{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T16:26:12Z","timestamp":1774542372442,"version":"3.50.1"},"reference-count":17,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"C","license":[{"start":{"date-parts":[[2018,1,1]],"date-time":"2018-01-01T00:00:00Z","timestamp":1514764800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,12,9]],"date-time":"2017-12-09T00:00:00Z","timestamp":1512777600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2018,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction:<\/jats:title>\n                    <jats:p>Malignant peripheral nerve sheath tumors (MPNST) are highly aggressive soft tissue sarcomas in which complete surgical resection is the mainstay of therapy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Clinical presentation:<\/jats:title>\n                    <jats:p>We report a case of MPNST, a 24 year old patient with right neck painful mass of 13 cm of greater dimension, skin spots, lentigos, cutaneous neurofibromas. The neck CT scan revealed a mass with liquid and soft tissues densities. Surgery was performed through right cervical Paul Andr\u00e9 incision and allowed exeresis of a hemorrhagic mass expensing on the cranial nerves X, XI, XII and the cervical sympathetic chain. Pathology analysis revealed a neurofibrosarcoma, the patient received six doses of chemotherapy. A second surgery was performed one year later after the appearance of a rapidly growing neck mass on the same site. The patient deceased in the intensive care unit one day post-op.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion:<\/jats:title>\n                    <jats:p>Neurofibrosarcoma is a rare clinical entity most often reported as case report. This tumor takes its origin from nerve structures such as the brachial plexus, the cervical sympathetic chain and the cranial nerves and their branches. The appearance of pain, size modification or signs of nerve root compression should warn us to search for a malignant degeneration. Surgery is the base of treatment, associated to radiotherapy and chemotherapy. Vinblastin and doxorubicin were used by other authors in association to radiotherapy with complete local control of inoperable tumors. The 5-year survival is 50% in patients with a neurofibrosarcoma de novo.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>The prognosis of neurofibrosarcoma is poor, prompting aggressive local (surgery) and systemic treatment (radiotherapy and\/or chemotherapy).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Highlights<\/jats:title>\n                  <\/jats:sec>","DOI":"10.1016\/j.ijscr.2017.12.019","type":"journal-article","created":{"date-parts":[[2017,12,12]],"date-time":"2017-12-12T03:55:54Z","timestamp":1513050954000},"page":"175-178","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["A case report of cervical neurofibrosarcoma"],"prefix":"10.1097","volume":"42","author":[{"given":"Asmaou","family":"Dalil","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Valentin","family":"Fokouo Fogha","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean","family":"Evehe Vokwely","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emery","family":"Sougou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J\u00e9r\u00f4me","family":"Miloundja","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"R1-41-20260114","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1016\/j.ijsu.2016.08.014","article-title":"The SCARE statement: consensus-based surgical case report guidelines","volume":"34","author":"Agha","year":"2016","journal-title":"Int. J. Surg"},{"key":"R2-41-20260114","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1016\/j.neurol.2007.07.006","article-title":"Montacer Kchir Nevralgie cervicobrachiale r\u00e9v\u00e9latrice d'un neurofibrosarcome (MPNST) cervical","volume":"164","author":"Tekaya","year":"2016","journal-title":"Rev. Neurol. (Paris"},{"key":"R3-41-20260114","first-page":"577","article-title":"Tumeurs malignes de la cavit\u00e9 buccale autres que les carcinomes spinocellulaires: un appercu","volume":"69","author":"Daby","year":"2003","journal-title":"J. Can. Dent. Assoc"},{"key":"R4-41-20260114","first-page":"271","article-title":"Neurogenic sarcoma of the head and neck with contact to the skull