{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,14]],"date-time":"2026-01-14T23:42:18Z","timestamp":1768434138465,"version":"3.49.0"},"reference-count":13,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"10","license":[{"start":{"date-parts":[[2013,1,1]],"date-time":"2013-01-01T00:00:00Z","timestamp":1356998400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,8,2]],"date-time":"2013-08-02T00:00:00Z","timestamp":1375401600000},"content-version":"vor","delay-in-days":213,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/3.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2013,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>INTRODUCTION:<\/jats:title>\n                    <jats:p>Chronic biliary obstruction consequence of a bile duct injury may require liver transplantation (LT) in case of secondary biliary cirrhosis, intractable pruritus or reiterate episodes of cholangitis. \u201cMass-forming\u201d sclerosing cholangitis leading to secondary portal vein thrombosis and pre-sinusoidal portal hypertension has not been reported so far.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>PRESENTATION OF CASE:<\/jats:title>\n                    <jats:p>We present the case of a patient who underwent laparoscopic cholecystectomy for Mirizzi syndrome. The persistent bile duct obstruction due to a residual gallstone fragment was treated by a prolonged biliary stenting. Following repeated bouts of cholangitis, a fibrous centrohepatic scar developed, conglobating and obstructing the main branches of the portal vein and of the biliary tree. The patient developed secondary portal vein thrombosis and portal hypertension. After an extensive diagnostic work-up, including surgical exploration to rule out malignancy, the case was successfully managed by liver transplantation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>DISCUSSION:<\/jats:title>\n                    <jats:p>Mass-forming sclerosis of the bile duct and biliary bifurcation may develop as a consequence of chronic biliary obstruction and prolonged stenting. Secondary portal vein thrombosis and pre-sinusoidal portal hypertension represents an unusual complication, mimicking Klatskin tumor.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSION:<\/jats:title>\n                    <jats:p>A timely and proper management of post-cholecystectomy complications is of mainstay importance. Early referral to a specialized hepato-biliary center is strongly advised.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1016\/j.ijscr.2013.07.021","type":"journal-article","created":{"date-parts":[[2013,8,2]],"date-time":"2013-08-02T22:02:05Z","timestamp":1375480925000},"page":"907-910","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Liver transplantation for \u201cmass-forming\u201d sclerosing cholangitis after laparoscopic cholecystectomy"],"prefix":"10.1097","volume":"4","author":[{"given":"Damiano","family":"Patrono","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elena","family":"Mazza","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gianluca","family":"Paraluppi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paolo","family":"Strignano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ezio","family":"David","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Renato","family":"Romagnoli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mauro","family":"Salizzoni","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"R1-33-20260114","doi-asserted-by":"crossref","first-page":"1714","DOI":"10.1007\/s00268-008-9650-5","article-title":"Liver transplantation: the last measure in the treatment of bile duct injuries","volume":"32","author":"de Santibanes","year":"2008","journal-title":"World Journal of Surgery"},{"key":"R2-33-20260114","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1002\/lt.20021","article-title":"Laparoscopic iatrogeny of the hepatic hilum as an indication for liver transplantation","volume":"10","author":"Fernandez","year":"2004","journal-title":"Liver Transplantation"},{"key":"R3-33-20260114","doi-asserted-by":"crossref","first-page":"1360","DOI":"10.1007\/s00268-001-0124-2","article-title":"Surgical therapy of iatrogenic lesions of biliary tract","volume":"25","author":"Ahrendt","year":"2001","journal-title":"World Journal of Surgery"},{"key":"R4-33-20260114","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1111\/j.1477-2574.2010.00172.x","article-title":"Hepatic resection for post-cholecystectomy bile duct injuries: a literature review","volume":"12","author":"Truant","year":"2010","journal-title":"HPB (Oxford"},{"key":"R5-33-20260114","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1080\/13651820701883114","article-title":"Complex bile duct injuries: management","volume":"10","author":"de Santibanes","year":"2008","journal-title":"HPB (Oxford"},{"key":"R6-33-20260114","doi-asserted-by":"crossref","first-page":"2363","DOI":"10.1007\/s00268-007-9234-9","article-title":"Liver resection and transplantation in the management of iatrogenic biliary injury","volume":"31","author":"Thomson","year":"2007","journal-title":"World Journal of Surgery"},{"key":"R7-33-20260114","doi-asserted-by":"crossref","first-page":"4639","DOI":"10.3748\/wjg.v18.i34.4639","article-title":"Mirizzi syndrome: history, current knowledge and proposal of a simplified classification","volume":"18","author":"Beltran","year":"2012","journal-title":"World Journal of Gastroenterology"},{"key":"R8-33-20260114","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1016\/j.jamcollsurg.2011.03.008","article-title":"Diagnosis and treatment of Mirizzi syndrome: 23-year Mayo Clinic experience","volume":"213","author":"Erben","year":"2011","journal-title":"Journal of the American College of Surgeons"},{"key":"R9-33-20260114","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1007\/s00464-009-0520-5","article-title":"Laparoscopic treatment of Mirizzi syndrome: a systematic review","volume":"24","author":"Antoniou","year":"2010","journal-title":"Surgical Endoscopy"},{"key":"R10-33-20260114","doi-asserted-by":"crossref","first-page":"2626","DOI":"10.1007\/s00464-010-0966-5","article-title":"inside approach of the gallbladder is an alternative to the classic Calot's triangle dissection for a safe operation in severe cholecystitis","volume":"24","author":"Hubert","year":"2010","journal-title":"Surgical Endoscopy"},{"key":"R11-33-20260114","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1016\/j.jamcollsurg.2006.12.005","article-title":"Preoperative diagnosis and efficacy of laparoscopic procedures in the treatment of Mirizzi syndrome","volume":"204","author":"Kwon","year":"2007","journal-title":"Journal of the American College of Surgeons"},{"key":"R12-33-20260114","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1016\/j.jamcollsurg.2010.02.053","article-title":"Rationale and use of the critical view of safety in laparoscopic cholecystectomy","volume":"211","author":"Strasberg","year":"2010","journal-title":"Journal of the American College of Surgeons"},{"key":"R13-33-20260114","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1016\/j.jamcollsurg.2007.01.038","article-title":"Role of intraoperative cholangiography in avoiding bile duct injury","volume":"204","author":"Massarweh","year":"2007","journal-title":"Journal of the American College of 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