{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,15]],"date-time":"2026-01-15T00:21:05Z","timestamp":1768436465241,"version":"3.49.0"},"reference-count":15,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"8","license":[{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2014,6,11]],"date-time":"2014-06-11T00:00:00Z","timestamp":1402444800000},"content-version":"vor","delay-in-days":161,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/3.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2014,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>INTRODUCTION:<\/jats:title>\n                    <jats:p>Ochronosis is a rare disorder which is defined as the deposition of metabolites of oxidation and polymerization of homogentisic acid, which have high affinity to collogen, in the connective tissues. It is a clinical condition characterized with ochronotic pigmentation of tissues, degenerative arthropathy of especially large joints and black discoloration of urine. In this paper we present a case of ochronosis diagnosed with biopsy and additional tests when a black discoloration of menisci and joint cartilage were detected during arthroscopic intervention for a degenerative meniscus tear.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>PRESENTATION OF CASE:<\/jats:title>\n                    <jats:p>A forty two year-old male patient was operated for lateral meniscus tear of his right knee. The arthroscopic examination of right knee revealed black colored synovial hypertrophy and torn lateral meniscus. Partial meniscectomy was performed. The diagnosis of ochronosis was made after histopathologic examination.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>DISCUSSION:<\/jats:title>\n                    <jats:p>Ochronotic pigment can accumulate in hyaline cartilage, tendon, skin, teeth, nail, sclera, tympanic membrane, heart valves, renal tubular cells, duramater, pancreas and walls of large arteries. In ochronosis the most frequently involved joints are knee and hip. In ochronotic arthropathy, articular cartilage become more sensitive to mechanical stresses. Our patient had meniscal tear, cartilage damage and black discoloration of synovial tissues and meniscus.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSION:<\/jats:title>\n                    <jats:p>Arthroscopy may be helpful in diagnosis of ochronotic arthropathy.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1016\/j.ijscr.2014.06.007","type":"journal-article","created":{"date-parts":[[2014,6,16]],"date-time":"2014-06-16T18:25:06Z","timestamp":1402943106000},"page":"497-499","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":8,"title":["Ochronosis diagnosed after knee arthroscopy"],"prefix":"10.1097","volume":"5","author":[{"given":"Adnan","family":"Kara","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haluk","family":"Celik","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ali","family":"Seker","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hasan Basri","family":"Sezer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eray","family":"Kilinc","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Metin","family":"Uzun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"R1-18-20260114","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1007\/s00296-004-0498-1","article-title":"New developments in ochronosis: review of the literature","volume":"25","author":"Keller","year":"2005","journal-title":"Rheumatol Int"},{"key":"R2-18-20260114","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1007\/s00167-007-0413-x","article-title":"Ochronosis arthroscopy of a black knee: a case report and review of the literature","volume":"16","author":"Raaijmaakers","year":"2008","journal-title":"Knee Surg Sports Traumatol Arthrosc"},{"key":"R3-18-20260114","doi-asserted-by":"crossref","first-page":"778","DOI":"10.1007\/s00167-009-0778-0","article-title":"Osteoarthritis? Ochronotic arthritis! A case study and review of the literature","volume":"17","author":"Zhao","year":"2009","journal-title":"Knee Surg Sports Traumatol Arthrosc"},{"key":"R4-18-20260114","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1007\/s00167-009-0906-x","article-title":"Ochronosis: complicated tear of black meniscus","volume":"18","author":"Delialioglu","year":"2010","journal-title":"Knee Surg Sports Traumatol Arthrosc"},{"key":"R5-18-20260114","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1007\/s00296-004-0538-x","article-title":"Ochronotic arthritis: case reports and review of the literature","volume":"25","author":"Cetinus","year":"2005","journal-title":"Rheumatol Int"},{"key":"R6-18-20260114","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1302\/0301-620X.85B6.13662","article-title":"Spontaneous tendon ruptures in alkaptonuria","volume":"85","author":"Manoj Kumar","year":"2003","journal-title":"J Bone Joint Surg Br"},{"key":"R7-18-20260114","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1007\/s002640050325","article-title":"Ochronotic arthropathy: case report and review of the literature","volume":"23","author":"Hamdi","year":"1999","journal-title":"Int Orthop"},{"key":"R8-18-20260114","doi-asserted-by":"crossref","first-page":"67","DOI":"10.3944\/AOTT.2009.067","article-title":"Knee ochronotic arthropathy and arthroscopic findings","volume":"43","author":"Kural","year":"2009","journal-title":"Acta Orthop Traumatol Turc"},{"key":"R9-18-20260114","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/S0749-8063(03)00744-8","article-title":"Ochronotic arthropathy: arthroscopic findings in the shoulder and the knee","volume":"19","author":"Thacker","year":"2003","journal-title":"Arthroscopy"},{"key":"R10-18-20260114","first-page":"107","article-title":"Knee arthroscopy in a case of ochronotic arthropathy","volume":"18","author":"Tudisco","year":"1992","journal-title":"Ital J Orthop Traumatol"},{"key":"R11-18-20260114","first-page":"101","article-title":"Knee arthropathy in ochronosis: diagnosis by arthroscopy with ultrastructural features","volume":"11","author":"Lurie","year":"1984","journal-title":"J Rheumatol"},{"key":"R12-18-20260114","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1007\/s002960100136","article-title":"A case of ochronosis: upper extremity involvement","volume":"21","author":"Sahin","year":"2001","journal-title":"Rheumatol Int"},{"key":"R13-18-20260114","doi-asserted-by":"crossref","first-page":"2111","DOI":"10.1056\/NEJMoa021736","article-title":"Natural history of alkaptonuria","volume":"347","author":"Phornphutkul","year":"2002","journal-title":"N Engl J Med"},{"key":"R14-18-20260114","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1080\/00016470410001321","article-title":"Arthroplasty for ochronotic arthritis: no failure of 11 replacements in 3 patients followed 6-12 years","volume":"75","author":"Spencer","year":"2004","journal-title":"Acta Orthop Scand"},{"key":"R15-18-20260114","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1054\/arth.2000.4228","article-title":"Cementless total knee arthroplasty in ochronotic arthropathy: a case report with a 4-year follow-up","volume":"15","author":"Aydo\u011fdu","year":"2000","journal-title":"J Arthroplasty"}],"container-title":["International Journal of Surgery Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2210261214001382?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2210261214001382?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.lww.com\/01612930-201405080-00018","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,14]],"date-time":"2026-01-14T13:46:51Z","timestamp":1768398411000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/01612930-201405080-00018"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,1]]},"references-count":15,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2014]]}},"URL":"https:\/\/doi.org\/10.1016\/j.ijscr.2014.06.007","relation":{},"ISSN":["2210-2612"],"issn-type":[{"value":"2210-2612","type":"print"}],"subject":[],"published":{"date-parts":[[2014,1]]}}}