{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T19:11:27Z","timestamp":1789153887697,"version":"build-2803163510"},"reference-count":12,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"C","license":[{"start":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T00:00:00Z","timestamp":1546300800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,4,18]],"date-time":"2019-04-18T00:00:00Z","timestamp":1555545600000},"content-version":"vor","delay-in-days":107,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2019,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction:<\/jats:title>\n                    <jats:p>Boerhaave's syndrome is a life-threatening oesophageal perforation that carries a high mortality rate (20-50%). Diagnosis is difficult by its rarity and the absence of typical symptoms. Treatment of this condition usually requires surgical intervention.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Presentation of case:<\/jats:title>\n                    <jats:p>We report the case of a 77-year-old man that resorted to the emergency room with dyspnoea and thoracic pain after vomiting. CT scan revealed pneumomediastinum, left collapse lung and loculated pleural effusion. A left intercostal chest tube was inserted with food drainage. Hence, Boerhaave's syndrome was suspected. Thoracotomy with mediastinum debridement, pleural drainage and oesophageal T-tube drainage was performed. Patient was admitted on the Intensive Care Unit with septic shock, with need for ventilatory support and vasopressor therapy. Two days later, a second look thoracotomy was done with definitive oesophageal repair and pleural patch. The post-operative course was complicated by pneumonia and stroke. Patient was discharged home on the 38th day and remains well at 3 month of follow-up.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion:<\/jats:title>\n                    <jats:p>Delayed diagnosis and treatment are the principal causes of high mortality in Boerhaave's syndrome. The classic Mackler's triad (vomiting, lower thoracic pain and subcutaneous emphysema) is present in less then 50% of cases. A thoracic drainage may be useful to confirm diagnosis promptly. There is no standard treatment option. In this case report, the authors used a damage control approach to control sepsis, allowing for a delayed definitive oesophageal repair.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Prompt diagnosis with thoracic drainage and a damage control treatment plan might lead to good prognosis for patients with this rare and potentially fatal condition.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Highlights<\/jats:title>\n                  <\/jats:sec>","DOI":"10.1016\/j.ijscr.2019.04.030","type":"journal-article","created":{"date-parts":[[2019,4,19]],"date-time":"2019-04-19T11:09:19Z","timestamp":1555672159000},"page":"104-107","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":17,"title":["Boerhaave's syndrome"],"prefix":"10.1097","volume":"58","author":[{"given":"Sara","family":"Catarino Santos","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruno","family":"Barbosa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Milene","family":"S\u00e1","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00falio","family":"Constantino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos","family":"Casimiro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-28-20260114","first-page":"161286","article-title":"Boerhaave's syndrome: still a diagnostic and therapeutic challenge in the 21st century","volume":"2013","author":"Spapen","year":"2013","journal-title":"Case Rep. Crit. Care"},{"key":"R2-28-20260114","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1590\/1516-3180.2016.0095220616","article-title":"Boerhaave syndrome\u2014case report","volume":"135","author":"Dinic","year":"2017","journal-title":"Sao Paulo Med. J"},{"key":"R3-28-20260114","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1186\/s12245-014-0027-2","article-title":"A rare case of oesophageal rupture: Boerhaave's syndrome","volume":"7","author":"van der Weg","year":"2014","journal-title":"Int. J. Emerg. Med"},{"key":"R4-28-20260114","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1016\/j.ijsu.2018.10.028","article-title":"The SCARE 2018 statement: updating consensus Surgical CAse REport (SCARE) guidelines","volume":"60","author":"Agha","year":"2018","journal-title":"Int. J. Surg"},{"key":"R5-28-20260114","doi-asserted-by":"crossref","first-page":"rju110","DOI":"10.1093\/jscr\/rju110","article-title":"Endoscopic management of Boerhaave's syndrome presenting with hematemesis","volume":"2014","author":"Fikfak","year":"2014","journal-title":"J. Surg. Case Rep"},{"key":"R6-28-20260114","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1155\/2018\/8483401","article-title":"The role of operation in the treatment of Boerhaave's syndrome","volume":"2018","author":"Han","year":"2018","journal-title":"BioMed Res. Int"},{"key":"R7-28-20260114","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1016\/j.thorsurg.2011.08.002","article-title":"Advances in the management of esophageal perforation","volume":"21","author":"Carrott","year":"2011","journal-title":"Thorac. Surg. Clin"},{"key":"R8-28-20260114","doi-asserted-by":"crossref","first-page":"rjv142","DOI":"10.1093\/jscr\/rjv142","article-title":"Boerhaave's syndrome presenting as a mid-esophageal perforation associated with a right-sided pleural effusion","volume":"2015","author":"Reardon","year":"2015","journal-title":"J. Surg. Case Rep"},{"key":"R9-28-20260114","doi-asserted-by":"crossref","first-page":"e1232","DOI":"10.1097\/MD.0000000000001232","article-title":"Esophageal perforation and acute bacterial mediastinitis: other causes of chest pain that can be easily missed","volume":"94","author":"Cross","year":"2015","journal-title":"Medicine (Baltimore"},{"key":"R10-28-20260114","first-page":"1","article-title":"Management and outcome of esophageal stenting for spontaneous esophageal perforations","volume":"30","author":"Glatz","year":"2017","journal-title":"Dis. 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Today"}],"container-title":["International Journal of Surgery Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2210261219302226?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2210261219302226?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.lww.com\/01612930-201958000-00028","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,14]],"date-time":"2026-01-14T13:06:42Z","timestamp":1768396002000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/01612930-201958000-00028"}},"subtitle":["A case report of damage control approach"],"short-title":[],"issued":{"date-parts":[[2019,1]]},"references-count":12,"journal-issue":{"issue":"C","published-print":{"date-parts":[[2019]]}},"URL":"https:\/\/doi.org\/10.1016\/j.ijscr.2019.04.030","relation":{},"ISSN":["2210-2612"],"issn-type":[{"value":"2210-2612","type":"print"}],"subject":[],"published":{"date-parts":[[2019,1]]}}}