{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T13:18:09Z","timestamp":1793798289838,"version":"4.6.1"},"reference-count":12,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","license":[{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,12,20]],"date-time":"2013-12-20T00:00:00Z","timestamp":1387497600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/3.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2014,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>INTRODUCTION:<\/jats:title>\n                    <jats:p>Rupture of blood vessels associated with neurofibromatosis type 1 (NF-1) is a rare but life threatening complication. We report the first case of an aneurysmal rupture from the costocervical trunk in a NF-1 patient treated by endovascular embolisation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>PRESENTATION OF CASE:<\/jats:title>\n                    <jats:p>A 43 year-old gentleman with a past medical history of NF-1 presented with sudden onset left sided neck swelling. A computed tomography (CT) revealed a large cervical haematoma, which was causing airway compromise, requiring the patient to be intubated. Percutaneous embolisation of the bleeding vessel from the costo-cervical trunk was performed with successful haemostasis and no immediate complications. A repeat CT scan showed a reduction in the original cervical haematoma. However, six days post embolisation, the patient arrested with complete whiteout of the left hemithorax.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>DISCUSSION:<\/jats:title>\n                    <jats:p>CT angiography is the gold standard for diagnosis of an aneurysmal rupture in NF-1 patients, and percutaneous embolisation is the preferred modality in patients who are haemodynamically stable due to arterial fragility and high intra operative mortality rates. The increasing haemothorax could be explained by the original cervical haematoma draining down into the pleural space, or the possibility of a new second bleed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSION:<\/jats:title>\n                    <jats:p>This is the first reported episode of bleeding from the costocervical trunk in NF-1 patients. Ruptured aneurysms require urgent CT angiography, if haemodynamically stable, and further input from the vascular surgeons and vascular radiologists.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1016\/j.ijscr.2013.12.023","type":"journal-article","created":{"date-parts":[[2014,1,3]],"date-time":"2014-01-03T02:31:26Z","timestamp":1388716286000},"page":"100-103","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":12,"title":["Aneurysmal rupture of the costo-cervical trunk in a patient with neurofibromatosis type 1"],"prefix":"10.1097","volume":"5","author":[{"given":"Bhupinder","family":"Hoonjan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nagendra","family":"Thayur","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdusalam","family":"Abu-Own","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-18-20260114","doi-asserted-by":"crossref","first-page":"86","DOI":"10.3348\/kjr.2013.14.1.86","article-title":"Spontaneous massive hemothorax in a patient with neurofibromatosis type 1 with successful transarterial embolization","volume":"14","author":"Hongsakul","year":"2013","journal-title":"Korean J Radiol"},{"key":"R2-18-20260114","first-page":"20","article-title":"Precise localization of NF1 to 17q11.2 by balanced translocation","volume":"44","author":"Ledbetter","year":"1989","journal-title":"Am J Hum 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artery in a patient with neurofibromatosis: a case report","volume":"15","author":"Ishizu","year":"2006","journal-title":"Cardiovasc Pathol"},{"key":"R7-18-20260114","doi-asserted-by":"crossref","first-page":"997","DOI":"10.1007\/s00234-007-0293-2","article-title":"Multislice CT angiography in the selection of patients with ruptured intracranial aneurysms suitable for clipping or coiling","volume":"49","author":"Westerlaan","year":"2007","journal-title":"Neuroradiology"},{"key":"R8-18-20260114","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1259\/bjr\/47379807","article-title":"Endovascular therapy for massive haemothorax caused by ruptured extracranial vertebral artery aneurysm with neurofibromatosis type 1","volume":"80","author":"Hieda","year":"2007","journal-title":"Br J Radiol"},{"key":"R9-18-20260114","doi-asserted-by":"crossref","first-page":"1230","DOI":"10.1067\/mtc.2002.124264","article-title":"Percutaneous treatment of a ruptured intercostal aneurysm presenting as massive hemothorax in a patient with type I neurofibromatosis","volume":"124","author":"Dominguez","year":"2002","journal-title":"J Thorac Cardiovasc Surg"},{"key":"R10-18-20260114","doi-asserted-by":"crossref","first-page":"1062","DOI":"10.1016\/S1010-7940(03)00145-3","article-title":"Spontaneous hemothorax associated with von Recklinghausen's disease","volume":"23","author":"Pezzetta","year":"2003","journal-title":"Eur J Cardiothorac Surg"},{"key":"R11-18-20260114","first-page":"286","article-title":"Spontaneous hemothorax caused by a ruptured interostal artery aneurysm in von Recklinghausen's neurofibromatosis","volume":"104","author":"Chang","year":"2005","journal-title":"J Formos Med Assoc"},{"key":"R12-18-20260114","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1177\/021849230701500417","article-title":"Spontaneous hemothorax and neurofibromatosis: a review of a lethal combination","volume":"15","author":"Fedoruk","year":"2007","journal-title":"Asian Cardiovasc Thorac 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