{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,15]],"date-time":"2026-01-15T00:02:52Z","timestamp":1768435372799,"version":"3.49.0"},"reference-count":10,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"C","license":[{"start":{"date-parts":[[2015,1,1]],"date-time":"2015-01-01T00:00:00Z","timestamp":1420070400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2014,10,3]],"date-time":"2014-10-03T00:00:00Z","timestamp":1412294400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/3.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2015,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>INTRODUCTION<\/jats:title>\n                    <jats:p>We present a case of primary gastrointestinal tuberculosis that has culminated in ulcer formation, in the absence of pulmonary involvement in an immunocompetent patient.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>PRESENTATION OF CASE<\/jats:title>\n                    <jats:p>A 28-year-old Asian male presented to casualty with a 1-week history of epigastric cramping abdominal pain and several episodes of non-bilious vomiting. The patient deteriorated clinically, becoming more cachectic and given his unexplained weight loss, an oesophageal-gastro-duodenal endoscopic imaging confirmed a duodenal ulcer. The biopsy of the non-healing ulcer was the hallmark of the disease, revealing evidence of granulomatous inflammation consistent with tuberculosis bacilli.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>DISCUSSION<\/jats:title>\n                    <jats:p>Gastrointestinal tuberculosis with ulceration is rare with respect to the oesophagus, stomach and duodenum. This case proves to be unique, as our patient had experienced primary isolated gastric tuberculosis in the absence of pulmonary tuberculosis in a healthy individual. Immunohistochemical staining, histopathology and radiological investigations have demonstrated their importance in confirming abdominal tuberculosis and the extent of bowel involvement.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSION<\/jats:title>\n                    <jats:p>This case has illustrated the difficulties associated with a prompt diagnosis of an unusual case of primary duodenal tuberculosis from chronic peptic ulcer disease in an immunocompetent patient.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Highlights<\/jats:title>\n                  <\/jats:sec>","DOI":"10.1016\/j.ijscr.2014.09.028","type":"journal-article","created":{"date-parts":[[2014,11,22]],"date-time":"2014-11-22T10:47:42Z","timestamp":1416653262000},"page":"8-11","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":3,"title":["Non-healing gastro-duodenal ulcer"],"prefix":"10.1097","volume":"6","author":[{"given":"Nabeel","family":"Merali","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pankaj","family":"Chandak","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sudeendra","family":"Doddi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Prakash","family":"Sinha","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"R2-3-20260114","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1046\/j.1440-1746.1999.01844.x","article-title":"Isolated gastric tuberculosis of the cardia","volume":"14","author":"Lin","year":"1999","journal-title":"J Gastroenterol Hepatol"},{"key":"R3-3-20260114","doi-asserted-by":"crossref","first-page":"1074","DOI":"10.1097\/MEG.0b013e32834a9470","article-title":"Intestinal tuberculosis: a diagnostic challenge \u2013 case report and review of the literature","volume":"23","author":"Giouleme","year":"2011","journal-title":"Eur J Gastroenterol Hepatol"},{"key":"R4-3-20260114","first-page":"293","article-title":"Very rare presentation of extra pulmonary tuberculosis: primary gastric tuberculosis","volume":"58","author":"Kalac","year":"2010","journal-title":"Tuberk Toraks"},{"key":"R5-3-20260114","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/S0009-9260(88)80016-3","article-title":"Duodenal tuberculosis","volume":"39","author":"Gupta","year":"1988","journal-title":"Clin Radiol"},{"key":"R6-3-20260114","first-page":"345","article-title":"Tuberculosis of the large bowel. Report of two cases","volume":"150","author":"Knutson","year":"1984","journal-title":"Acta Clin Scan"},{"key":"R7-3-20260114","first-page":"345","article-title":"Gastrointestinal tuberculosis with cecum involvement in a 33-year-old woman","volume":"34","author":"Yadegarynia","year":"2009","journal-title":"IJMS"},{"key":"R8-3-20260114","doi-asserted-by":"crossref","first-page":"6371","DOI":"10.3748\/wjg.v12.i39.6371","article-title":"Diagnostic dilemma of abdominal tuberculosis in non-HIV patients: an ongoing challenge for physicians","volume":"12","author":"Khan","year":"2006","journal-title":"World J Gastroenterol"},{"key":"R9-3-20260114","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/0962-8479(95)90577-4","article-title":"Abdominal tuberculosis in Taiwan: a report from Veterans\u2019 General Hospital, Taipei","volume":"76","author":"Chen","year":"1995","journal-title":"Tuberc Lung Dis"},{"key":"R11-3-20260114","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1046\/j.1442-2034.1999.00017.x","article-title":"Abdominal tuberculosis revisited","volume":"3","author":"Faylona","year":"1999","journal-title":"Ann Coll Surg"},{"key":"R12-3-20260114","first-page":"36","article-title":"Laparoscopy in the complex diagnosis of abdominal and genital tuberculosis","volume":"3","author":"Semenovski","year":"1999","journal-title":"Probl Tuberk"}],"container-title":["International Journal of Surgery Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2210261214002387?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2210261214002387?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.lww.com\/01612930-201506000-00003","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,14]],"date-time":"2026-01-14T13:33:25Z","timestamp":1768397605000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/01612930-201506000-00003"}},"subtitle":["A rare presentation of primary abdominal tuberculosis"],"short-title":[],"issued":{"date-parts":[[2015,1]]},"references-count":10,"journal-issue":{"issue":"C","published-print":{"date-parts":[[2015]]}},"URL":"https:\/\/doi.org\/10.1016\/j.ijscr.2014.09.028","relation":{},"ISSN":["2210-2612"],"issn-type":[{"value":"2210-2612","type":"print"}],"subject":[],"published":{"date-parts":[[2015,1]]}}}