{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,15]],"date-time":"2026-01-15T00:45:15Z","timestamp":1768437915832,"version":"3.49.0"},"reference-count":37,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"C","license":[{"start":{"date-parts":[[2017,1,1]],"date-time":"2017-01-01T00:00:00Z","timestamp":1483228800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,3,18]],"date-time":"2017-03-18T00:00:00Z","timestamp":1489795200000},"content-version":"vor","delay-in-days":76,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2017,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>INTRODUCTION:<\/jats:title>\n                    <jats:p>Gorham-Stout disease (GSD), or vanishing bone disease, is a very rare condition of unknown aetiology. It is characterised by progressive osteolysis and angiomatosis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CASE PRESENTATION:<\/jats:title>\n                    <jats:p>We report the discovery of this very rare disease following a trivial deciduous tooth extraction in a 14-year-old female. We focus initially on the difference between the preoperative orthopantomography and the whole-body computed tomography and magnetic resonance images obtained post-haemorrhage, and then on the improvement of strategies for the correct diagnosis and treatment of this disease.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>DISCUSSION:<\/jats:title>\n                    <jats:p>Bone loss and the proliferation of vascular structures can occur in a single bone or spread to soft tissue and adjacent bone; areas commonly affected by GSD include the ribs, spine, pelvis, skull, clavicle, and the maxillofacial area. The clinical presentation of GSD includes pain, functional impairment, and swelling, although a few asymptomatic cases have been reported, similar to our case.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSION:<\/jats:title>\n                    <jats:p>We report a very rare case of this multicentric disease in an asymptomatic child who presented for dental extraction, almost died, and was then diagnosed with and treated for GSD.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Highlights<\/jats:title>\n                  <\/jats:sec>","DOI":"10.1016\/j.ijscr.2017.03.028","type":"journal-article","created":{"date-parts":[[2017,3,21]],"date-time":"2017-03-21T14:20:37Z","timestamp":1490106037000},"page":"110-114","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":5,"title":["From tooth extraction to Gorham-Stout disease"],"prefix":"10.1097","volume":"34","author":[{"given":"Gabriele","family":"Bocchialini","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luca","family":"Ferrari","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dante","family":"Burlini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"R1-29-20260114","doi-asserted-by":"crossref","first-page":"813","DOI":"10.1007\/s10067-014-2780-2","article-title":"Gorham-Stout disease: radiological, histological, and clinical features of 12 cases and review of literature","volume":"35","author":"Liu","year":"2016","journal-title":"Clin. Rheumatol"},{"key":"R2-29-20260114","doi-asserted-by":"crossref","first-page":"624","DOI":"10.1002\/path.989","article-title":"Cellular and humoral mechanisms of osteoclast formation and bone resorption in Gorham-Stout disease","volume":"195","author":"Hirayama","year":"2001","journal-title":"J. Pathol"},{"key":"R3-29-20260114","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1007\/s10067-005-1088-7","article-title":"Massive Gorham-Stout syndrome of the pelvis","volume":"24","author":"Boyer","year":"2005","journal-title":"Clin. Rheumatol"},{"key":"R4-29-20260114","first-page":"368","article-title":"A boneless arm","volume":"18","author":"Jackson","year":"1838","journal-title":"Boston Med. Surg. J"},{"key":"R5-29-20260114","first-page":"245","article-title":"Absorption of the humerus after fractures","volume":"10","author":"Jackson","year":"1872","journal-title":"Boston Med. Surg. J"},{"key":"R7-29-20260114","doi-asserted-by":"crossref","first-page":"985","DOI":"10.2106\/00004623-195537050-00008","article-title":"Massive osteolysis (acute spontaneous absorption of bone, phantom bone, disappearing bone). Its relation to hemangiomatosis","volume":"37","author":"Gorham","year":"1955","journal-title":"J. Bone Joint Surg. Am"},{"key":"R8-29-20260114","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/j.ijscr.2017.01.061","article-title":"A massive haemorrhage developing during deciduous tooth extraction in a young child: a case report","volume":"31","author":"Bocchialini","year":"2017","journal-title":"Int. J. Surg. Case