{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,28]],"date-time":"2026-02-28T10:40:56Z","timestamp":1772275256831,"version":"3.50.1"},"reference-count":7,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"C","license":[{"start":{"date-parts":[[2018,1,1]],"date-time":"2018-01-01T00:00:00Z","timestamp":1514764800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,9,15]],"date-time":"2018-09-15T00:00:00Z","timestamp":1536969600000},"content-version":"vor","delay-in-days":257,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2018,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction:<\/jats:title>\n                    <jats:p>Brown tumors are non-neoplastic, expansive bone lesions that occur only in the setting of hyperparathyroidism. The most usual localization of brown tumors is in mandible, ribs and large bones. In cervical spine, to date, there are only 11 cases reported. The aim of this work is to report the case of a patient with Wegener's granulomatosis with secondary end stage renal failure who developed a brown tumor in C4 vertebra.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Presentation of case:<\/jats:title>\n                    <jats:p>A 25-year-old woman with an history of 2 months of worsening cervicalgia without history of trauma. She complained about progressive neck pain with irradiation to both shoulders and right arm paresthesias, spontaneous fracture or brown spinal cord tumor were suspected. She presented cervical spine instability, was managed with corpectomy of C4 and biopsy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion:<\/jats:title>\n                    <jats:p>The initial suspicion of this disease must be since the first clinician contact of the patient and with the past medical history of end stage renal failure plus recent neurologic manifestations. The aim of neurosurgical management of these patients is to promote spinal stability and release spinal cord and nerve roots to eliminate risk of neurological deficits.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>The importance of the prompt diagnosis of the brown tumor is to establish a multidisciplinary management to prevent progression, neurologic complications and sequelae despite its benign behavior.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Highlights<\/jats:title>\n                  <\/jats:sec>","DOI":"10.1016\/j.ijscr.2018.09.023","type":"journal-article","created":{"date-parts":[[2018,9,17]],"date-time":"2018-09-17T22:41:35Z","timestamp":1537224095000},"page":"328-330","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":8,"title":["Brown tumor of the cervical spine in a patient with secondary hyperparathyroidism"],"prefix":"10.1097","volume":"51","author":[{"given":"Mauricio Daniel","family":"S\u00e1nchez-Calder\u00f3n","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Diego","family":"Ochoa-Cacique","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Oscar","family":"Medina Carrillo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ulises","family":"Garc\u00eda Gonz\u00e1lez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rosa Mar\u00eda","family":"Vicu\u00f1a Gonz\u00e1lez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlos Cesar","family":"Bravo Reyna","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9 Ra\u00fal","family":"Guerra-Mora","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"R1-81-20260114","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1080\/02688697.2016.1199789","article-title":"A thoracic vertebral brown tumor presenting with paraparesis in a patient with end-stage renal disease","volume":"31","author":"Solmaz","year":"2017","journal-title":"Br. J. Neurosurg"},{"key":"R2-81-20260114","doi-asserted-by":"crossref","first-page":"110","DOI":"10.4184\/asj.2015.9.1.110","article-title":"Brown tumor of the cervical spines: a case report with literature review","volume":"9","author":"Alfawareh","year":"2015","journal-title":"Asian Spine J"},{"key":"R3-81-20260114","first-page":"242","article-title":"Chronic renal failure causing brown tumors and myelopathy. Case report and review of pathophysiology and treatment","volume":"90","author":"Fineman","year":"1999","journal-title":"J. Neurosurg"},{"key":"R4-81-20260114","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1007\/s11255-010-9738-3","article-title":"Unusual clinical presentation of brown tumor in hemodialysis patients: two case reports","volume":"43","author":"Resic","year":"2011","journal-title":"Int. Urol. Nephrol"},{"key":"R6-81-20260114","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1016\/j.ijsu.2016.08.014","article-title":"The SCARE statement: consensus-based surgical case report guidelines","volume":"34","author":"Agha","year":"2016","journal-title":"Int. J. Surg"},{"key":"R7-81-20260114","doi-asserted-by":"crossref","first-page":"936","DOI":"10.1097\/00007632-199306000-00023","article-title":"Brown tumor of the cervical spine","volume":"18","author":"Barlow","year":"1993","journal-title":"Spine (Phila Pa 1976"},{"key":"R8-81-20260114","doi-asserted-by":"crossref","first-page":"110","DOI":"10.4103\/0028-3886.152680","article-title":"Cervical burst fracture caused by brown tumor","volume":"63","author":"Aydemir","year":"2015","journal-title":"Neurol. India"}],"container-title":["International Journal of Surgery Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2210261218303894?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2210261218303894?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.lww.com\/01612930-201851000-00081","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,14]],"date-time":"2026-01-14T13:06:05Z","timestamp":1768395965000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/01612930-201851000-00081"}},"subtitle":["A case report"],"short-title":[],"issued":{"date-parts":[[2018,1]]},"references-count":7,"journal-issue":{"issue":"C","published-print":{"date-parts":[[2018]]}},"URL":"https:\/\/doi.org\/10.1016\/j.ijscr.2018.09.023","relation":{},"ISSN":["2210-2612"],"issn-type":[{"value":"2210-2612","type":"print"}],"subject":[],"published":{"date-parts":[[2018,1]]}}}