{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,14]],"date-time":"2026-01-14T23:47:04Z","timestamp":1768434424554,"version":"3.49.0"},"reference-count":14,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"C","license":[{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2020,3,5]],"date-time":"2020-03-05T00:00:00Z","timestamp":1583366400000},"content-version":"vor","delay-in-days":64,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2020,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Osteomyelitis is an inflammatory-infectious state that may involve trabecular bone, cortical bone, bone marrow and periosteum. The source of the infection may be hematogenic, acquired from an adjoining infectious focus or by direct inoculation into the bone. Its treatment involves antibiotic administration and surgery, but its management remains challenging.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Presentation of case<\/jats:title>\n                    <jats:p>A 76-year-old male patient with a history of car accident 3 months earlier sought hospital care with nasal fracture and loss of substance in the right frontotemporal region, where a pectoral muscle free graft was performed to reconstruct the facial defect. The grafted region had hyperemic edges, necrotic appearance, purulent discharge and bone exposure in the nasal dorsum. The initial diagnostic hypothesis was an infectious process due to graft rejection, with likely evolution to osteomyelitis. The surgical procedure was performed by a multidisciplinary team and the patient received the antibiotic regimen according to the antibiogram, with hospital discharge after 39 days of hospitalization.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>Treatment of osteomyelitis requires the combination of antimicrobial therapy and surgery. Despite surgical and chemotherapeutic advances, it is a difficult condition to treat and there is no universally accepted protocol for treatment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Surgical treatment was essential for stabilization of the condition. Due to the complexity of this type of infection in the craniofacial region, planning and execution must be carried out through a multidisciplinary team.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1016\/j.ijscr.2020.03.009","type":"journal-article","created":{"date-parts":[[2020,3,7]],"date-time":"2020-03-07T11:41:25Z","timestamp":1583581285000},"page":"246-250","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Facial trauma followed by osteomyelitis - Case report"],"prefix":"10.1097","volume":"68","author":[{"given":"Gabriela Caovilla","family":"Felin","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cassian","family":"Taparello","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vinicios","family":"Fornari","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paulo Mesquita","family":"Filho","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J\u00fanior","family":"Grandii","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Let\u00edcia Copatti","family":"Dogenski","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jo\u00e3o Paulo","family":"De Carli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"R1-58-20260114","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1097\/CNQ.0000000000000056","article-title":"Osteomyelitis: an overview of imaging modalities","volume":"38","author":"Bires","year":"2017","journal-title":"Crit. Care Nurs. Q"},{"key":"R2-58-20260114","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1016\/j.surge.2015.12.005","article-title":"The management of osteomyelitis in the adult","volume":"14","author":"Maffulli","year":"2016","journal-title":"Surgeon"},{"key":"R3-58-20260114","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1016\/j.jormas.2017.04.007","article-title":"Osteomyelitis of the jaws: a retrospective series of 40 patients","volume":"118","author":"Andre","year":"2017","journal-title":"J. Stomatol. Oral Maxillofac. Surg"},{"key":"R4-58-20260114","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1097\/01.ASW.0000532737.64628.2a","article-title":"Osteomyelitis: a context for wound management","volume":"31","author":"Groll","year":"2018","journal-title":"Adv. Skin Wound Care"},{"key":"R5-58-20260114","first-page":"217","article-title":"Bacterial osteomyelitis: microbiological, clinical, therapeutic, and evolutive characteristics of 344 episodes","volume":"31","author":"Del Pozo","year":"2018","journal-title":"Rev. Esp. Quimioter"},{"key":"R6-58-20260114","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1016\/j.wneu.2017.12.066","article-title":"Cranial osteomyelitis: a comprehensive review of modern therapies","volume":"111","author":"Mortazavi","year":"2018","journal-title":"World Neurosurg"},{"key":"R7-58-20260114","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1016\/j.ijsu.2018.10.028","article-title":"The SCARE 2018 statement: updating consensus surgical case report (scare) guidelines","volume":"60","author":"Agha","year":"2018","journal-title":"Int. J. Surg"},{"key":"R8-58-20260114","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1016\/j.ijantimicag.2019.01.007","article-title":"Short course versus long course antibiotics in osteomyelitis: a systematic review and meta-analysis","volume":"53","author":"Huang","year":"2019","journal-title":"Int. J. Antimicrob. Agents"},{"key":"R9-58-20260114","doi-asserted-by":"crossref","first-page":"837","DOI":"10.2106\/JBJS.N.01350","article-title":"Trends in the epidemiology of osteomyelitis: a population-based study, 1969 to 2009","volume":"97","author":"Kremers","year":"2015","journal-title":"J. Bone Joint Surg. Am"},{"key":"R10-58-20260114","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1093\/rheumatology\/kex066","article-title":"Chronic recurrent multifocal osteomyelitis in children and adults: current understanding and areas for development","volume":"57","author":"Roderick","year":"2018","journal-title":"Rheumatology (Oxford"},{"key":"R11-58-20260114","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/j.cden.2016.12.001","article-title":"Microbiology of acute and chronic osteomyelitis and antibiotic treatment","volume":"61","author":"Dym","year":"2017","journal-title":"Dent. Clin. North Am"},{"key":"R12-58-20260114","doi-asserted-by":"crossref","first-page":"1204","DOI":"10.1097\/INF.0000000000001991","article-title":"Osteoarticular infections following open or penetrating trauma in children in the post-community-acquired methicillin-resistant Staphylococcus aureus era: the impact of Enterobacter cloacae","volume":"37","author":"McNeil","year":"2018","journal-title":"Pediatr. Infect. Dis. J"},{"key":"R13-58-20260114","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1016\/j.joms.2016.08.018","article-title":"Osteomyelitis of the mandibular condyle: a report of 2 cases with review of literature","volume":"75","author":"Chattopadhyay","year":"2017","journal-title":"J. Oral Maxillofac. Surg"},{"key":"R14-58-20260114","doi-asserted-by":"crossref","first-page":"e0149389","DOI":"10.1371\/journal.pone.0149389","article-title":"Surgical debridement is superior to sole antibiotic therapy in a novel murine posttraumatic osteomyelitis model","volume":"11","author":"Wagner","year":"2016","journal-title":"PLoS One"}],"container-title":["International Journal of Surgery Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2210261220301504?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2210261220301504?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.lww.com\/10.1016\/j.ijscr.2020.03.009","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,14]],"date-time":"2026-01-14T13:11:10Z","timestamp":1768396270000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/10.1016\/j.ijscr.2020.03.009"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,1]]},"references-count":14,"journal-issue":{"issue":"C","published-print":{"date-parts":[[2020]]}},"URL":"https:\/\/doi.org\/10.1016\/j.ijscr.2020.03.009","relation":{},"ISSN":["2210-2612"],"issn-type":[{"value":"2210-2612","type":"print"}],"subject":[],"published":{"date-parts":[[2020,1]]}}}