base","volume":"233","author":"Naujocks","year":"1981","journal-title":"Arch. Otorhinolaryngol"},{"key":"R6-41-20260114","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1001\/archotol.1979.00790170037010","article-title":"Neurogenic sarcoma of the head and neck","volume":"105","author":"Hutcherson","year":"1979","journal-title":"Arch. Otolaryngol"},{"key":"R7-41-20260114","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1093\/brain\/122.3.473","article-title":"Neurological complications or neurofibromatosis type 1 in adult hood","volume":"122","author":"Creange","year":"1999","journal-title":"Brain"},{"key":"R8-41-20260114","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1001\/archneur.1988.00520290115023","article-title":"Neurofibromatosis. conference statement","volume":"45","author":"National institute of health consensus development conference","year":"1988","journal-title":"Arch. Neurol"},{"key":"R9-41-20260114","first-page":"49","article-title":"Neurofibromatose 1: recommandations de prise en charge","volume":"9","author":"Pinson","year":"2002","journal-title":"ArchPediatr"},{"key":"R10-41-20260114","first-page":"107","article-title":"La neurofibromatose de type I ou maladie de Von Recklinghausen","volume":"5","author":"Rodriguez","year":"2002","journal-title":"Neurologies"},{"key":"R11-41-20260114","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1177\/197140099300600204","article-title":"Diagnostica neuroradiologica della facomatosis del sistema nervoso","volume":"6","author":"Dietemann","year":"1993","journal-title":"Rivista di neuroradiologia"},{"key":"R12-41-20260114","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1007\/s002470050605","article-title":"Cervical neurofibromatosis in children with NF1","volume":"29","author":"Chung","year":"1999","journal-title":"Pediatr. Radiol"},{"key":"R13-41-20260114","doi-asserted-by":"crossref","first-page":"1193","DOI":"10.2214\/ajr.158.6.1590106","article-title":"Lesions of skin and brain: modern imaging of the neurocutaneous syndromes","volume":"158","author":"Pont","year":"1992","journal-title":"AJR Am. J. Roentgenol"},{"key":"R14-41-20260114","doi-asserted-by":"crossref","first-page":"413","DOI":"10.2214\/ajr.180.2.1800413","article-title":"MR imaging of spinal tumours in children with neurofibromatosis 1","volume":"180","author":"Khong","year":"2003","journal-title":"AJR Am. J. Roentgenol"},{"key":"R15-41-20260114","doi-asserted-by":"crossref","first-page":"618","DOI":"10.1007\/s00234-003-0964-6","article-title":"Malignant peripheral nerve sheath tumours in neurofibromatosis type 1: MRI supports the diagnosis of malignant plexiform neurofibroma","volume":"45","author":"Mautner","year":"2003","journal-title":"Neuroradiology"},{"key":"R16-41-20260114","doi-asserted-by":"crossref","first-page":"1631","DOI":"10.2214\/ajr.173.6.10584812","article-title":"Thoracic manifestations of neurofibromatosis 1","volume":"173","author":"Rossi","year":"1999","journal-title":"AJR Am. J. Roentgenol"},{"key":"R17-41-20260114","first-page":"279","article-title":"Hernie colique lombaire secondaire \u00e0 des anomalies cong\u00e9nitales entrant dans le cadre d'une neurofibromatose de type I","volume":"77","author":"Rimmelin","year":"1996","journal-title":"J. Radiol"},{"key":"R18-41-20260114","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1159\/000276757","article-title":"Diagnosis and clinical outcome of neurogenic tumours in the head and neck area","volume":"57","author":"Kempf","year":"1995","journal-title":"Orl. J. Otorhinolaryngol. Relat. Spec"}],"container-title":["International Journal of Surgery Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2210261217306673?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2210261217306673?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.lww.com\/01612930-201842000-00041","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,14]],"date-time":"2026-01-14T13:14:24Z","timestamp":1768396464000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/01612930-201842000-00041"}},"subtitle":["Clinical presentation, treatment and outcome"],"short-title":[],"issued":{"date-parts":[[2018,1]]},"references-count":17,"journal-issue":{"issue":"C","published-print":{"date-parts":[[2018]]}},"URL":"https:\/\/doi.org\/10.1016\/j.ijscr.2017.12.019","relation":{},"ISSN":["2210-2612"],"issn-type":[{"value":"2210-2612","type":"print"}],"subject":[],"published":{"date-parts":[[2018,1]]}}}