{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,14]],"date-time":"2026-01-14T22:47:43Z","timestamp":1768430863395,"version":"3.49.0"},"reference-count":8,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"C","license":[{"start":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T00:00:00Z","timestamp":1546300800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T00:00:00Z","timestamp":1546300800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2019,10,18]],"date-time":"2019-10-18T00:00:00Z","timestamp":1571356800000},"content-version":"vor","delay-in-days":290,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2019,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Leiomyosarcoma is a rare soft tissue cancer that arises from smooth muscle cells that form involuntary muscles. Here, we report a rare case of retroperitoneal leiomyosarcoma that mimicked a metastatic tumor arising from a gastric cancer.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Presentation of case<\/jats:title>\n                    <jats:p>A 43-year-old man underwent radical total gastrectomy for gastric cancer. He underwent adjuvant chemotherapy with oral 5-fluorouracil (5-FU) for 2 years and regular follow-up. Twenty-nine months after gastrectomy, computed tomography (CT) was performed and revealed a solitary localized mass measuring 43 mm in diameter among retroperitoneal lymph nodes of the posterior inferior vena cava. This finding indicated that the previous gastric cancer recurred either in the lymph node or retroperitoneum. Second-line chemotherapy, consisting of oxaliplatin and 5-FU (FOLFOX) was administered in four cycles. However, serial CT scans showed increased tumor size. Retroperitoneal tumor did not respond to treatment, surgical resection was performed. Pathological findings led to a diagnosis of pleomorphic and epithelioid leiomyosarcoma without metastatic adenocarcinoma of the stomach.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>When a diagnosis of locoregional recurrence of gastric cancer in the retroperitoneum is considered, retroperitoneal leiomyosarcoma should also be considered in the differential diagnosis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Early diagnosis and concerted therapeutic efforts are important for managing misdiagnosed metastatic gastric cancer.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Highlights<\/jats:title>\n                  <\/jats:sec>","DOI":"10.1016\/j.ijscr.2019.10.028","type":"journal-article","created":{"date-parts":[[2019,10,21]],"date-time":"2019-10-21T12:46:36Z","timestamp":1571661996000},"page":"1-3","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Retroperitoneal leiomyosarcoma mimicking gastric cancer recurrence"],"prefix":"10.1097","volume":"65","author":[{"given":"Woo Yong","family":"Lee","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hye Kyeong","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"R1-1-20260114","doi-asserted-by":"crossref","first-page":"957","DOI":"10.1016\/j.hoc.2013.07.002","article-title":"Leiomyosarcoma","volume":"27","author":"Serrano","year":"2013","journal-title":"Hematol. Oncol. Clin. North Am"},{"key":"R2-1-20260114","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1007\/s00261-005-0163-5","article-title":"Abdominal aortic invasion by leiomyosarcoma","volume":"31","author":"Cantwell","year":"2006","journal-title":"Abdom. Imaging"},{"key":"R4-1-20260114","first-page":"784","article-title":"Smooth muscle tumors of the gastrointestinal tract and retroperitoneal tissues","volume":"73","author":"Golden","year":"1941","journal-title":"Surg. Gynecol. Obstet"},{"key":"R5-1-20260114","doi-asserted-by":"crossref","first-page":"688","DOI":"10.1177\/1538574412460102","article-title":"Leiomyosarcoma of the inferior vena cava: radical surgery without vascular reconstruction","volume":"46","author":"Drukker","year":"2012","journal-title":"Vasc. Endovasc. Surg"},{"key":"R6-1-20260114","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1097\/00000658-199809000-00008","article-title":"Retroperitoneal soft-tissue sarcoma: analysis of 500 patients treated and followed at a single institution","volume":"228","author":"Lewis","year":"1998","journal-title":"Ann. Surg"},{"key":"R7-1-20260114","doi-asserted-by":"crossref","first-page":"6191","DOI":"10.1007\/s13277-015-3304-7","article-title":"Prognostic significance of the recurrence pattern and risk factors for recurrence in patients with proximal gastric cancer who underwent curative gastrectomy","volume":"36","author":"Bilici","year":"2015","journal-title":"Tumour Biol"},{"key":"R8-1-20260114","doi-asserted-by":"crossref","first-page":"2069","DOI":"10.1200\/JCO.2004.08.026","article-title":"Extended lymph node dissection for gastric cancer: who may benefit? Final results of the randomized Dutch gastric cancer group trial","volume":"22","author":"Hartgrink","year":"2004","journal-title":"J. Clin. Oncol"},{"key":"R9-1-20260114","doi-asserted-by":"crossref","first-page":"1107","DOI":"10.1016\/S0022-5347(17)41184-0","article-title":"Sarcomas of the retroperitoneum and genitourinary tract","volume":"141","author":"Zhang","year":"1989","journal-title":"J. Urol"}],"container-title":["International Journal of Surgery Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2210261219305747?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2210261219305747?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.lww.com\/01612930-201965000-00001","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,14]],"date-time":"2026-01-14T13:03:37Z","timestamp":1768395817000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/01612930-201965000-00001"}},"subtitle":["A case report"],"short-title":[],"issued":{"date-parts":[[2019,1]]},"references-count":8,"journal-issue":{"issue":"C","published-print":{"date-parts":[[2019]]}},"URL":"https:\/\/doi.org\/10.1016\/j.ijscr.2019.10.028","relation":{},"ISSN":["2210-2612"],"issn-type":[{"value":"2210-2612","type":"print"}],"subject":[],"published":{"date-parts":[[2019,1]]}}}