{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,14]],"date-time":"2026-01-14T23:46:03Z","timestamp":1768434363146,"version":"3.49.0"},"reference-count":12,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"C","license":[{"start":{"date-parts":[[2016,1,1]],"date-time":"2016-01-01T00:00:00Z","timestamp":1451606400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2016,1,19]],"date-time":"2016-01-19T00:00:00Z","timestamp":1453161600000},"content-version":"vor","delay-in-days":18,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2016,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>INTRODUCTION:<\/jats:title>\n                    <jats:p>Congenital melanocytic nevi (CMN) are present in 1\u20132% of newborn infants. The size of CMN defines the risk of developing melanoma which is estimated from 5\u201310%, especially in lesions that are located across the spine.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>PRESENTATION OF CASE:<\/jats:title>\n                    <jats:p>Herein we report a case where nodular melanoma was discovered on the periphery of medium sized CMN in a high risk patient. After complete excision, the defect was reconstructed with random pattern, triple rhomboid flap.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>DISCUSSION:<\/jats:title>\n                    <jats:p>Melanoma that arose within medium sized CMN would leave a complex posterior lower trunk defect. We used a triple Limberg flap which was proven to be straightforward and simple method when large defects are to be covered with vital tissue. We have also showed that this type of reconstruction is suitable for high risk patients that could not withstand any complex procedures.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSION:<\/jats:title>\n                    <jats:p>In our case, the method we choose to reconstruct the defect proved to be simple, safe and easy, especially when surgery is performed in a high risk patient.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Highlights<\/jats:title>\n                  <\/jats:sec>","DOI":"10.1016\/j.ijscr.2016.01.022","type":"journal-article","created":{"date-parts":[[2016,1,22]],"date-time":"2016-01-22T15:36:21Z","timestamp":1453476981000},"page":"84-86","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Case report of nodular melanoma within congenital melanocytic nevus- primary closure challenge"],"prefix":"10.1097","volume":"20","author":[{"given":"Domagoj","family":"Eljuga","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ivan","family":"Milas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Iva","family":"Kirac","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mladen","family":"Stanec","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Danko Velimir","family":"Vrdoljak","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"R1-24-20260114","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/j.jclinepi.2013.08.003","article-title":"The CARE guidelines: consensus-based clinical case report guideline development","volume":"67","author":"Gagnier","year":"2014","journal-title":"J. Clin. Epidemiol"},{"key":"R2-24-20260114","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/j.clindermatol.2010.04.004","article-title":"Congenital melanocytic nevi-when to worry and how to treat: facts and controversies","volume":"28","author":"Price","year":"2010","journal-title":"Clin. Dermatol"},{"key":"R3-24-20260114","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1016\/j.jaad.2012.05.043","article-title":"New recommendations for the categorization of cutaneous features of congenital melanocytic nevi","volume":"68","author":"Krengel","year":"2013","journal-title":"J. Am. Acad. Dermatol"},{"key":"R5-24-20260114","doi-asserted-by":"crossref","first-page":"782","DOI":"10.1097\/00006534-198106000-00012","article-title":"Nonepidermal origin of malignant melanoma associated with a giant congenital nevocellular nevus","volume":"67","author":"Rhodes","year":"1981","journal-title":"Plast. Reconstr. Surg"},{"key":"R6-24-20260114","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1016\/j.jaad.2005.02.024","article-title":"Large or multiple congenital melanocytic nevi: occurrence of cutaneous melanoma in 1008 persons","volume":"52","author":"Bett","year":"2005","journal-title":"J. Am. Acad. Dermatol"},{"key":"R7-24-20260114","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1590\/abd1806-4841.20132233","article-title":"Giant congenital melanocytic nevus","volume":"88","author":"Viana","year":"2013","journal-title":"An. Bras. Dermatol"},{"key":"R8-24-20260114","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/j.clindermatol.2010.04.004","article-title":"Congenital melanocytic nevi-when to worry and how to treat: facts and controversies","volume":"28","author":"Price","year":"2010","journal-title":"Clin. 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Dermatol"},{"key":"R11-24-20260114","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1159\/000090666","article-title":"Malignant melanoma in a large congenital melanocytic nevus 9 years after dermabrasion in childhood","volume":"212","author":"Dragieva","year":"2006","journal-title":"Dermatology"},{"key":"R13-24-20260114","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1097\/01.PRS.0000101534.00262.C6","article-title":"Design of the Limberg flap by a specially designed ruler: a personal approach","volume":"113","author":"Jovanovic","year":"2004","journal-title":"Plast. Reconstr. Surg"},{"key":"R14-24-20260114","doi-asserted-by":"crossref","first-page":"2446","DOI":"10.1097\/00006534-200206000-00042","article-title":"A subcostal artery perforator flap for a lumbar defect","volume":"109","author":"Feinendegen","year":"2002","journal-title":"Plast. Reconstr. 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