{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,14]],"date-time":"2026-01-14T23:27:46Z","timestamp":1768433266078,"version":"3.49.0"},"reference-count":28,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"C","license":[{"start":{"date-parts":[[2018,1,1]],"date-time":"2018-01-01T00:00:00Z","timestamp":1514764800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,8,7]],"date-time":"2018-08-07T00:00:00Z","timestamp":1533600000000},"content-version":"vor","delay-in-days":218,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2018,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction:<\/jats:title>\n                    <jats:p>Gastrointestinal metastases from pulmonary neoplasm represent a rare but potentially fatal pathology that can complicate the disease in most advanced stages; this is a rare but well-known phenomenon in Literature and small intestine is the most common metastatic site. Generally these are patients with a known or surgically treated pulmonary neoplasm; the onset of pulmonary neoplastic disease with a symptomatic intestinal metastasis is to be considered extremely rare.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Presentation of cases:<\/jats:title>\n                    <jats:p>We report two cases of small intestine perforation from pulmonary metastasis; diagnosis was made at the time of exploratory laparotomy and the operation was in one patient the resection of the perforated bowel and in the second a resection and an intestinal bypass to overcome the stenosis caused by the metastatic masses. In the postoperative period, a patient died of pulmonary complications, the second was dismissed, but survival was only three months.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion:<\/jats:title>\n                    <jats:p>Intestinal metastasis of a pulmonary tumor is a rare occurrence but must be suspected in acute abdominal syndrome in a patient with a diagnosed pulmonary neoplasia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Emergency surgical treatment of abdominal metastases of a lung cancer is mandatory but prognosis is extremely unfavorable.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Highlights<\/jats:title>\n                  <\/jats:sec>","DOI":"10.1016\/j.ijscr.2018.07.039","type":"journal-article","created":{"date-parts":[[2018,8,9]],"date-time":"2018-08-09T13:11:25Z","timestamp":1533820285000},"page":"331-334","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":6,"title":["Bowel perforation secondary to metastatic lung cancer"],"prefix":"10.1097","volume":"51","author":[{"given":"Alberto","family":"Garavello","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pietro","family":"Fransvea","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefano","family":"Rossi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesco","family":"Giacovazzo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vincenza","family":"Marino","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"R1-82-20260114","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/S0169-5002(99)00075-6","article-title":"Small bowel metastases in non-small cell lung cancer","volume":"26","author":"Stenbygaard","year":"1999","journal-title":"Lung Cancer"},{"key":"R2-82-20260114","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1177\/000313480507100204","article-title":"A case and review of bowel perforation secondary to metastatic lung cancer","volume":"71","author":"Gaewood","year":"2005","journal-title":"Am. Surg"},{"key":"R3-82-20260114","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1007\/s12029-011-9329-2","article-title":"Small Bowel perforation secondary to metastatic non-small cell lung cancer. A rare entity with dismal prognosis","volume":"43","author":"Salemis","year":"2012","journal-title":"J. Gastrointest. Cancer"},{"key":"R4-82-20260114","first-page":"687","article-title":"Perforation of a metastatic carcinoma of the jejunum after cancer chemotherapy","volume":"49","author":"Morgan","year":"1961","journal-title":"Surgery"},{"key":"R5-82-20260114","first-page":"631","article-title":"Small bowel perforation due to metastatic lung squamous cell carcinoma","volume":"28","author":"Yuksel","year":"2007","journal-title":"Saudi Med. J"},{"key":"R6-82-20260114","doi-asserted-by":"crossref","first-page":"1399","DOI":"10.3748\/wjg.v11.i9.1399","article-title":"Multiple metastases to the small bowel from large cell bronchial carcinomas","volume":"11","author":"Tomas","year":"2005","journal-title":"World J. Gastroenterol"},{"key":"R7-82-20260114","first-page":"677","article-title":"Small bowel metastases from primary lung carcinoma: a rarity waiting to be found?","volume":"58","author":"Mosier","year":"1992","journal-title":"Am. Surg"},{"key":"R8-82-20260114","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/S1556-0864(15)30037-X","article-title":"Primary lung cancer presenting with gastrointestinal tract involvement: clinicopathologic and immunohistochemical features in a series of 18 consecutive cases","volume":"2","author":"Rossi","year":"2007","journal-title":"J. Thorac. Oncol"},{"key":"R9-82-20260114","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1097\/00004728-198501000-00008","article-title":"Computed tomography of abdominal carcinoid tumor","volume":"9","author":"Cockey","year":"1985","journal-title":"J. Comput. Assist. Tomogr"},{"key":"R10-82-20260114","doi-asserted-by":"crossref","first-page":"1486","DOI":"10.1002\/1097-0142(19870415)59:8<1486::AID-CNCR2820590815>3.0.CO;2-W","article-title":"Small bowel metastases from primary carcinoma of the lung","volume":"59","author":"McNeill","year":"1987","journal-title":"Cancer"},{"key":"R11-82-20260114","doi-asserted-by":"crossref","first-page":"176","DOI":"10.9738\/1380.1","article-title":"A case of