{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,31]],"date-time":"2026-03-31T02:41:41Z","timestamp":1774924901372,"version":"3.50.1"},"reference-count":20,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"7","license":[{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2014,2,11]],"date-time":"2014-02-11T00:00:00Z","timestamp":1392076800000},"content-version":"vor","delay-in-days":41,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/3.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2014,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>INTRODUCTION:<\/jats:title>\n                    <jats:p>Chordomas are rare but aggressive tumors due to local recurrence and distant metastases. They originate commonly in the sphenooccipital and sacrococcygeal regions, and metastasize to the lungs, bone, skin, liver, and lymph nodes. They occur more frequently in men and people over the age of 40.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>PRESENTATION OF CASE:<\/jats:title>\n                    <jats:p>A 28 year-old female presented with sacrococcygeal chordoma for which she received wide local excision and adjuvant radiation therapy. She enjoyed an unusual disease-free survival for 11 years until a routine surveillance scan of the pelvis identified local recurrence. Further work up revealed bilateral pulmonary metastases. She underwent local excision of the recurrent tumor and video-assisted thoracoscopic (VATS) wedge resection of pulmonary metastases. She also received adjuvant radiation therapy to the recurrent resection bed. Two years later, she remains free of disease and symptoms.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>DISCUSSION:<\/jats:title>\n                    <jats:p>Chordomas are commonly insensitive to chemotherapy and radiation, making surgery the most successful therapeutic modality. However, there are few guidelines on the surveillance and treatment of recurrent chordoma. We report success with aggressive surgical resection of recurrence and metastasis as well as adjuvant radiation therapy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSION:<\/jats:title>\n                    <jats:p>The prolonged survival of our patient underscores the importance of (1) aggressive surgical resection of chordoma, whether primary, recurrent, or metastatic, with adjuvant radiation therapy, (2) minimization of surgical seeding of tumor, and (3) diligent cancer surveillance.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1016\/j.ijscr.2014.02.005","type":"journal-article","created":{"date-parts":[[2014,5,1]],"date-time":"2014-05-01T21:01:17Z","timestamp":1398978077000},"page":"424-427","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":8,"title":["Case report"],"prefix":"10.1097","volume":"5","author":[{"given":"Cherie P.","family":"Erkmen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard J.","family":"Barth","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vignesh","family":"Raman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"R1-21-20260114","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1097\/00000478-198303000-00006","article-title":"A clinicopathologic review of 25 cases of chordoma (a pleomorphic and metastasizing neoplasm)","volume":"7","author":"Volpe","year":"1983","journal-title":"Am J Surg Pathol"},{"key":"R2-21-20260114","first-page":"1","article-title":"Chordoma: incidence and survival patterns in the United States, 1973-1995","volume":"12","author":"McMaster","year":"2001","journal-title":"Cancer Causes Control"},{"key":"R3-21-20260114","doi-asserted-by":"crossref","first-page":"277","DOI":"10.3171\/spi.2006.5.4.277","article-title":"Metastatic disease from spinal chordoma: a 10-year experience","volume":"5","author":"McPherson","year":"2006","journal-title":"J Neurosurg Spine"},{"key":"R4-21-20260114","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1007\/s12094-008-0243-4","article-title":"Metastatic disease from chordoma","volume":"10","author":"Vergara","year":"2008","journal-title":"Clin Transl Oncol"},{"key":"R5-21-20260114","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1093\/ajcp\/72.5.765","article-title":"Chordoma. 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A report of two autopsy cases with a review of the literature","volume":"42","author":"Fukuda","year":"1992","journal-title":"Acta Pathol Jpn"},{"key":"R8-21-20260114","doi-asserted-by":"crossref","first-page":"652","DOI":"10.1302\/0301-620X.90B5.20365","article-title":"Dedifferentiated chordoma: a report of four cases arising \u201cde novo\u201d","volume":"90-B","author":"Hanna","year":"2008","journal-title":"J Bone Joint Surg Br"},{"key":"R9-21-20260114","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1007\/s002560000264","article-title":"Sarcomatoid chordoma: chordoma with a massive malignant spindle-cell component","volume":"29","author":"Morimitsu","year":"2000","journal-title":"Skeletal Radiol"},{"key":"R10-21-20260114","doi-asserted-by":"crossref","first-page":"2233","DOI":"10.1097\/BRS.0b013e3181b61b90","article-title":"Long-term clinical outcomes following en bloc resections for sacral chordomas and chondrosarcomas: a series of twenty consecutive patients","volume":"34","author":"Hsieh","year":"2009","journal-title":"Spine"},{"key":"R11-21-20260114","doi-asserted-by":"crossref","first-page":"1569","DOI":"10.1097\/00007632-199607010-00017","article-title":"Chordoma of the spine above the sacrum. 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