{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,15]],"date-time":"2026-01-15T00:05:24Z","timestamp":1768435524832,"version":"3.49.0"},"reference-count":15,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"C","license":[{"start":{"date-parts":[[2015,1,1]],"date-time":"2015-01-01T00:00:00Z","timestamp":1420070400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2015,10,10]],"date-time":"2015-10-10T00:00:00Z","timestamp":1444435200000},"content-version":"vor","delay-in-days":282,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2015,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>INTRODUCTION:<\/jats:title>\n                    <jats:p>Pyoderma gangrenosum (PG) is a rare, inflammatory skin pathology frequently associated with systemic inflammatory disease. While rare after surgery, recognition of this disease in the post-surgical setting is important as it can mimic wound infection.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>PRESENTATION OF CASE:<\/jats:title>\n                    <jats:p>We herein present a dramatic presentation of perianal PG four days after routine excision and fulguration of anal condyloma acuminatum. The affected area did not improve with broad spectrum antibiotics or surgical debridement. A diagnosis of PG was made from clinical suspicion and pathology findings, and further confirmed with rapid improvement after starting steroids. Diagnosis of this disease in the postoperative period requires high suspicion when the characteristic ulcerative or bullae lesions are seen diffusely and show minimal improvement with antibiotic treatment or debridement.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>DISCUSSION:<\/jats:title>\n                    <jats:p>Our case highlights the importance of recognizing this disease in the post-operative period, to allow for early initiation of appropriate treatment and prevent unnecessary surgical debridement of a highly sensitive area. There have been 32 case reports of PG in the colorectal literature, mostly following stoma creation. There is one case report of idiopathic perianal pyoderma gangrenosum with no known prior trauma. To our knowledge there are no previously reported cases of perianal PG after routine elective anorectal surgery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSION:<\/jats:title>\n                    <jats:p>This is the first reported case of perianal pyoderma gangrenosum in the post-surgical setting. Increased awareness of pyoderma gangrenosum in the surgical literature will aid in prompt diagnosis and proper medical management of this uncommon postoperative morbidity.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Highlights<\/jats:title>\n                  <\/jats:sec>","DOI":"10.1016\/j.ijscr.2015.10.010","type":"journal-article","created":{"date-parts":[[2015,10,25]],"date-time":"2015-10-25T11:50:06Z","timestamp":1445773806000},"page":"51-54","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":3,"title":["Perianal pyoderma gangrenosum after excision and fulguration of anal condyloma acuminatum"],"prefix":"10.1097","volume":"17","author":[{"given":"Jennifer L.","family":"Agnew","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul D.","family":"Strombom","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carmen F.","family":"Fong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Timothy J.","family":"Kelly","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joseph E.","family":"Martz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"R1-16-20260114","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1177\/0141076814534407","article-title":"Management of pyoderma gangrenosum","volume":"107","author":"Teagle","year":"2014","journal-title":"J. R. Soc. Med"},{"key":"R2-16-20260114","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/j.bjps.2014.12.036","article-title":"A systematic review of post-surgical pyoderma gangrenosum: identification of risk factors and proposed management strategy","volume":"68","author":"Zuo","year":"2015","journal-title":"J. Plast. Reconstr. Aesthet. Surg"},{"key":"R3-16-20260114","first-page":"e166","article-title":"Untreatable surgical site infection: consider pyoderma gangrenosum","volume":"2","author":"Berlinrut","year":"2014","journal-title":"Plast. Reconstr. Surg"},{"key":"R4-16-20260114","first-page":"e175","article-title":"Severe, Steroid-responsive, myositis mimicking necrotizing fasciitis following orthopedic surgery: a pyodermavariant with myonecrosis","volume":"2","author":"Reid","year":"2014","journal-title":"Plast. Reconstr. Surg"},{"key":"R5-16-20260114","doi-asserted-by":"crossref","first-page":"1347","DOI":"10.1007\/s00266-012-9981-3","article-title":"Postsurgical pyoderma gangrenosum complicating reduction mammoplasty","volume":"36","author":"Grillo","year":"2012","journal-title":"Aesthet. Plast. Surg"},{"key":"R6-16-20260114","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/j.ijscr.2014.06.010","article-title":"Pyoderma gangrenosum after cardiac surgery masquerading as a fulminant sternal wound infection","volume":"6C","author":"Suzuki","year":"2015","journal-title":"Int. J. Surg. Case Rep"},{"key":"R7-16-20260114","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1136\/bmj.292.6522.729","article-title":"Pyoderma gangrenosum after cholecystectomy","volume":"292","author":"Carr","year":"1986","journal-title":"Br. Med. J. (Clin. Res. Ed"},{"key":"R8-16-20260114","first-page":"E4","article-title":"Pyoderma gangrenosum following patellar tendon repair: a case report and review of the literature","volume":"41","author":"Wanich","year":"2012","journal-title":"Am. J. Orthop. (Belle Mead, NJ"},{"key":"R9-16-20260114","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1016\/S0001-7310(08)74720-3","article-title":"Pyoderma gangrenosum following cesarean delivery","volume":"99","author":"Sanz-Mu\u00f1oz","year":"2008","journal-title":"Actas Dermosifiliogr"},{"key":"R10-16-20260114","first-page":"894","article-title":"Fatal pyoderma gangrenosum after coronary artery bypass grafting","volume":"39","author":"Bryan","year":"2012","journal-title":"Tex Heart Inst. J"},{"key":"R11-16-20260114","doi-asserted-by":"crossref","first-page":"1186","DOI":"10.1001\/archsurg.1984.01390220064014","article-title":"Pyoderma gangrenosum at the parastomal site in patients with Crohn\u2019s disease","volume":"119","author":"McGarity","year":"1984","journal-title":"Arch. Surg"},{"key":"R12-16-20260114","doi-asserted-by":"crossref","first-page":"992","DOI":"10.1067\/mjd.2000.104515","article-title":"Parastomal pyoderma gangrenosum: clinical features and management","volume":"42","author":"Lyon","year":"2000","journal-title":"J. Am. Acad. Dermatol"},{"key":"R13-16-20260114","first-page":"248","article-title":"Pyoderma gangrenosum, rare parietal complication after colorectal surgery","volume":"109","author":"Miron","year":"2014","journal-title":"Chirurgia (Bucur"},{"key":"R14-16-20260114","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1111\/j.1346-8138.2006.00014.x","article-title":"Peristomal pyoderma gangrenosum associated with rectal adenocarcinoma","volume":"33","author":"Sakai","year":"2006","journal-title":"J. Dermatol"},{"key":"R15-16-20260114","doi-asserted-by":"crossref","first-page":"92","DOI":"10.4321\/S1130-01082012000200009","article-title":"Pyoderma gangrenosum with extensive perianal involvement","volume":"104","author":"Alvite-Canosa","year":"2012","journal-title":"Rev. Esp. Enferm. Dig"}],"container-title":["International Journal of Surgery Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2210261215004460?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2210261215004460?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.lww.com\/01612930-201517000-00016","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,14]],"date-time":"2026-01-14T13:38:46Z","timestamp":1768397926000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/01612930-201517000-00016"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,1]]},"references-count":15,"journal-issue":{"issue":"C","published-print":{"date-parts":[[2015]]}},"URL":"https:\/\/doi.org\/10.1016\/j.ijscr.2015.10.010","relation":{},"ISSN":["2210-2612"],"issn-type":[{"value":"2210-2612","type":"print"}],"subject":[],"published":{"date-parts":[[2015,1]]}}}