Rep"},{"key":"R9-29-20260114","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1016\/0030-4220(83)90185-8","article-title":"Perspectives on massive osteolysis. Report of a case and review of literature","volume":"55","author":"Heffez","year":"1983","journal-title":"Oral Surg. Oral Med. Oral Pathol"},{"key":"R10-29-20260114","first-page":"89","article-title":"The syndrome of idiopathic osteolysis: classification, review and case report","volume":"67","author":"Hardegger","year":"1985","journal-title":"J. Bone Joint Surg"},{"key":"R11-29-20260114","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1016\/S0022-3476(69)80395-1","article-title":"Hereditary multicentric osteolysis with recessive transmission: a new syndrome","volume":"75","author":"Torg","year":"1969","journal-title":"J. Pediatr"},{"key":"R12-29-20260114","first-page":"98","article-title":"Essential osteolysis with nephropathy","volume":"24","author":"Macpherson","year":"1973","journal-title":"J. Can. Assoc. Radiol"},{"key":"R13-29-20260114","doi-asserted-by":"crossref","first-page":"57","DOI":"10.2106\/00004623-197759010-00009","article-title":"Disappearing bone disease: a clinical and histological study","volume":"59","author":"Heyden","year":"1977","journal-title":"J. Bone Joint Surg. Am"},{"key":"R14-29-20260114","doi-asserted-by":"crossref","first-page":"917","DOI":"10.1007\/s00256-012-1565-4","article-title":"Gorham-Stout disease and generalized lymphatic anomaly \u2013 clinical, radiologic, and histologic differentiation","volume":"42","author":"Lala","year":"2013","journal-title":"Skeletal Radiol"},{"key":"R15-29-20260114","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1055\/s-2008-1033321","article-title":"The malignant degeneration of Gorham-Stout disease","volume":"155","author":"Fretz","year":"1991","journal-title":"Rofo"},{"key":"R16-29-20260114","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1007\/BF00182645","article-title":"Massive pelvic osteolysis in the Gorham-Stout syndrome","volume":"14","author":"Kulenkampff","year":"1990","journal-title":"Int. Orthop"},{"key":"R17-29-20260114","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1097\/00003086-197409000-00083","article-title":"Massive osteolysis: case report and review of literature","volume":"103","author":"Thompson","year":"1974","journal-title":"Clin. Orthop"},{"key":"R18-29-20260114","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/0221-8747(83)90001-2","article-title":"Progressive vertebral collapse in diffuse angiomatosis","volume":"5","author":"Young","year":"1983","journal-title":"Metab. Bone Dis. Relat. Res"},{"key":"R19-29-20260114","doi-asserted-by":"crossref","first-page":"1335","DOI":"10.2214\/ajr.154.6.2110757","article-title":"Musculoskeletal case of the day: gorham syndrome of the right clavicle and scapula","volume":"154","author":"Glass-Royal","year":"1990","journal-title":"AJR Am. J. Roentgenol"},{"key":"R20-29-20260114","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1007\/BF00538454","article-title":"Case report 803: Gorham's disease (Gorham-Stout syndrome) of scapula","volume":"22","author":"Damron","year":"1993","journal-title":"Skeletal Radiol"},{"key":"R21-29-20260114","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1378\/chest.92.1.189b","article-title":"Gorham's disease of the clavicle with bilateral pleural effusions. Eight years later","volume":"92","author":"Feigl","year":"1987","journal-title":"Chest"},{"key":"R22-29-20260114","doi-asserted-by":"crossref","first-page":"405","DOI":"10.2106\/00004623-197759030-00021","article-title":"Massive osteolysis of the scapula and ribs. A case report","volume":"59","author":"Sacristan","year":"1977","journal-title":"J. Bone Joint Surg. Am"},{"key":"R23-29-20260114","first-page":"671","article-title":"Successful treatment of a chylothorax in lymphangiomatosis of the ribs (Gorham-Stout syndrome)","volume":"119","author":"Romero","year":"1989","journal-title":"Schweiz. Med. Wochenschr"},{"key":"R24-29-20260114","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1007\/BF00444264","article-title":"Massive osteolysis of the pelvis, femur and sacral bone with a Gorham-Stout syndrome","volume":"114","author":"St\u00f6ve","year":"1995","journal-title":"Arch. Orthop. Trauma Surg"},{"key":"R25-29-20260114","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1097\/01241398-198909010-00019","article-title":"Massive osteolysis of the femur (Gorham's disease): a case report and review of the