{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,3]],"date-time":"2026-03-03T08:39:14Z","timestamp":1772527154546,"version":"3.50.1"},"reference-count":18,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"10","license":[{"start":{"date-parts":[[2013,1,1]],"date-time":"2013-01-01T00:00:00Z","timestamp":1356998400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,8,2]],"date-time":"2013-08-02T00:00:00Z","timestamp":1375401600000},"content-version":"vor","delay-in-days":213,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/3.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2013,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>INTRODUCTION:<\/jats:title>\n                    <jats:p>Idiopathic thrombocytopenic purpura (ITP) is an autoimmune disease characterized by a low platelet count and normal bone marrow. Patients with ITP undergoing surgery are thought to have increased risk for postoperative complications because of their thrombocytopenia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>PRESENTATION OF CASE:<\/jats:title>\n                    <jats:p>we report the case of a 66-year-old woman with ITP who required an emergency operation for acute appendicitis associated with disseminated intravascular coagulation. Preoperative therapy consisted of platelet transfusions only, and intraoperative hemostasis was achieved. Postoperatively, high-dose intravenous immunoglobulin (IVIg) therapy led to an increased, stable, and adequate platelet count and good hemostasis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>DISCUSSION:<\/jats:title>\n                    <jats:p>The outcome of this case suggests that IVIg therapy is not always required for preoperative management of patients with.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSION:<\/jats:title>\n                    <jats:p>IVIg therapy may be useful for postoperative management after emergency surgery.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1016\/j.ijscr.2013.05.019","type":"journal-article","created":{"date-parts":[[2013,8,6]],"date-time":"2013-08-06T04:46:49Z","timestamp":1375764409000},"page":"898-900","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":6,"title":["Successful perioperative management of a patient with idiopathic thrombocytopenic purpura undergoing emergent appendectomy"],"prefix":"10.1097","volume":"4","author":[{"given":"Yoshitaka","family":"Toyomasu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rinshun","family":"Shimabukuro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hatsuo","family":"Moriyama","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daihiko","family":"Eguchi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Koichi","family":"Ishikawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fumiaki","family":"Kishihara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasurou","family":"Fukuyama","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takashi","family":"Matsumata","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erito","family":"Mochiki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroyuki","family":"Kuwano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"R1-30-20260114","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1634\/theoncologist.2008-0132","article-title":"Chronic idiopathic thrombocytopenic purpura: mechanisms of pathogenesis","volume":"14","author":"Gernsheimer","year":"2009","journal-title":"Oncologist"},{"key":"R2-30-20260114","doi-asserted-by":"crossref","first-page":"2386","DOI":"10.1182\/blood-2008-07-162503","article-title":"Standardization of terminology, definitions and outcome criteria in immune thrombocytopenic purpura of adults and children: report from an international working group","volume":"113","author":"Rodeghiero","year":"2009","journal-title":"Blood"},{"key":"R3-30-20260114","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1182\/blood.V88.1.3.3","article-title":"Idiopathic thrombocytopenic purpura: a practice guideline developed by explicit methods for the American Society of Hematology","volume":"88","author":"George","year":"1996","journal-title":"Blood"},{"key":"R5-30-20260114","doi-asserted-by":"crossref","first-page":"1228","DOI":"10.1016\/S0140-6736(81)92400-4","article-title":"Highdose intravenous gammaglobulin for idiopathic thrombocytopenic purpura in childhood","volume":"6","author":"Imbach","year":"1981","journal-title":"Lancet"},{"key":"R6-30-20260114","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1097\/00000542-197702000-00014","article-title":"Management of cesarean section in a patient with idiopathic thrombocytopenic