{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,3]],"date-time":"2026-11-03T05:43:38Z","timestamp":1793684618055,"version":"4.5.1"},"reference-count":10,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","license":[{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,12,7]],"date-time":"2013-12-07T00:00:00Z","timestamp":1386374400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/3.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2014,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>INTRODUCTION:<\/jats:title>\n                    <jats:p>Epstein-Barr virus positive inflammatory pseudo-tumour (IPT) of the spleen is an uncommon, frequently asymptomatic entity, which is typically picked up as an incidental finding on imaging.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>PRESENTATION OF CASE:<\/jats:title>\n                    <jats:p>We present a case of EBV positive IPT of the spleen which presented as an incidental finding on CT in a patient with a history of malignancy. Splenectomy was performed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>DISCUSSION:<\/jats:title>\n                    <jats:p>IPTs are benign spindle cell lesions of varying aetiology, which can arise in a variety of tissues, including the spleen. In situ hybridisation showed strong staining for Epstein-Barr virus RNA in our case, in common with many similar lesions described in the literature. The differential diagnosis of such spindle cell tumours is discussed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSION:<\/jats:title>\n                    <jats:p>Radiologically, EBV positive spindle cell tumours are indistinguishable from malignant lesions such as lymphoma and diagnosis is made on histology, usually at splenectomy.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1016\/j.ijscr.2013.12.006","type":"journal-article","created":{"date-parts":[[2014,2,14]],"date-time":"2014-02-14T14:17:28Z","timestamp":1392387448000},"page":"186-188","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":9,"title":["Epstein-Barr virus positive inflammatory pseudo-tumour of the spleen"],"prefix":"10.1097","volume":"5","author":[{"given":"P.","family":"Loughlin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Brady","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Devlin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.T.","family":"McManus","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.A.J.","family":"Spence","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-4-20260221","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1102\/1470-7330.2005.0002","article-title":"Tumours of the spleen","volume":"25","author":"Giovagnoni","year":"2005","journal-title":"Cancer Imaging"},{"key":"R2-4-20260221","doi-asserted-by":"crossref","first-page":"90","DOI":"10.3748\/wjg.v18.i1.90","article-title":"Inflammatory pseudotumor of the liver and spleen diagnosed by percutaneous needle biopsy","volume":"18","author":"Kawaguchi","year":"2012","journal-title":"World J Gastroenterol"},{"key":"R3-4-20260221","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1111\/j.1440-1827.2004.01589.x","article-title":"Inflammatory pseudotumor-like follicular dendritic cell tumor of the spleen","volume":"54","author":"Horiguchi","year":"2004","journal-title":"Pathol Int"},{"key":"R4-4-20260221","doi-asserted-by":"crossref","first-page":"1093","DOI":"10.1016\/0046-8177(95)90271-6","article-title":"Frequent presence of the Epstein-Barr virus in inflammatory pseudotumour","volume":"26","author":"Arber","year":"1995","journal-title":"Hum Pathol"},{"key":"R5-4-20260221","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1097\/00004836-200010000-00018","article-title":"A case of hemangioma accompanied by inflammatory pseudotumor of the spleen","volume":"31","author":"Matsubayashi","year":"2000","journal-title":"J Clin Gastroenterol"},{"key":"R6-4-20260221","doi-asserted-by":"crossref","first-page":"379","DOI":"10.5858\/2001-125-0379-SIMTIP","article-title":"Splenic inflammatory myofibroblastic tumor (inflammatory pseudotumor). A clinicopathologic and immunophenotypic study of 12 cases","volume":"125","author":"Neuhauser","year":"2001","journal-title":"Arch Pathol Lab Med"},{"key":"R7-4-20260221","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1097\/00000478-200106000-00003","article-title":"Inflammatory pseudotumor-like follicular dendritic cell tumor: a distinctive low-grade malignant intra-abdominal neoplasm with consistent Epstein-Barr virus association","volume":"25","author":"Cheuk","year":"2001","journal-title":"Am J Surg Pathol"},{"key":"R8-4-20260221","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1016\/S0740-2570(03)00014-5","article-title":"Two splenic lesions in need of clarification: hamartoma and inflammatory pseudotumor","volume":"20","author":"Krishnan","year":"2003","journal-title":"Semin Diagn Pathol"},{"key":"R9-4-20260221","doi-asserted-by":"crossref","first-page":"e67","DOI":"10.1259\/bjr\/66918927","article-title":"Epstein-Barr virus-positive inflammatory pseudotumor and inflammatory pseudotumor-like follicular dendritic cell tumor","volume":"82","author":"Kiryu","year":"2009","journal-title":"Br J Radiol"},{"key":"R10-4-20260221","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1007\/s12308-009-0030-3","article-title":"Epstein-Barr virus-associated inflammatory pseudotumor of the spleen: report of two cases and review of the literature","volume":"2","author":"Rosenbaum","year":"2009","journal-title":"J Hematopathol"}],"container-title":["International Journal of Surgery Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2210261213003519?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2210261213003519?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.lww.com\/01612930-201405040-00004","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,21]],"date-time":"2026-02-21T14:00:15Z","timestamp":1771682415000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/01612930-201405040-00004"}},"subtitle":["A case report and literature review"],"short-title":[],"issued":{"date-parts":[[2014,1]]},"references-count":10,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2014]]}},"URL":"https:\/\/doi.org\/10.1016\/j.ijscr.2013.12.006","relation":{},"ISSN":["2210-2612"],"issn-type":[{"value":"2210-2612","type":"print"}],"subject":[],"published":{"date-parts":[[2014,1]]}}}