literature","volume":"9","author":"Mendez","year":"1989","journal-title":"J. Pediatr. Orthop"},{"key":"R26-29-20260114","doi-asserted-by":"crossref","first-page":"698","DOI":"10.1016\/0030-4220(90)90003-B","article-title":"Massive osteolysis of the maxillofacial bones: report of two cases","volume":"70","author":"Ohya","year":"1990","journal-title":"Oral Surg. Oral Med. Oral Pathol"},{"key":"R28-29-20260114","doi-asserted-by":"crossref","first-page":"904","DOI":"10.1093\/rheumatology\/38.9.904","article-title":"Gorham-Stout disease (phantom bone) of the shoulder girdle","volume":"38","author":"Hofbauer","year":"1999","journal-title":"Rheumatology (Oxford"},{"key":"R29-29-20260114","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1097\/01241398-198701000-00020","article-title":"Massive Gorham osteolysis of the right hemipelvis complicated by chylothorax: report of a case in a 9-year-old boy successfully treated by pleurodesis","volume":"7","author":"Hejgaard","year":"1987","journal-title":"J. Pediatr. Orthop"},{"key":"R30-29-20260114","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1631\/jzus.B1200308","article-title":"Gorham-Stout syndrome in mainland China: a case series of 67 patients and review of the literature","volume":"14","author":"Hu","year":"2013","journal-title":"J. Zhejiang Univ. Sci. B"},{"key":"R31-29-20260114","doi-asserted-by":"crossref","first-page":"985","DOI":"10.1097\/00004728-199411000-00028","article-title":"CT and MRI of gorham syndrome","volume":"18","author":"Vin\u00e9e","year":"1994","journal-title":"J. Comput. Assist. Tomogr"},{"key":"R32-29-20260114","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1046\/j.1365-2044.2000.055002157.x","article-title":"Gorham syndrome: anaesthetic management","volume":"55","author":"Szabo","year":"2000","journal-title":"Anaesthesia"},{"key":"R33-29-20260114","doi-asserted-by":"crossref","first-page":"782","DOI":"10.1016\/j.crad.2012.01.009","article-title":"Radiological features of Gorham's disease","volume":"67","author":"Kotecha","year":"2012","journal-title":"Clin. Radiol"},{"key":"R34-29-20260114","doi-asserted-by":"crossref","first-page":"1073","DOI":"10.1016\/j.joms.2007.06.677","article-title":"Multicentric Gorham's disease in the oral and maxillofacial region: report of a case and review of the literature","volume":"66","author":"Zhong","year":"2008","journal-title":"J. Oral Maxillofac. Surg"},{"key":"R35-29-20260114","doi-asserted-by":"crossref","first-page":"946","DOI":"10.3348\/kjr.2013.14.6.946","article-title":"A case of an idiopathic massive osteolysis with skip lesions","volume":"14","author":"Ozbayrak","year":"2013","journal-title":"Korean J. Radiol"},{"key":"R36-29-20260114","doi-asserted-by":"crossref","first-page":"957","DOI":"10.1016\/S0278-2391(03)00235-0","article-title":"Massive osteolysis of the mandible: a case report","volume":"61","author":"Motamedi","year":"2003","journal-title":"J. Oral Maxillofac. Surg"},{"key":"R37-29-20260114","doi-asserted-by":"crossref","first-page":"e41","DOI":"10.1016\/j.tripleo.2009.08.043","article-title":"Gorham-Stout syndrome: a rare clinical entity and review of literature","volume":"109","author":"Gondivkar","year":"2010","journal-title":"Oral Surg. Oral Med. Oral Pathol. Oral Radiol. Endod"},{"key":"R38-29-20260114","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1016\/j.ijsu.2016.08.014","article-title":"The SCARE statement: consensus-based surgical case report guidelines","volume":"34","author":"Agha","year":"2016","journal-title":"Int. J. Surg"},{"key":"R39-29-20260114","doi-asserted-by":"crossref","first-page":"694","DOI":"10.5312\/wjo.v5.i5.694","article-title":"Vanishing bone disease (Gorham-Stout syndrome): a review of a rare entity","volume":"5","author":"Nikolaou","year":"2014","journal-title":"World J Orthop"}],"container-title":["International Journal of Surgery Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2210261217301591?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2210261217301591?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.lww.com\/01612930-201734000-00029","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,14]],"date-time":"2026-01-14T13:49:44Z","timestamp":1768398584000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/01612930-201734000-00029"}},"subtitle":["A case report"],"short-title":[],"issued":{"date-parts":[[2017,1]]},"references-count":37,"journal-issue":{"issue":"C","published-print":{"date-parts":[[2017]]}},"URL":"https:\/\/doi.org\/10.1016\/j.ijscr.2017.03.028","relation":{},"ISSN":["2210-2612"],"issn-type":[{"value":"2210-2612","type":"print"}],"subject":[],"published":{"date-parts":[[2017,1]]}}}