{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,14]],"date-time":"2026-01-14T23:37:40Z","timestamp":1768433860590,"version":"3.49.0"},"reference-count":24,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"7","license":[{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2014,5,1]],"date-time":"2014-05-01T00:00:00Z","timestamp":1398902400000},"content-version":"vor","delay-in-days":120,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/3.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2014,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>INTRODUCTION:<\/jats:title>\n                    <jats:p>Nonpigmented villonodular synovitis (non-PVNS) is a benign proliferative disease involving the synovium. It is a rare condition that is little recognized. Non-PVNS has been reported as a cause of total knee replacement failure.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>PRESENTATION OF CASE:<\/jats:title>\n                    <jats:p>We report a case of extensive diffuse non-PVNS in a patient with tibial component loosening after total knee replacement and review the related literature.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>DISCUSSION:<\/jats:title>\n                    <jats:p>It is reported that pigmented villonodular synovitis (PVNS) occurs less frequently than non-PVNS after knee replacement. However, there are many more case reports of PVNS than non-PVNS after knee arthroplasty in the English-language literature.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSION:<\/jats:title>\n                    <jats:p>Previously, there were no reported cases of extensive diffuse non-PVNS after total knee arthroplasty (TKA). This case study highlights an unusual case of non-PVNS as a cause of TKA failure. We propose that non-PVNS should be considered as a differential diagnosis in patients after TKA who present with recurrent pain and effusion\/hemarthrosis of the knee, and that it is one of the causes of implant loosening after TKA.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1016\/j.ijscr.2014.04.031","type":"journal-article","created":{"date-parts":[[2014,5,13]],"date-time":"2014-05-13T18:45:32Z","timestamp":1400006732000},"page":"419-423","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":14,"title":["A rare case of extensive diffuse nonpigmented villonodular synovitis as a cause of total knee arthroplasty failure"],"prefix":"10.1097","volume":"5","author":[{"given":"Hac\u0131 Bayram","family":"Tosun","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abuzer","family":"Uluda\u011f","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sancar","family":"Serbest","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seyitali","family":"G\u00fcm\u00fc\u015fta\u015f","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u0130brahim Halil","family":"Erdo\u011fdu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"R1-20-20260114","first-page":"1659","article-title":"Pigmented villonodular synovitis: a disease in evolution","volume":"31","author":"Bouali","year":"2004","journal-title":"J Rheumatol"},{"key":"R2-20-20260114","first-page":"731","article-title":"Pigmented villonodular synovitis, bursitis and tenosynovitis","volume":"31","author":"Jaffe","year":"1941","journal-title":"Arch Pathol"},{"key":"R3-20-20260114","doi-asserted-by":"crossref","first-page":"978e9","DOI":"10.1016\/j.arth.2010.11.006","article-title":"A rare case of diffuse pigmented villonodular synovitis after total knee arthroplasty","volume":"26","author":"Oni","year":"2011","journal-title":"J Arthroplasty"},{"key":"R4-20-20260114","first-page":"185","article-title":"Cancer of the tendon sheath","volume":"47","author":"Chassaignac","year":"1852","journal-title":"Gaz Hop Civ Milit"},{"key":"R5-20-20260114","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1097\/00005792-198005000-00004","article-title":"Pigmented villonodular synovitis and tenosynovitis: a clinical epidemiologic study of 166 cases and literature review","volume":"59","author":"Myers","year":"1980","journal-title":"Medicine (Baltimore"},{"key":"R6-20-20260114","doi-asserted-by":"crossref","first-page":"1229","DOI":"10.1016\/j.arth.2006.11.022","article-title":"An unusual case of pigmented villonodular synovitis after total knee arthroplasty","volume":"22","author":"Bunting","year":"2007","journal-title":"J Arthroplasty"},{"key":"R7-20-20260114","first-page":"165","article-title":"Prosthesis-induced synovitis simulating villonodular synovitis","volume":"90","author":"Karl","year":"1991","journal-title":"Wis Med J"},{"key":"R8-20-20260114","doi-asserted-by":"crossref","first-page":"764","DOI":"10.2106\/00004623-199305000-00018","article-title":"Recurrent spontaneous hemarthrosis nine years after a total knee arthroplasty. 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