{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,25]],"date-time":"2026-03-25T22:51:27Z","timestamp":1774479087558,"version":"3.50.1"},"reference-count":25,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"10","license":[{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2014,9,5]],"date-time":"2014-09-05T00:00:00Z","timestamp":1409875200000},"content-version":"vor","delay-in-days":247,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/3.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2014,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>INTRODUCTION:<\/jats:title>\n                    <jats:p>Melanoma shows a particular predilection in involving small intestine both in a single site and in multiple localization and acute or chronic gastrointestinal bleedings are often the first sign of tumour.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>PRESENTATION OF CASE:<\/jats:title>\n                    <jats:p>We report two cases of GI metastases of malignant melanoma, one presented with only a big mass that cause intestinal obstruction and the other with a tumour spread throughout the small intestine that produce enterorrhagia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>DISCUSSION:<\/jats:title>\n                    <jats:p>Diagnosis and follow-up are very difficult: CT scan, PET-CT scan and capsule endoscopy should be complementary for the assessment of patients with GI symptoms and melanoma history.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSION:<\/jats:title>\n                    <jats:p>What is the role of surgery? Several studies suggest metastasectomy to achieve both R0 results and palliative resolutions of acute symptoms, such as obstruction, pain, and bleeding.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Highlights<\/jats:title>\n                  <\/jats:sec>","DOI":"10.1016\/j.ijscr.2014.09.003","type":"journal-article","created":{"date-parts":[[2014,9,10]],"date-time":"2014-09-10T07:22:43Z","timestamp":1410333763000},"page":"774-778","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":12,"title":["Gastrointestinal bleeding as presentation of small bowel metastases of malignant melanoma"],"prefix":"10.1097","volume":"5","author":[{"given":"Angelica","family":"Conversano","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Simona","family":"Macina","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rocco","family":"Indellicato","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Domenico","family":"Lacavalla","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dario","family":"D'Abbicco","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"R1-35-20260114","doi-asserted-by":"crossref","first-page":"969","DOI":"10.1001\/archsurg.1964.01310240065013","article-title":"Metastatic melanoma of the gastrointestinal tract","volume":"88","author":"Dasgupta","year":"1964","journal-title":"Arch Surg"},{"key":"R2-35-20260114","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1016\/0002-9610(78)90171-X","article-title":"Metastatic pattern of malignant melanoma: a study of 216 autopsy cases","volume":"135","author":"Patel","year":"1978","journal-title":"Am J Surg"},{"key":"R3-35-20260114","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1016\/0002-9610(91)90070-T","article-title":"Melanoma metastatic to stomach, small bowel, or colon","volume":"162","author":"Ihde","year":"1991","journal-title":"Am J Surg"},{"key":"R4-35-20260114","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1016\/j.ijscr.2012.03.033","article-title":"Intestinal melanoma: a broad spectrum of clinical presentation","volume":"3","author":"Patti","year":"2012","journal-title":"Int J Surg Case Rep"},{"key":"R5-35-20260114","doi-asserted-by":"crossref","first-page":"536","DOI":"10.12659\/AJCR.889670","article-title":"Early solitary small bowel metastasis from stage I cutaneous melanoma","volume":"14","author":"Gavriilidis","year":"2013","journal-title":"Am J Case Rep"},{"key":"R6-35-20260114","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1016\/S1470-2045(09)70036-1","article-title":"Melanoma of the small intestine","volume":"10","author":"Lens","year":"2009","journal-title":"Lancet Oncol"},{"key":"R7-35-20260114","first-page":"223","article-title":"Metastatic melanoma presenting as a perforated small bowel","volume":"17","author":"Alwhouhayb","year":"2006","journal-title":"Turk J Gastroenterol"},{"key":"R8-35-20260114","doi-asserted-by":"crossref","first-page":"2687","DOI":"10.3748\/wjg.v11.i17.2687","article-title":"Perforation of metastatic melanoma to the small bowel with simultaneous gastrointestinal stromal tumor","volume":"11","author":"Brummel","year":"2005","journal-title":"World J Gastroenterol"},{"key":"R9-35-20260114","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1002\/bjs.1800690407","article-title":"Acute complications of metastatic melanoma to the gastrointestinal tract","volume":"69","author":"Klausner","year":"1982","journal-title":"Br J Surg"},{"key":"R10-35-20260114","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1016\/j.ejso.2008.04.011","article-title":"Surgery for melanoma metastases of the gastrointestinal tract: indications and results","volume":"35","author":"Sanki","year":"2009","journal-title":"Eur