{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,25]],"date-time":"2026-01-25T00:52:59Z","timestamp":1769302379348,"version":"3.49.0"},"reference-count":7,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"C","license":[{"start":{"date-parts":[[2018,1,1]],"date-time":"2018-01-01T00:00:00Z","timestamp":1514764800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,12,1]],"date-time":"2017-12-01T00:00:00Z","timestamp":1512086400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2018,1]]},"abstract":"ABSTRACT<\/jats:title>\n \n Objective:<\/jats:title>\n Marjolin's Ulcer (MU) is a rare cutaneous neoplasm arising in cikatrical tissue. Due to its typical clinical presentation as a non-healing lesion in scar tissue, the diagnosis can be delayed and even overlooked.<\/jats:p>\n <\/jats:sec>\n \n Methods and results:<\/jats:title>\n We present the case of an elderly woman who developed an ulcerated, exophytic lesion in a split thickness skin graft (STSG) on the lateral aspect of the left knee. Histology showed a radically excised highly differentiated squamous cell carcinoma (SCC) with keratine pearls and a component of basocellular carcinoma (BCC). The histological picture combined with the location and long time interval since the primary surgery made the diagnosis of MU highly likely.<\/jats:p>\n <\/jats:sec>\n \n Discussion:<\/jats:title>\n Considering the risk of metastasis and mortality it is important to recognize the diagnosis and initiate adequate treatment.<\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n The diagnosis of MU is clinical and confirmed by pathology. The typical long delay from the primary lesion to the malignant transformation might occlude the diagnosis. As such, a thorough anamnesis is essential in a non- healing ulcerated lesion in a cikatrical area to adequately diagnose and treat the condition.<\/jats:p>\n <\/jats:sec>\n \n Highlights<\/jats:title>\n <\/jats:sec>","DOI":"10.1016\/j.ijscr.2017.11.059","type":"journal-article","created":{"date-parts":[[2017,12,6]],"date-time":"2017-12-06T00:36:29Z","timestamp":1512520589000},"page":"102-103","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Marjolin's ulcer in a 20 years old split thickness skin graft on the knee\u2014A case report"],"prefix":"10.1097","volume":"42","author":[{"given":"Iselin","family":"Saltvig","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steen H.","family":"Matzen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"R2-26-20260114","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1016\/j.ijsu.2016.08.014","article-title":"The SCARE Statement: consensus-based surgical case report guidelines","volume":"34","author":"Agha","year":"2016","journal-title":"Int. J. Surg. (London, England"},{"key":"R3-26-20260114","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.1097\/BCR.0b013e31818ba0bf","article-title":"Marjolin's ulcer in an amputation stump","volume":"29","author":"Bloemsma","year":"2008","journal-title":"J. Burn Care Res"},{"key":"R4-26-20260114","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1097\/PRS.0b013e3181904d86","article-title":"Marjolin's ulcer: modern analysis of an ancient problem","volume":"123","author":"Kerr-Valentic","year":"2009","journal-title":"Plast. Reconstr. Surg"},{"key":"R5-26-20260114","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1016\/j.burns.2005.02.015","article-title":"Burn scar neoplasms: a literature review and statistical analysis","volume":"31","author":"Kowal-Vern","year":"2005","journal-title":"Burns: J. Int. Soc. Burn Inj"},{"key":"R6-26-20260114","first-page":"60","article-title":"A comprehensive review on Marjolin's ulcers: diagnosis and treatment","volume":"3","author":"Pekarek","year":"2011","journal-title":"J. Am. Coll. Certif. Wound Spec"},{"key":"R7-26-20260114","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1046\/j.1365-2230.2003.01210.x","article-title":"Thirty-one cases of Marjolin's ulcer","volume":"28","author":"Copcu","year":"2003","journal-title":"Clin. Exp. Dermatol"},{"key":"R8-26-20260114","first-page":"ic31","article-title":"Acute Marjolin's ulcer arising in a split-thickness skin graft postburn injury","volume":"16","author":"Moonsamy","year":"2016","journal-title":"Eplasty"}],"container-title":["International Journal of Surgery Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2210261217306387?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2210261217306387?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.lww.com\/01612930-201842000-00026","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,14]],"date-time":"2026-01-14T13:18:54Z","timestamp":1768396734000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/01612930-201842000-00026"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,1]]},"references-count":7,"journal-issue":{"issue":"C","published-print":{"date-parts":[[2018]]}},"URL":"https:\/\/doi.org\/10.1016\/j.ijscr.2017.11.059","relation":{},"ISSN":["2210-2612"],"issn-type":[{"value":"2210-2612","type":"print"}],"subject":[],"published":{"date-parts":[[2018,1]]}}}