{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,14]],"date-time":"2026-01-14T23:56:53Z","timestamp":1768435013160,"version":"3.49.0"},"reference-count":8,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","license":[{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,10,17]],"date-time":"2013-10-17T00:00:00Z","timestamp":1381968000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/3.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2014,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>INTRODUCTION:<\/jats:title>\n                    <jats:p>Malignant epithelioid hemangioendothelioma (EHE) is an uncommon and grave vascular tumor. EHE is frequently angiocentric and is associated with a medium sized vessel, especially a vein. No definite etiological associations have been ascribed to this tumor so far, except an association with oral contraceptives in EHE of liver.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>PRESENTATION OF CASE:<\/jats:title>\n                    <jats:p>A 47 year old man presented with the complaint of intermittent black stool over the past two weeks. Occasionally, he experienced pain in left lower abdomen. On Computed Tomography (CT), it showed hypervascular lesion in the ileum with persistent enhancement. An exploratory laparotomy was performed with short segmental resection and functional end-to-end anastomosis. It was diagnosed finally with the histopathological and immunohistochemical analysis as a malignant EHE.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>DISCUSSION:<\/jats:title>\n                    <jats:p>EHE is an uncommon endothelial tumor that most frequently arises in soft tissue, liver, lung and skeleton. It behaves biologically in between benign epithelioid hemangioma and the more aggressive epithelioid angiosarcoma. Although a standard systemic treatment for malignant EHE has not been fully established, complete surgical excision is strongly recommended if feasible.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSION:<\/jats:title>\n                    <jats:p>EHE has a variable presentation and CT is helpful in identifying ileal EHE timely in the early stage, even when there is no obvious mass formation, however the diagnosis can be confirmed only after histopathological and immunohistochemical studies.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1016\/j.ijscr.2013.09.019","type":"journal-article","created":{"date-parts":[[2013,11,26]],"date-time":"2013-11-26T19:47:18Z","timestamp":1385495238000},"page":"19-21","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":2,"title":["Ileal malignant hemangioendothelioma as a hypervascular lesion on computed tomography scan"],"prefix":"10.1097","volume":"5","author":[{"given":"Hang","family":"Li","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Deepa","family":"Shah","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abhishek","family":"Shah","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiang","family":"Qiu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dianbo","family":"Cao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"R1-6-20260114","doi-asserted-by":"crossref","first-page":"558","DOI":"10.7150\/ijms.8.558","article-title":"Multicentric epithelioid hemangioendothelioma involving the same lower extremity: a case report and review of literature","volume":"8","author":"Liu","year":"2011","journal-title":"Int J Med Sci"},{"key":"R2-6-20260114","doi-asserted-by":"crossref","first-page":"640","DOI":"10.1136\/jcp.45.7.640","article-title":"Epithelioid hemangioendothelioma of soft tissue after pellet injury","volume":"45","author":"Sarma","year":"1992","journal-title":"J Clin Pathol"},{"key":"R3-6-20260114","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1007\/BF02471569","article-title":"A case of hemangioendothelioma of the small intestine","volume":"19","author":"Yasuda","year":"1989","journal-title":"Jpn J Surg"},{"key":"R4-6-20260114","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1016\/0002-9610(62)90226-X","article-title":"Tumors of the small intestine. A review of experience with 115 cases including a report of a rare case of malignant hemangioendothelioma","volume":"103","author":"Botsford","year":"1962","journal-title":"Am J Surg"},{"key":"R5-6-20260114","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1136\/jcp.42.8.889","article-title":"Epithelioid hemangioendothelioma of terminal ileum after therapeutic irradiation","volume":"42","author":"Akosa","year":"1989","journal-title":"J Clin Pathol"},{"key":"R6-6-20260114","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1007\/s12105-007-0035-0","article-title":"Epithelioid hemangioendothelioma of the head and neck: role of podoplanin in the differential diagnosis","volume":"2","author":"Naqvi","year":"2008","journal-title":"Head Neck Pathol"},{"key":"R7-6-20260114","doi-asserted-by":"crossref","first-page":"2108","DOI":"10.1002\/cncr.22225","article-title":"Primary malignant hepatic epithelioid hemangioendothelioma: a comprehensive review of the literature with emphasis on the surgical therapy","volume":"107","author":"Mehrabi","year":"2006","journal-title":"Cancer"},{"key":"R8-6-20260114","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1007\/s00261-003-0042-x","article-title":"Rare diffuse peritoneal malignant neoplasms: CT findings in two cases","volume":"28","author":"Mainenti","year":"2003","journal-title":"Abdom Imaging"}],"container-title":["International Journal of Surgery Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2210261213003143?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2210261213003143?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.lww.com\/01612930-201405010-00006","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,14]],"date-time":"2026-01-14T13:39:30Z","timestamp":1768397970000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/01612930-201405010-00006"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,1]]},"references-count":8,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2014]]}},"URL":"https:\/\/doi.org\/10.1016\/j.ijscr.2013.09.019","relation":{},"ISSN":["2210-2612"],"issn-type":[{"value":"2210-2612","type":"print"}],"subject":[],"published":{"date-parts":[[2014,1]]}}}