{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,15]],"date-time":"2026-01-15T07:54:29Z","timestamp":1768463669671,"version":"3.49.0"},"reference-count":8,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"C","license":[{"start":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T00:00:00Z","timestamp":1546300800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,3,28]],"date-time":"2019-03-28T00:00:00Z","timestamp":1553731200000},"content-version":"vor","delay-in-days":86,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2019,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction:<\/jats:title>\n                    <jats:p>Cirrhosis is a risk factor for poor outcomes in non-hepatic oncological resections. There are only a handful of cases demonstrating outcomes of pancreaticoduodenectomy (PD) in patients with pancreatic cancer and underlying cirrhosis. Moreover, pushing the limits of PD to elderly cirrhotic patients and demonstrating its safety remains under reported.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case presentation:<\/jats:title>\n                    <jats:p>Here, we report successful management of a 71 year-old-lady with HCV related liver cirrhosis, obstructive jaundice and poor performance status, who was medically optimized and then underwent PD for adenocarcinoma of the head of pancreas. There was no major post-operative morbidity except minor chyle leak which resolved spontaneously. On her last follow up, she was doing well and undergoing adjuvant chemotherapy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion:<\/jats:title>\n                    <jats:p>Preoperative medical optimization and careful patient selection can yield successful outcomes even after a major abdominal surgery like PD in elderly patients with underlying liver cirrhosis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Liver cirrhosis is not a contra indication to PD in elderly patients with good performance status.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Highlights<\/jats:title>\n                  <\/jats:sec>","DOI":"10.1016\/j.ijscr.2019.03.034","type":"journal-article","created":{"date-parts":[[2019,4,10]],"date-time":"2019-04-10T11:29:57Z","timestamp":1554895797000},"page":"18-20","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":2,"title":["Successful outcome after Pancreaticodoudenectomy in an elderly cirrhotic patient"],"prefix":"10.1097","volume":"58","author":[{"given":"Eraj","family":"Sahaab","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nadeem","family":"Iqbal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abu Bakar Hafeez","family":"Bhatti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"R1-5-20260114","doi-asserted-by":"crossref","first-page":"e000042","DOI":"10.1136\/esmoopen-2016-000042","article-title":"Cancer and liver cirrhosis: implications on prognosis and management","volume":"1","author":"Pinter","year":"2016","journal-title":"ESMO Open"},{"key":"R2-5-20260114","first-page":"1","article-title":"Perioperative risk assessment and management of cirrhotic patients","volume":"1","author":"Simmelink","year":"2015","journal-title":"J. Hepatol. Gastroint. Dis"},{"key":"R3-5-20260114","doi-asserted-by":"crossref","first-page":"1261","DOI":"10.1053\/j.gastro.2007.01.040","article-title":"Risk factors for mortality after surgery in patients with cirrhosis","volume":"132","author":"Teh","year":"2007","journal-title":"Gastroenterology"},{"key":"R4-5-20260114","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1016\/j.ijsu.2018.10.028","article-title":"Statement: updating consensus Surgical CAse REport (SCARE) guidelines","volume":"2018","author":"Agha","year":"2018","journal-title":"Int. J. Surg"},{"key":"R5-5-20260114","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1016\/j.ciresp.2016.01.002","article-title":"Is pancreaticoduodenectomy a safe procedure in the cirrhotic patient?","volume":"94","author":"Busquets","year":"2016","journal-title":"Cir. Esp"},{"key":"R6-5-20260114","doi-asserted-by":"crossref","first-page":"7129","DOI":"10.3748\/wjg.v19.i41.7129","article-title":"Impact of cirrhosis on surgical outcome after pancreaticoduodenectomy","volume":"19","author":"Nakeeb","year":"2013","journal-title":"World J. Gastroenterol"},{"key":"R7-5-20260114","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/j.ijsu.2016.05.069","article-title":"Survival advantage with para aortic lymphadenectomy in peri-ampullary cancer: a retrospective cohort study","volume":"31","author":"Bhatti","year":"2016","journal-title":"Int. J. Surg"},{"key":"R8-5-20260114","doi-asserted-by":"crossref","first-page":"1111","DOI":"10.1007\/s00268-017-4259-1","article-title":"Living donor liver transplantation in South Asia: single center experience on intermediate-term outcomes","volume":"42","author":"Dar","year":"2018","journal-title":"World J. Surg"}],"container-title":["International Journal of Surgery Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2210261219301543?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2210261219301543?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.lww.com\/01612930-201958000-00005","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,14]],"date-time":"2026-01-14T13:07:05Z","timestamp":1768396025000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/01612930-201958000-00005"}},"subtitle":["A case report"],"short-title":[],"issued":{"date-parts":[[2019,1]]},"references-count":8,"journal-issue":{"issue":"C","published-print":{"date-parts":[[2019]]}},"URL":"https:\/\/doi.org\/10.1016\/j.ijscr.2019.03.034","relation":{},"ISSN":["2210-2612"],"issn-type":[{"value":"2210-2612","type":"print"}],"subject":[],"published":{"date-parts":[[2019,1]]}}}