{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,7]],"date-time":"2026-02-07T17:41:20Z","timestamp":1770486080062,"version":"3.49.0"},"reference-count":10,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"C","license":[{"start":{"date-parts":[[2018,1,1]],"date-time":"2018-01-01T00:00:00Z","timestamp":1514764800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,5,5]],"date-time":"2018-05-05T00:00:00Z","timestamp":1525478400000},"content-version":"vor","delay-in-days":124,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2018,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction:<\/jats:title>\n                    <jats:p>Primary lymphomas of appendix are extremely rare tumors. The incidence is 0.015% of all gastrointestinal lymphomas.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Presentation of case:<\/jats:title>\n                    <jats:p>We present a case of a 75 year-old male patient who presented with acute abdominal pain in the lower right quadrant and fever.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion:<\/jats:title>\n                    <jats:p>The patient received laparotomic appendectomy. The definitive histopathological examination revealed the presence of diffuse large cell B-lymphoma of the appendix. The neoplasms of appendix usually manifest clinically with sign and symptoms of acute appendicitis from luminal obstruction (30-50%). Preoperative diagnosis is difficult and often occurs through histopathological examination.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Primary appendiceal lymphoma is rare and there are no clear guidelines for therapy. Primary surgical resection followed by post-operative chemotherapy showed high efficacy. The histopathological examination of all appendectomy is essential.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Highlights<\/jats:title>\n                  <\/jats:sec>","DOI":"10.1016\/j.ijscr.2018.04.031","type":"journal-article","created":{"date-parts":[[2018,5,7]],"date-time":"2018-05-07T13:19:35Z","timestamp":1525699175000},"page":"30-33","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":9,"title":["Primary lymphoma of appendix presenting as acute appendicitis"],"prefix":"10.1097","volume":"48","author":[{"given":"Giuseppe","family":"Caristo","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guido","family":"Griseri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rosario","family":"Fornaro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonio","family":"Langone","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Angelo","family":"Franceschi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Veronica","family":"Errigo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cecilia","family":"Ferrari","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marco","family":"Casaccia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marco","family":"Frascio","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Angelo","family":"Schirru","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"R1-7-20260114","first-page":"79","article-title":"Primary malignant lymphoma of the appendix associated with acute appendicitis","volume":"16","author":"Shiwani","year":"2006","journal-title":"J. Coll. Phys. Surg. Pak"},{"key":"R2-7-20260114","first-page":"73","article-title":"Multiple intestinal lymphoma","volume":"53","author":"Mastalier","year":"2015","journal-title":"Rom. J. Intern. Med"},{"key":"R3-7-20260114","doi-asserted-by":"crossref","first-page":"1123","DOI":"10.2214\/ajr.178.5.1781123","article-title":"Non-Hodgkin's lymphoma of the appendix: clinical and CT findings with pathologic correlation","volume":"178","author":"Pickhardt","year":"2002","journal-title":"AJR Am. J. Roentgenol"},{"key":"R4-7-20260114","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1016\/j.ijsu.2016.08.014","article-title":"The SCARE statement: consensus-based surgical case report guidelines","volume":"34","author":"Agha","year":"2016","journal-title":"Int. J. Surg"},{"key":"R5-7-20260114","doi-asserted-by":"crossref","first-page":"392","DOI":"10.4103\/0377-4929.42523","article-title":"Primary marginal zone B-cell lymphoma of appendix","volume":"51","author":"Radha","year":"2008","journal-title":"Indian J. Pathol. Microbiol"},{"key":"R6-7-20260114","first-page":"619","article-title":"Intestinal invagination caused by primary lymphoma of the ileum","volume":"43","author":"Ferraris","year":"1988","journal-title":"Minerva Chir"},{"key":"R7-7-20260114","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1148\/rg.233025134","article-title":"Primary neoplasms of the appendix: radiologic spectrum of disease with pathologic correlation","volume":"23","author":"Pickhardt","year":"2003","journal-title":"Radiographics"},{"key":"R8-7-20260114","doi-asserted-by":"crossref","first-page":"W91","DOI":"10.2214\/AJR.09.2637","article-title":"Clinical utility of PET\/CT in lymphoma","volume":"194","author":"Cronin","year":"2010","journal-title":"AJR Am. J. Roentgenol"},{"key":"R9-7-20260114","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1016\/j.leukres.2006.06.018","article-title":"Prospective clinical study of surgical resection followed by CHOP in localized intestinal diffuse large B cell lymphoma","volume":"31","author":"Lee","year":"2007","journal-title":"Leuk. Res"},{"key":"R10-7-20260114","first-page":"629","article-title":"Primary appendiceal lymphoma presenting as perforated acute appendicitis","volume":"67","author":"Fu","year":"2004","journal-title":"J. Chin. Med. Assoc"}],"container-title":["International Journal of Surgery Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2210261218301573?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2210261218301573?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.lww.com\/01612930-201848000-00007","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,14]],"date-time":"2026-01-14T13:19:04Z","timestamp":1768396744000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/01612930-201848000-00007"}},"subtitle":["A case report"],"short-title":[],"issued":{"date-parts":[[2018,1]]},"references-count":10,"journal-issue":{"issue":"C","published-print":{"date-parts":[[2018]]}},"URL":"https:\/\/doi.org\/10.1016\/j.ijscr.2018.04.031","relation":{},"ISSN":["2210-2612"],"issn-type":[{"value":"2210-2612","type":"print"}],"subject":[],"published":{"date-parts":[[2018,1]]}}}