{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,14]],"date-time":"2026-01-14T23:21:25Z","timestamp":1768432885099,"version":"3.49.0"},"reference-count":10,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"C","license":[{"start":{"date-parts":[[2017,1,1]],"date-time":"2017-01-01T00:00:00Z","timestamp":1483228800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,1,7]],"date-time":"2017-01-07T00:00:00Z","timestamp":1483747200000},"content-version":"vor","delay-in-days":6,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2017,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>INTRODUCTION:<\/jats:title>\n                    <jats:p>Soft tissue mesenchymal tumours are a common occurrence in surgical practice with particular predilection for the extremities. Approximately 1 in 100 soft tissue tumours are found to be sarcomas. The main concern is to exclude any evidence of malignancy. Both imaging studies and a detailed histological analysis is required to ensure that a diagnosis of a high-grade tumour is not missed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>PRESENTATION OF CASE:<\/jats:title>\n                    <jats:p>Here we present a 38-year-old previously fit and well gentleman with a slowly growing lump in the upper aspect of his abdomen over the previous year being completely asymptomatic from it. He underwent ultrasound, computed tomography and magnetic resonance imaging of the lump. He underwent ultrasound guided biopsy with eventual wide local excision of the lump for a complete histological assessment. This was noted to be a soft tissue mesenchymal tumour.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>DISCUSSION:<\/jats:title>\n                    <jats:p>We highlight the importance of review of the literature and the use of markers that enable histopathologist reach an eventual diagnosis. Mesenchymal tissue during development differentiates into fat, skeletal muscle, peripheral nerves, blood vessels and fibrous tissue. Thereby any of these components may give rise to a tumour. In the majority of cases, the patient is asymptomatic unless there is invasion of nerve sheath or the effects of mass effect.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSION:<\/jats:title>\n                    <jats:p>Our case is unique due to location of the tumour and its immunohistochemistry findings which required frequent and extensive discussion at our national sarcoma soft tissue meeting. The importance of surgeons working with histopathologists was also highlighted in our case.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Highlights<\/jats:title>\n                  <\/jats:sec>","DOI":"10.1016\/j.ijscr.2017.01.013","type":"journal-article","created":{"date-parts":[[2017,1,12]],"date-time":"2017-01-12T15:02:01Z","timestamp":1484233321000},"page":"89-92","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Soft tissue mesenchymal tumour \u2013 a case report with review of literature"],"prefix":"10.1097","volume":"31","author":[{"given":"Debkumar","family":"Chowdhury","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michal","family":"Chudy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sanjeet","family":"Bhattacharya","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"R1-25-20260114","first-page":"13","article-title":"Management of patients with soft-tissue tumors Strategy developed at a regional oncology center","volume":"203","author":"Rydholm","year":"1983","journal-title":"Acta Orthop. Scand. Suppl"},{"key":"R2-25-20260114","first-page":"3","article-title":"Soft tissue sarcoma. Epidemiology and prognosis in 508 patients. Acta Orthop.","volume":"1-","author":"Gustafson","year":"1994","journal-title":"Scand"},{"key":"R3-25-20260114","first-page":"5","article-title":"Cancer statistics, 1996","volume":"46","author":"Parker","year":"1996","journal-title":"CA. Cancer J. Clin"},{"key":"R4-25-20260114","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1002\/(SICI)1097-0339(199710)17:4<298::AID-DC12>3.0.CO;2-J","article-title":"Malignant Peripheral Nerve Sheath Tumor: A Fine-Needle Aspiration Biopsy Study","volume":"17","author":"McGee","year":"2016","journal-title":"Diagn. Cytopathol"},{"key":"R5-25-20260114","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1002\/dc.20449","article-title":"Fine-needle aspiration of neurilemoma (Schwannoma). A clinicocytopathologic study of 116 patients","volume":"34","author":"Domanski","year":"2016","journal-title":"Diagn. Cytopathol"},{"key":"R6-25-20260114","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1046\/j.1440-1827.2000.01019.x","article-title":"Malignant peripheral nerve sheath tumor arising in benign ancient schwannoma: a case report with an immunohistochemical study","volume":"50","author":"Mikami","year":"2000","journal-title":"Pathol. Int"},{"key":"R7-25-20260114","doi-asserted-by":"crossref","first-page":"1266","DOI":"10.1002\/1097-0142(19900915)66:6<1266::AID-CNCR2820660628>3.0.CO;2-E","article-title":"Cellular schwannoma. A clinicopathological study of 57 patients and 58 tumors","volume":"66","author":"White","year":"1990","journal-title":"Cancer"},{"key":"R9-25-20260114","doi-asserted-by":"crossref","first-page":"ii89","DOI":"10.1093\/annonc\/mdn101","article-title":"Soft tissue sarcomas: ESMO clinical recommendations for diagnosis, treatment and follow-up","volume":"19","author":"Casali","year":"2008","journal-title":"Ann. Oncol"},{"key":"R10-25-20260114","first-page":"203","article-title":"Clinical features of soft tissue sarcomas","volume":"83","author":"Johnson","year":"2001","journal-title":"Ann. R. Coll. Surg. Engl"},{"key":"R11-25-20260114","doi-asserted-by":"crossref","first-page":"287","DOI":"10.3109\/17453678109050105","article-title":"A consecutive 7-year series of 1331 benign soft tissue tumours Clinicopathologic data. Comparison with sarcomas","volume":"52","author":"Myhre-Jensen","year":"1981","journal-title":"Acta Orthop. 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