lung squamous cell carcinoma with metastases to the duodenum and small intestine","volume":"96","author":"Yamada","year":"2011","journal-title":"Int. Surg"},{"key":"R12-82-20260114","doi-asserted-by":"crossref","first-page":"4314","DOI":"10.3748\/wjg.v17.i38.4314","article-title":"Role of surgical intervention in managing gastrointestinal metastases from lung cancer","volume":"17","author":"Po-Chu","year":"2011","journal-title":"World Gastroenterol"},{"key":"R14-82-20260114","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1016\/S0761-8425(06)71578-9","article-title":"Metastases intestinales de carcinome broncho-pulmonaire","volume":"23","author":"Locher","year":"2006","journal-title":"Rev. Mal. Respir"},{"key":"R16-82-20260114","doi-asserted-by":"crossref","first-page":"1282","DOI":"10.3748\/wjg.v13.i8.1282","article-title":"Melena:a rare complication of duodenal metastases from primary carcinoma of the lung","volume":"13","author":"Kostakou","year":"2007","journal-title":"World J. Gastroenterol"},{"key":"R17-82-20260114","doi-asserted-by":"crossref","first-page":"1884","DOI":"10.1111\/j.1572-0241.1999.01224.x","article-title":"Small bowel metastases from primary carcinoma of the lung: clinical findings and outcome","volume":"94","author":"Berger","year":"1999","journal-title":"Am. J. Gastroenterol"},{"key":"R18-82-20260114","first-page":"566","article-title":"Surgical treatment for small bowel metastasis of pleomorphic carcinoma 6 months after pulmonary resection","volume":"65","author":"Oyama","year":"2012","journal-title":"Kiobu Geka"},{"key":"R19-82-20260114","first-page":"10","article-title":"Acute small bowel obstruction: a rare initial presentation for the metastasis of the large-cell carcinoma of the lung","volume":"29","author":"Song","year":"2012","journal-title":"World J. Surg. Oncol"},{"key":"R20-82-20260114","doi-asserted-by":"crossref","first-page":"4314","DOI":"10.3748\/wjg.v17.i38.4314","article-title":"Role of surgical intervention in managing gastrointestinal metastases from lung cancer","volume":"17","author":"Lee","year":"2011","journal-title":"World J. Gastroenterol"},{"key":"R21-82-20260114","first-page":"430","article-title":"Perforation of the small intestine caused by metastasis from primary lung cancer: report of two cases and the discussion of 48 cases published in the Japanese literature","volume":"45","author":"Nagashima","year":"2007","journal-title":"Nihon Kokyuki Gakkai Zasshi"},{"key":"R22-82-20260114","first-page":"621","article-title":"A case of lung cancer with small intestine metastasis with perforative peritonitis as the initial symptom","volume":"42","author":"Nakano","year":"2015","journal-title":"Gan To Kagaku Ryoho"},{"key":"R23-82-20260114","first-page":"856","article-title":"Small intestinal perforation due to metastasis from pulmonary pleomorphic carcinoma; report of a case","volume":"67","author":"Terada","year":"2014","journal-title":"Kyobu Geka"},{"key":"R24-82-20260114","first-page":"120","article-title":"Small bowel metastasis from lung cancer: a possible cause of acute abdomen. Case report and literature review","volume":"32","author":"Bugiantella","year":"2011","journal-title":"G. Chir"},{"key":"R25-82-20260114","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1177\/030089160609200218","article-title":"Abdominal metastases from lung cancer resulting in small bowel perforation: report of three cases","volume":"92","author":"Savanis","year":"2006","journal-title":"Tumori"},{"key":"R26-82-20260114","doi-asserted-by":"crossref","first-page":"141","DOI":"10.4103\/0377-4929.59208","article-title":"Intussusception due to intestinal metastasis from lung cancer","volume":"53","author":"Kini","year":"2010","journal-title":"Indian J. Pathol. Microbiol"},{"key":"R27-82-20260114","first-page":"782","article-title":"A rare case of intussusception associated with metastasized small cell carcinoma of the lung","volume":"50","author":"Jarmin","year":"2012","journal-title":"Acta Med. Iran"},{"key":"R28-82-20260114","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1007\/s00595-006-3419-y","article-title":"Laparotomy for acute complications of gastrointestinal metastases from lung cancer: is it a worthwhile or futile effort?","volume":"37","author":"Goh","year":"2007","journal-title":"Surg. Today"},{"key":"R29-82-20260114","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1007\/s00595-011-0005-8","article-title":"Surgical management of small bowel metastases from primary carcinoma of the lung","volume":"42","author":"Nishizawa","year":"2012","journal-title":"Surg. Today"},{"key":"R30-82-20260114","doi-asserted-by":"crossref","first-page":"748","DOI":"10.1007\/s11748-011-0811-3","article-title":"Surgical treatment for gastrointestinal metastasis of non-small-cell lung cancer after pulmonary resection","volume":"59","author":"Fujiwara","year":"2011","journal-title":"Gen. Thorac. Cardiovasc. Surg"}],"container-title":["International Journal of Surgery Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2210261218302931?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2210261218302931?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.lww.com\/01612930-201851000-00082","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,14]],"date-time":"2026-01-14T13:06:35Z","timestamp":1768395995000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/01612930-201851000-00082"}},"subtitle":["Report of two cases with literature review"],"short-title":[],"issued":{"date-parts":[[2018,1]]},"references-count":28,"journal-issue":{"issue":"C","published-print":{"date-parts":[[2018]]}},"URL":"https:\/\/doi.org\/10.1016\/j.ijscr.2018.07.039","relation":{},"ISSN":["2210-2612"],"issn-type":[{"value":"2210-2612","type":"print"}],"subject":[],"published":{"date-parts":[[2018,1]]}}}