{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T16:17:15Z","timestamp":1773073035436,"version":"3.50.1"},"reference-count":4,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"5","license":[{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2014,2,18]],"date-time":"2014-02-18T00:00:00Z","timestamp":1392681600000},"content-version":"vor","delay-in-days":48,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/3.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2014,1]]},"abstract":"ABSTRACT<\/jats:title>\n \n INTRODUCTION:<\/jats:title>\n Positron Emission Tomography - Computed Tomography (PET-CT) is routinely utilized in the management of melanoma, either as a part of staging workup or during surveillance. Since melanomas have a high metastatic potential, any FDG avid lesion is considered suspicious for recurrence. We report a case of a FDG avid lesion, diagnosed during melanoma surveillance, its management and review of literature.<\/jats:p>\n <\/jats:sec>\n \n PRESENTATION OF CASE:<\/jats:title>\n A 58 year-old-male underwent wide local excision for melanoma of the left cheek, and one year post-operatively a PET-CT that revealed a hypermetabolic focus in his right subscapularis muscle, which upon resection was diagnosed as Pigmented Villonodular Synovitis (PVNS).<\/jats:p>\n <\/jats:sec>\n \n DISCUSSION:<\/jats:title>\n PVNS is a rare benign giant cell tumor that requires no additional treatment in asymptomatic individuals. PET-CT is used for staging and surveillance of numerous malignancies, including melanoma. A hypermetabolic lesion on a PET-CT scan in the setting of malignancy is always suspicious for recurrence.<\/jats:p>\n <\/jats:sec>\n \n CONCLUSION:<\/jats:title>\n The surgeon is reminded of a uncommon benign FDG avid lesion. Typical location, nonspecific symptoms and characteristic imaging findings help cue in the diagnosis of PVNS and a tissue diagnosis will establish the diagnosis, thus avoiding unnecessarily aggressive surgical management.<\/jats:p>\n <\/jats:sec>","DOI":"10.1016\/j.ijscr.2014.02.009","type":"journal-article","created":{"date-parts":[[2014,2,26]],"date-time":"2014-02-26T20:01:05Z","timestamp":1393444865000},"page":"231-233","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":13,"title":["Pigmented villous nodular synovitis mimicking metastatic melanoma on PET-CT"],"prefix":"10.1097","volume":"5","author":[{"given":"Luke","family":"Selby","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Moshim","family":"Kukar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mansoor","family":"Beg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James","family":"Sullivan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"R1-5-20260114","doi-asserted-by":"crossref","first-page":"668","DOI":"10.1097\/01.rlu.0000079430.82897.b8","article-title":"Incidental detection of pigmented villonodular synovitis on FDG PET","volume":"28","author":"Kitapci","year":"2003","journal-title":"Clin Nucl Med"},{"key":"R2-5-20260114","doi-asserted-by":"crossref","first-page":"532","DOI":"10.1097\/RLU.0b013e3180646afb","article-title":"Localized nodular synovitis mimicking metastatic melanoma in a patient with metastatic melanoma on whole-body F-18 FDG PET\/CT with MRI and pathological correlation","volume":"32","author":"Mahmood","year":"2007","journal-title":"Clin Nucl Med"},{"key":"R3-5-20260114","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1053\/adpa.2003.50014","article-title":"Extensive pigmented villonodular synovitis with markedly pigmented lymphadenopathy and its implication for differential diagnosis with malignant melanoma","volume":"7","author":"Wang","year":"2003","journal-title":"Ann Diagn Pathol"},{"key":"R4-5-20260114","doi-asserted-by":"crossref","first-page":"376","DOI":"10.5435\/00124635-200606000-00007","article-title":"Pigmented villonodular synovitis","volume":"14","author":"Tyler","year":"2006","journal-title":"J Am Acad Orthop Surg"}],"container-title":["International Journal of Surgery Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S221026121400039X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S221026121400039X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.lww.com\/01612930-201405050-00005","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,14]],"date-time":"2026-01-14T13:19:25Z","timestamp":1768396765000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/01612930-201405050-00005"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,1]]},"references-count":4,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2014]]}},"URL":"https:\/\/doi.org\/10.1016\/j.ijscr.2014.02.009","relation":{},"ISSN":["2210-2612"],"issn-type":[{"value":"2210-2612","type":"print"}],"subject":[],"published":{"date-parts":[[2014,1]]}}}