{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,24]],"date-time":"2026-06-24T20:18:39Z","timestamp":1782332319021,"version":"3.54.5"},"reference-count":16,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"C","license":[{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,1,18]],"date-time":"2021-01-18T00:00:00Z","timestamp":1610928000000},"content-version":"vor","delay-in-days":17,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction and importance<\/jats:title>\n                    <jats:p>A Morel-Lavallee lesion is a closed degloving injury due to traumatic separation of the hypodermis from underlying fascia. Accumulation of hemolymphatic fluid that occurs is a potential habitat for bacteria. Management options include percutaneous aspiration, open debridement, or a non-surgical approach, each with recurrence risk. In the event of recurrence, sclerotherapy is used. In this case report, after reviewing povidone iodine's efficacy in treating seromas, we used it as a sclerosant for recurrent Morel-Lavallee lesion as the more established options were unavailable in our setting.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case presentation<\/jats:title>\n                    <jats:p>A 49-year-old with no known comorbid presented following a motor traffic accident, with left lateral thigh swelling. He was stable systematically, with a tense, tender left lateral thigh swelling and intact neurovascular assessment distally. X-ray and computed tomography ruled out skeletal and vascular injuries. Magnetic resonance imaging revealed a 580 ml type 1 Morell-Lavallee lesion. Open surgical debridement was done to drain and debride the lesion. He developed two recurrences that necessitated percutaneous aspiration. Doxycycline and talc sclerosants were considered; however, due to their unavailability, povidone iodine was used. It is now five months post-intervention without increased pain, recurrence, or wound complications.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Clinical discussion<\/jats:title>\n                    <jats:p>Recurrence is hypothesized to be due to the persistence of fluid loculations, unobliterated dead space, and pseudocyst formation. Sclerotherapy stimulates inflammation that results in fibrosis of the cavity walls causing its obliteration. Doxycycline, the most studied sclerosant in Morel-Lavall\u00e9e lesion has an efficacy of 95.7%.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The current report is the first successful use of povidone iodine for sclerotherapy of recurring Morel-Lavall\u00e9e lesions. Based on povidone iodine experiences as a sclerosant, it is associated with increased analgesic requirements. We cautiously propose its use as an alternative in settings where talc powder and doxycycline powder are unavailable.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Highlights<\/jats:title>\n                  <\/jats:sec>","DOI":"10.1016\/j.ijscr.2021.01.067","type":"journal-article","created":{"date-parts":[[2021,1,20]],"date-time":"2021-01-20T02:20:10Z","timestamp":1611109210000},"page":"343-349","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":3,"title":["Recurrent Morel-Lavall\u00e9e lesion obliterated with povidone iodine, a case report"],"prefix":"10.1097","volume":"79","author":[{"given":"Allyzain","family":"Ismail","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masawa","family":"Nyamuryekung'e","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kumar","family":"Rajeev","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-77-20260114","first-page":"300","article-title":"Decollements traumatiques de la peau et des couches sous-jacentes","volume":"1","author":"Morel-Lavall\u00e9e","year":"1863","journal-title":"Arch. Gen. Med"},{"key":"R3-77-20260114","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1016\/j.mric.2005.08.006","article-title":"Morel-Lavall\u00e9e lesion: review with emphasis on MR imaging","volume":"13","author":"Mellado","year":"2005","journal-title":"Magn. Reson. Imaging Clin"},{"key":"R4-77-20260114","doi-asserted-by":"crossref","first-page":"667","DOI":"10.5435\/JAAOS-D-15-00181","article-title":"The Morel-Lavall\u00e9e lesion: diagnosis and management","volume":"24","author":"Scolaro","year":"2016","journal-title":"J. Am. Acad. Orthop. Surg"},{"key":"R6-77-20260114","doi-asserted-by":"crossref","first-page":"1046","DOI":"10.1097\/00005373-199706000-00010","article-title":"Diagnosis and management of closed internal degloving injuries associated with pelvic and acetabular fractures: the Morel-Lavallee lesion","volume":"42","author":"Hak","year":"1997","journal-title":"J. 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Surg"},{"key":"R10-77-20260114","first-page":"357","article-title":"Randomized phase II study of talc versus iodopovidone for the prevention of seroma formation following modified radical mastectomy","volume":"67","author":"Garza-Gangemi","year":"2016","journal-title":"Rev. Invest. Cl\u00edn"},{"key":"R12-77-20260114","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1097\/TA.0000000000000111","article-title":"The Mayo Clinic experience with Morel-Lavall\u00e9e lesions: establishment of a practice management guideline","volume":"76","author":"Nickerson","year":"2014","journal-title":"J. Trauma Acute Care Surg"},{"key":"R13-77-20260114","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1097\/BOT.0b013e31802f19ca","article-title":"Morel-Laval\u00e9e lesions treated with debridement and meticulous dead space closure: surgical technique","volume":"21","author":"Carlson","year":"2007","journal-title":"J. Orthop. Trauma"},{"key":"R14-77-20260114","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1097\/00006534-199205000-00013","article-title":"Closed degloving injuries: results following conservative surgery","volume":"89","author":"Hudson","year":"1992","journal-title":"Plast. Reconstr. Surg"},{"key":"R15-77-20260114","first-page":"92","article-title":"Percutaneous management of Morel-Lavallee lesions","volume":"88","author":"Tseng","year":"2006","journal-title":"JBJS"},{"key":"R16-77-20260114","doi-asserted-by":"crossref","first-page":"e262","DOI":"10.1016\/j.bjps.2011.06.012","article-title":"Alcohol sclerodhesis: an innovative treatment for chronic Morel-Lavall\u00e9e lesions","volume":"64","author":"Penaud","year":"2011","journal-title":"J. Plast. Reconstr. 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