{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T16:54:43Z","timestamp":1789232083093,"version":"build-2803163510"},"reference-count":17,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"C","license":[{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,1,11]],"date-time":"2021-01-11T00:00:00Z","timestamp":1610323200000},"content-version":"vor","delay-in-days":10,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Although primary cystic duct cancer is a rare entity, remnant cystic duct cancer is even more rare. We report a case of early cystic duct cancer following cholecystectomy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Presentation of the case<\/jats:title>\n                    <jats:p>A 81 year-old man complained temporary loss of appetite. He had underwent cholecystectomy for acute cholecystitis 5 years prior. Contrast enhanced computed tomography, magnetic resonance image and endoscopic ultrasonography showed remnant cystic duct tumor with protrusion to common bile duct. Endoscopic retrograde cholangiography revealed defect of contrast medium around confluence of the remnant cystic duct and common bile duct. We performed step biopsy by using forceps which revealed adenocarcinoma. Based on these findings, extrahepatic bile duct and remnant cystic duct resection were performed. The histopathology showed adenocarcinoma, pap &gt; tub2, filling in remnant cystic duct, 30 mm in size but showed no lymphovascular or perineural invasion, no lymph node metastasis and negative surgical margin, and was classified as pT1bN0M0.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This is a rare case of primary carcinoma of remnant cystic duct cancer which is detected during computed tomography follow up for hepatic cell carcinoma recurrence. We confirmed remnant cystic duct cancer and its superficial extension to common bile duct with endoscopic ultrasonography and intraductal ultrasonography. Proper curative surgery was performed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Highlights<\/jats:title>\n                  <\/jats:sec>","DOI":"10.1016\/j.ijscr.2021.01.030","type":"journal-article","created":{"date-parts":[[2021,1,18]],"date-time":"2021-01-18T03:10:50Z","timestamp":1610939450000},"page":"307-311","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":5,"title":["T1b primary remnant cystic duct cancer following cholecystectomy"],"prefix":"10.1097","volume":"79","author":[{"given":"Muneji","family":"Yasuda","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuichi","family":"Tanaka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shinji","family":"Miyajima","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haruo","family":"Takaya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toyokazu","family":"Fukunaga","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kozo","family":"Kajimura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R2-69-20260114","doi-asserted-by":"crossref","first-page":"6541","DOI":"10.3748\/wjg.v25.i44.6541","article-title":"Cystic duct cancer: should it be deemed as a type of gallbladder cancer?","volume":"25","author":"Yu","year":"2019","journal-title":"World J. Gastroenterol"},{"key":"R3-69-20260114","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1002\/bjs.18003915414","article-title":"Carcinoma of the cystic duct","volume":"39","author":"Farrar","year":"1951","journal-title":"Br. J. Surg"},{"key":"R4-69-20260114","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1007\/s00423-002-0333-7","article-title":"Cystic duct carcinoma: a proposal for a new \u201cworking definition\u201d","volume":"387","author":"Ozden","year":"2003","journal-title":"Langenbecks Arch. Surg"},{"key":"R5-69-20260114","first-page":"357","article-title":"Carcinoma of the major intrahepatic and the extrahepatic bile ducts exclusive of the papilla of Vater","volume":"104","author":"Kuwayti","year":"1957","journal-title":"Surg. Gynecol. Obstet"},{"key":"R6-69-20260114","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1001\/archsurg.1969.01340080117026","article-title":"Primary adenocarcinoma in a cystic duct stump. Report of a case and review of the