J Surg Oncol"},{"key":"R11-35-20260114","doi-asserted-by":"crossref","first-page":"750","DOI":"10.1007\/s00268-001-0027-2","article-title":"Surgery for abdominal metastases of cutaneous melanoma","volume":"25","author":"Gutman","year":"2001","journal-title":"World J Surg"},{"key":"R12-35-20260114","doi-asserted-by":"crossref","first-page":"2392","DOI":"10.1016\/S0002-9270(01)02604-1","article-title":"Malignant melanoma: patterns of metastasis to the small bowel, reliability of imaging studies, and clinical relevance","volume":"96","author":"Bender","year":"2001","journal-title":"Am J Gastroenterol"},{"key":"R13-35-20260114","doi-asserted-by":"crossref","first-page":"646","DOI":"10.1007\/BF02574480","article-title":"Positron emission tomography is superior to computed tomography for metastatic detection in melanoma patients","volume":"9","author":"Swetter","year":"2002","journal-title":"Ann Surg Oncol"},{"key":"R14-35-20260114","doi-asserted-by":"crossref","first-page":"1178","DOI":"10.1200\/JCO.2005.03.5634","article-title":"Diagnostic performance of whole body dual modality 18F-FDG PET\/CT imaging for N- and M-staging of malignant melanoma: experience with 250 consecutive patients","volume":"24","author":"Reinhardt","year":"2006","journal-title":"J Clin Oncol"},{"key":"R15-35-20260114","doi-asserted-by":"crossref","first-page":"961","DOI":"10.1097\/01.rlu.0000099805.36471.aa","article-title":"The role of fluorine-18 deoxyglucose positron emission tomography in the management of patients with metastatic melanoma: impact on surgical decision making","volume":"28","author":"Gulec","year":"2003","journal-title":"Clin Nucl Med"},{"key":"R16-35-20260114","doi-asserted-by":"crossref","first-page":"1204","DOI":"10.1111\/j.1572-0241.2007.01115.x","article-title":"Capsule endoscopy in patients with malignant melanoma","volume":"102","author":"Prakoso","year":"2007","journal-title":"Am J Gastroenterol"},{"key":"R17-35-20260114","doi-asserted-by":"crossref","first-page":"490","DOI":"10.1055\/s-0030-1256357","article-title":"Algorithm for detection of small-bowel metastasis in malignant melanoma of the skin","volume":"43","author":"Albert","year":"2011","journal-title":"Endoscopy"},{"key":"R18-35-20260114","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1007\/s10434-999-0623-1","article-title":"Palliative surgery for stage IV melanoma: is it a primary treatment?","volume":"6","author":"Balch","year":"1999","journal-title":"Ann Surg Oncol"},{"key":"R19-35-20260114","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1016\/0002-9610(91)90254-B","article-title":"Role of surgical intervention in the management of intestinal metastases from malignant melanoma","volume":"162","author":"Branum","year":"1991","journal-title":"Am J Surg"},{"key":"R20-35-20260114","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1007\/s10434-999-0336-5","article-title":"Surgery for melanoma metastatic to the gastrointestinal tract","volume":"6","author":"Agrawal","year":"1999","journal-title":"Ann Surg Oncol"},{"key":"R21-35-20260114","first-page":"30","article-title":"Metastatic melanoma to the gastrointestinal tract: role of surgery as palliative treatment","volume":"109","author":"Shenoy","year":"2013","journal-title":"W V Med J"},{"key":"R22-35-20260114","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1007\/s12029-010-9180-x","article-title":"Metastatic malignant melanoma of the small bowel - report of two cases","volume":"43","author":"Sundersingh","year":"2012","journal-title":"J Gastrointest Cancer"},{"key":"R23-35-20260114","doi-asserted-by":"crossref","first-page":"e305","DOI":"10.1111\/j.1463-1318.2012.02940.x","article-title":"The role of surgery in the treatment of colorectal metastases from primary skin melanoma","volume":"14","author":"Szynglarewicz","year":"2012","journal-title":"Colorectal Dis"},{"key":"R24-35-20260114","doi-asserted-by":"crossref","first-page":"2205","DOI":"10.1517\/14656566.4.12.2205","article-title":"Systemic chemotherapy in the treatment of malignant melanoma","volume":"4","author":"Lens","year":"2003","journal-title":"Expert Opin Pharmacother"},{"key":"R25-35-20260114","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1097\/PPO.0b013e31824bc981","article-title":"Surgery for distant melanoma metastasis","volume":"18","author":"Leung","year":"2012","journal-title":"Cancer J"}],"container-title":["International Journal of Surgery Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2210261214002107?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2210261214002107?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.lww.com\/01612930-201405100-00035","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,14]],"date-time":"2026-01-14T13:17:00Z","timestamp":1768396620000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/01612930-201405100-00035"}},"subtitle":["Is surgery a good choice?"],"short-title":[],"issued":{"date-parts":[[2014,1]]},"references-count":25,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2014]]}},"URL":"https:\/\/doi.org\/10.1016\/j.ijscr.2014.09.003","relation":{},"ISSN":["2210-2612"],"issn-type":[{"value":"2210-2612","type":"print"}],"subject":[],"published":{"date-parts":[[2014,1]]}}}