{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,14]],"date-time":"2026-01-14T23:16:28Z","timestamp":1768432588786,"version":"3.49.0"},"reference-count":9,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"5","license":[{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2014,3,6]],"date-time":"2014-03-06T00:00:00Z","timestamp":1394064000000},"content-version":"vor","delay-in-days":64,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/3.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2014,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>INTRODUCTION:<\/jats:title>\n                    <jats:p>Ganglioneuromas are localized tumors derived from neural crest tissues. Characteristically, they originate in the posterior mediastinum. Pure adrenal gangliomas are extremely rare.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>PRESENTATION OF CASE:<\/jats:title>\n                    <jats:p>A left adrenal mass with the size of 68 mm \u00d7 50 mm \u00d7 86 mm on magnetic resonance imaging was documented in a 53-year-old female patient. Endocrine tests revealed a non-functioning adrenal mass. The actual size of the mass was macroscopically measured to be 16 cm \u00d7 8.5 cm \u00d7 6 cm after the surgery. Histopathological examination indicated ganglioneuroma.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>DISCUSSION:<\/jats:title>\n                    <jats:p>Most adrenal ganglioneuromas can incorrectly be diagnosed as other adrenal tumors, since they are rare neurogenic benign tumors with no specific imaging properties. They have a slow growth pattern and usually asymptomatic. Our case represents a huge adrenal ganglioneuroma in a female patient with nondiagnostic flank pain. Radiological imaging showed a large adrenal mass with no differentiation from other adrenal tumors. Endocrine evaluation should be performed for such adrenal masses. Since our case had a relatively large size, open surgery was preferred. Pathology revealed the definitive diagnosis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSION:<\/jats:title>\n                    <jats:p>This case suggests that ganglioneuromas can wrongly be diagnosed as other adrenal tumors. It is significant that a proper differential diagnosis should be performed by using hormonal and imaging techniques. Nevertheless, pathological examination is usually required for definitive diagnosis.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1016\/j.ijscr.2014.03.004","type":"journal-article","created":{"date-parts":[[2014,3,17]],"date-time":"2014-03-17T02:31:25Z","timestamp":1395023485000},"page":"253-255","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":5,"title":["Case report"],"prefix":"10.1097","volume":"5","author":[{"given":"Co\u015fkun","family":"Kacagan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ekrem","family":"Basaran","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Havva","family":"Erdem","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ali","family":"Tekin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ali","family":"Kayikci","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kamil","family":"Cam","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"R1-12-20260114","first-page":"10","article-title":"Three uncommon adrenal incidentalomas: a 13-year surgical pathology review","volume":"27","author":"Kanthan","year":"2012","journal-title":"World J Surg Oncol"},{"key":"R2-12-20260114","first-page":"191","article-title":"Adrenal incidentalomas: presentation and clinical work-up","volume":"68","author":"Beuschlein","year":"2007","journal-title":"Horm Res"},{"key":"R3-12-20260114","doi-asserted-by":"crossref","first-page":"2365","DOI":"10.2169\/internalmedicine.51.7726","article-title":"Large adrenal ganglioneuroma","volume":"51","author":"Sasaki","year":"2012","journal-title":"Intern Med"},{"key":"R4-12-20260114","first-page":"487","article-title":"Laparoscopic resection of large adrenal ganglioneuroma","volume":"11","author":"Zografos","year":"2007","journal-title":"JSLS"},{"key":"R5-12-20260114","doi-asserted-by":"crossref","first-page":"3118","DOI":"10.1210\/jc.2009-2775","article-title":"Clinical and biochemical features of seven adult adrenal ganglioneuromas","volume":"95","author":"Rondeau","year":"2010","journal-title":"J Clin Endocrinol Metab"},{"key":"R6-12-20260114","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/j.urology.2010.05.006","article-title":"Huge adrenal ganglioneuroma","volume":"78","author":"Lai","year":"2011","journal-title":"Urology"},{"key":"R7-12-20260114","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/j.annpat.2008.06.003","article-title":"Composite pheochromocytoma associated with multiple endocrine neoplasia type 2B","volume":"28","author":"Charfi","year":"2008","journal-title":"Ann Pathol"},{"key":"R8-12-20260114","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1016\/j.eururo.2010.06.024","article-title":"Laparoscopic versus open adrenalectomy for adrenocortical carcinoma: surgical and oncologic outcome in 152 patients","volume":"58","author":"Brix","year":"2010","journal-title":"Eur Urol"},{"key":"R9-12-20260114","first-page":"1110","article-title":"Diagnosis and treatment of 29 cases of adrenal ganglioneuroma","volume":"17","author":"Li","year":"2013","journal-title":"Eur Rev Med Pharmacol Sci"}],"container-title":["International Journal of Surgery Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2210261214000509?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2210261214000509?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.lww.com\/01612930-201405050-00012","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,14]],"date-time":"2026-01-14T13:18:13Z","timestamp":1768396693000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/01612930-201405050-00012"}},"subtitle":["Large adrenal ganglioneuroma"],"short-title":[],"issued":{"date-parts":[[2014,1]]},"references-count":9,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2014]]}},"URL":"https:\/\/doi.org\/10.1016\/j.ijscr.2014.03.004","relation":{},"ISSN":["2210-2612"],"issn-type":[{"value":"2210-2612","type":"print"}],"subject":[],"published":{"date-parts":[[2014,1]]}}}