literature","volume":"98","author":"Phillips","year":"1969","journal-title":"Arch. Surg"},{"key":"R7-69-20260114","doi-asserted-by":"crossref","first-page":"610","DOI":"10.1016\/0002-9610(71)90151-6","article-title":"Primary adenocarcinoma in cystic duct remnants","volume":"121","author":"Dixon","year":"1971","journal-title":"Am. J. Surg"},{"key":"R8-69-20260114","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1007\/s00261-001-0159-8","article-title":"Cystic duct remnant carcinoma with widespread invasion along the extrahepatic bile duct wall: dynamic CT findings","volume":"28","author":"Gabata","year":"2003","journal-title":"Abdom. Imaging"},{"key":"R9-69-20260114","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1385\/IJGC:34:2-3:117","article-title":"Carcinoma of the cystic duct remnant with direct colonic invasion","volume":"34","author":"Noji","year":"2003","journal-title":"Int. J. Gastrointest. Cancer"},{"key":"R10-69-20260114","doi-asserted-by":"crossref","first-page":"975","DOI":"10.1016\/j.gie.2007.11.010","article-title":"A remnant cystic duct cancer presenting as a duodenal submucosal tumor","volume":"67","author":"Eum","year":"2008","journal-title":"Gastrointest. Endosc"},{"key":"R11-69-20260114","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1186\/1471-230X-14-175","article-title":"Adenocarcinoma developed from remnant cystic duct after cholecystectomy","volume":"14","author":"Do","year":"2014","journal-title":"BMC Gastroenterol"},{"key":"R12-69-20260114","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1186\/s12893-019-0647-9","article-title":"Early-stage T1b adenocarcinoma arising in the remnant cystic duct after laparoscopic cholecystectomy: a case report and literature review","volume":"19","author":"Prasoon","year":"2019","journal-title":"BMC Surg"},{"key":"R13-69-20260114","doi-asserted-by":"crossref","first-page":"e194","DOI":"10.1200\/EDBK_160831","article-title":"Biliary tract cancer: epidemiology, radiotherapy, and molecular profiling","volume":"35","author":"Bridgewater","year":"2016","journal-title":"Am. Soc. Clin. Oncol. Educ. Book"},{"key":"R14-69-20260114","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1002\/jhbp.211","article-title":"Classification of biliary tract cancers established by the Japanese Society of Hepato-Biliary-Pancreatic Surgery: 3(rd) English edition","volume":"22","author":"Miyazaki","year":"2015","journal-title":"J. Hepatobiliary Pancreat Sci"},{"key":"R15-69-20260114","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1007\/BF02471720","article-title":"Early carcinoma of the extrahepatic bile duct","volume":"19","author":"Tsunoda","year":"1989","journal-title":"Jpn. J. Surg"},{"key":"R16-69-20260114","first-page":"69","article-title":"Definition and diagnosis of early cancer of the biliary tract","volume":"40","author":"Mizumoto","year":"1993","journal-title":"Hepatogastroenterology"},{"key":"R17-69-20260114","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1002\/1097-0142(19840701)54:1<65::AID-CNCR2820540115>3.0.CO;2-0","article-title":"Evolution of carcinoma in the extrahepatic bile ducts","volume":"54","author":"Kozuka","year":"1984","journal-title":"Cancer"},{"key":"R18-69-20260114","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1007\/s005350170006","article-title":"Cholangiographic findings of early-stage extrahepatic bile duct carcinoma","volume":"36","author":"Tamada","year":"2001","journal-title":"J. Gastroenterol"}],"container-title":["International Journal of Surgery Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2210261221000328?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2210261221000328?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.lww.com\/10.1016\/j.ijscr.2021.01.030","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,14]],"date-time":"2026-01-14T13:29:56Z","timestamp":1768397396000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/10.1016\/j.ijscr.2021.01.030"}},"subtitle":["A case report"],"short-title":[],"issued":{"date-parts":[[2021,1]]},"references-count":17,"journal-issue":{"issue":"C","published-print":{"date-parts":[[2021]]}},"URL":"https:\/\/doi.org\/10.1016\/j.ijscr.2021.01.030","relation":{},"ISSN":["2210-2612"],"issn-type":[{"value":"2210-2612","type":"print"}],"subject":[],"published":{"date-parts":[[2021,1]]}}}