148\/radiol.2422040431","article-title":"Case 107: lymphoma of the mesentery","volume":"242","author":"Yenarkarn","year":"2007","journal-title":"Radiology"}],"container-title":["International Journal of Surgery Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2210261212000727?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2210261212000727?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.lww.com\/01612930-201203070-00034","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,14]],"date-time":"2026-01-14T13:02:38Z","timestamp":1768395758000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/01612930-201203070-00034"}},"subtitle":["An extremely rare entity"],"short-title":[],"issued":{"date-parts":[[2012,1]]},"references-count":16,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2012]]}},"URL":"https:\/\/doi.org\/10.1016\/j.ijscr.2012.04.005","relation":{},"ISSN":["2210-2612"],"issn-type":[{"value":"2210-2612","type":"print"}],"subject":[],"published":{"date-parts":[[2012,1]]}}}