{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T14:26:17Z","timestamp":1783607177658,"version":"3.55.0"},"reference-count":9,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"C","license":[{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2020,10,16]],"date-time":"2020-10-16T00:00:00Z","timestamp":1602806400000},"content-version":"vor","delay-in-days":289,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2020,1]]},"abstract":"Abstract<\/jats:title>\n \n Introduction<\/jats:title>\n The simultaneous appearance of several primary cancers is rare.<\/jats:p>\n <\/jats:sec>\n \n Presentation<\/jats:title>\n We report the case of a 77-year-old man admitted to the Mohammed V military hospital in Rabat (university hospital) and presenting severe dysuria on the PSA test which was 10.83 ng \/ ml. The prostate MRI performed revealed a suspected lesion. He had left renal colic associated with hematuria two weeks later. A CT scan of the abdomen and pelvis performed revealed a 14 \u00d7 12 mm middle and lower calyx excretory tract tumor on the left and a 27.6 \u00d7 26.4 lower right polar kidney tumor enhanced after injection of product from contrast. The prostate biopsy confirmed an adenocarcinoma of the prostate. He first underwent a left nephroureterectomy for the tumor of the excretory tract, followed by radiotherapy combined with hormone therapy for his adenocarcinoma. It was decided to monitor the tumor of the right kidney.<\/jats:p>\n <\/jats:sec>\n \n Discussion<\/jats:title>\n The literature contains only a few case reports and reviews of patients with three or more synchronous malignancies. We report the case of a man in whom three different cancers were found over a period of three months. The patient had no significant medical history, such as a family history of cancer or chemotherapy other than old age and chronic smoking. Therefore, we suggest that these factors may favor the occurrence of several synchronous primary cancers.<\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n There is no consensus on the treatment of multiple malignant tumors. Patient care is individual, by a multidisciplinary team, accounting for the type and the stage of each tumor with a more conservative approach.<\/jats:p>\n <\/jats:sec>\n \n Highlights<\/jats:title>\n <\/jats:sec>","DOI":"10.1016\/j.ijscr.2020.10.061","type":"journal-article","created":{"date-parts":[[2020,10,20]],"date-time":"2020-10-20T01:28:12Z","timestamp":1603157292000},"page":"501-504","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":3,"title":["Three simultaneous primary urologic malignancies iA single patient"],"prefix":"10.1097","volume":"76","author":[{"given":"Ilias","family":"Hassan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Larbi","family":"Hamedoun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamed","family":"Tetou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamed","family":"Mrabti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamed","family":"Alami","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmed","family":"Ameur","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-113-20260114","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1186\/s12891-020-03426-8","article-title":"Multiple primary tumors: a case report and review of the literature","volume":"21","author":"Zhao","year":"2020","journal-title":"BMC Musculoskelet. Disord"},{"key":"R2-113-20260114","first-page":"1358","article-title":"Multiple primary malignant tumours: a survey of the literature and a statistical study","volume":"16","author":"Warren","year":"1932","journal-title":"Am. J. Cancer"},{"key":"R3-113-20260114","first-page":"2953","article-title":"Report of two cases of quintuple primary malignancies and review of the literature","volume":"28","author":"Cercato","year":"2008","journal-title":"Anticancer Res"},{"key":"R4-113-20260114","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1016\/j.ijsu.2018.10.028","article-title":"The SCARE 2018 statement: updating consensus surgical CAse REport (SCARE) guidelines","volume":"60","author":"Agha","year":"2018","journal-title":"Int. J. Surg"},{"key":"R5-113-20260114","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/0090-4295(92)90296-9","article-title":"Multiple primary cancers in urologic patients. Audit of 19-year experience in Berlin and review of the literature","volume":"39","author":"Wegner","year":"1992","journal-title":"Urology"},{"key":"R6-113-20260114","first-page":"1565","article-title":"Synchronous and metachronous malignancies: analysis of the Minneapolis Veterans Affairs (VA) tumor registry","volume":"24","author":"Powell","year":"2013","journal-title":"Cancer Causes Control"},{"key":"R7-113-20260114","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1097\/00000658-196611000-00001","article-title":"Incidence of multiple primary cancers per man-year of follow up: 20-year review from the Ellis Fischel State Cancer Hospital","volume":"164","author":"Spratt","year":"1966","journal-title":"Ann. Surg"},{"key":"R8-113-20260114","doi-asserted-by":"crossref","first-page":"330","DOI":"10.4111\/icu.2016.57.5.330","article-title":"Second primary cancers in patients with urothelial cancers","volume":"57","author":"\u015eahin","year":"2016","journal-title":"Invest. Clin. 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