purpura","volume":"46","author":"Angiulo","year":"1977","journal-title":"Anesthesiology"},{"key":"R7-30-20260114","doi-asserted-by":"crossref","first-page":"700","DOI":"10.3171\/jns.1976.45.6.0700","article-title":"Management of intracerebral hemorrhage in idiopathic thrombocytopenic purpura. Report of four cases","volume":"45","author":"Humphreys","year":"1976","journal-title":"Journal of Neurosurgery"},{"key":"R8-30-20260114","doi-asserted-by":"crossref","first-page":"828","DOI":"10.1007\/BF00311647","article-title":"Emergency aortic arch replacement in a patient with idiopathic thrombocytopenic purpura","volume":"26","author":"Usui","year":"1996","journal-title":"Surgery Today"},{"key":"R9-30-20260114","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/j.tmrv.2004.03.003","article-title":"Relationship between platelet count and bleeding risk in thrombocytopenic patients","volume":"18","author":"Slichter","year":"2004","journal-title":"Transfusion Medicine Reviews"},{"key":"R10-30-20260114","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1182\/blood.V70.1.177.177","article-title":"Regulation of thrombopoiesis: effects of the degree of thrombocytopenia on megakaryocyte ploidy and platelet volume","volume":"70","author":"Corash","year":"1987","journal-title":"Blood"},{"key":"R11-30-20260114","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/S0950-3536(97)80053-4","article-title":"Megakaryocytes and platelets in vascular disease","volume":"10","author":"van der Loo","year":"1997","journal-title":"Baillieres Clinical Haematology"},{"key":"R12-30-20260114","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1056\/NEJM197207272870401","article-title":"The bleeding time as a screening test for evaluation of platelet function","volume":"287","author":"Harker","year":"1972","journal-title":"New England Journal of Medicine"},{"key":"R13-30-20260114","first-page":"889","article-title":"Double lung cancer combined with idiopathic thrombocytopenic purpura. A case report","volume":"40","author":"Nonami","year":"1999","journal-title":"Journal of Cardiovascular Surgery"},{"key":"R14-30-20260114","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1160\/TH03-10-0650","article-title":"IGIV-C, a novel intravenous immunoglobulin: evaluation of safety, efficacy, mechanisms of action, and impact on quality of life","volume":"91","author":"Bussel","year":"2004","journal-title":"Thrombosis and Haemostasis"},{"key":"R16-30-20260114","first-page":"656","article-title":"Platelet transfusion. A brief review of practical aspects","volume":"11","author":"Morrison","year":"1966","journal-title":"Vox Sanguinis"},{"key":"R17-30-20260114","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1111\/j.1600-0609.1970.tb01941.x","article-title":"Survival of 51Cr-labelled autologous and isologous platelets as differential diagnostic aid in thrombocytopenic states","volume":"7","author":"Abrahamsen","year":"1970","journal-title":"Scandinavian Journal of Haematology"},{"key":"R18-30-20260114","first-page":"5","article-title":"Platelet kinetics in normal subjects and in haematological disorders; with special reference to thrombocytopenia and to the role of the spleen","volume":"5","author":"Kotilainen","year":"1969","journal-title":"Scandinavian Journal of Haematology. Supplementum"},{"key":"R19-30-20260114","doi-asserted-by":"crossref","first-page":"963","DOI":"10.1172\/JCI106077","article-title":"Thrombokinetics in man","volume":"48","author":"Harker","year":"1969","journal-title":"Journal of Clinical Investigation"},{"key":"R20-30-20260114","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/S0025-7125(16)32422-1","article-title":"Idiopathic thrombocytopenic purpura and the ITP syndrome","volume":"56","author":"Baldini","year":"1972","journal-title":"Medical Clinics of North America"}],"container-title":["International Journal of Surgery Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S221026121300237X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S221026121300237X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.lww.com\/01612930-201304100-00030","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,14]],"date-time":"2026-01-14T13:29:19Z","timestamp":1768397359000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/01612930-201304100-00030"}},"subtitle":["Report of a case"],"short-title":[],"issued":{"date-parts":[[2013,1]]},"references-count":18,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2013]]}},"URL":"https:\/\/doi.org\/10.1016\/j.ijscr.2013.05.019","relation":{},"ISSN":["2210-2612"],"issn-type":[{"value":"2210-2612","type":"print"}],"subject":[],"published":{"date-parts":[[2013,1]]}}}