{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,14]],"date-time":"2026-01-14T23:55:32Z","timestamp":1768434932102,"version":"3.49.0"},"reference-count":9,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"C","license":[{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,2,8]],"date-time":"2021-02-08T00:00:00Z","timestamp":1612742400000},"content-version":"vor","delay-in-days":38,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2021,1]]},"abstract":"Abstract<\/jats:title>\n \n Introduction and importance<\/jats:title>\n We report the case of a patient with a low-grade appendiceal mucinous neoplasm (LAMN) who underwent emergency laparoscopic ileocecal resection to avoid the metastatic spread of tumor cells due to an impending rupture.<\/jats:p>\n <\/jats:sec>\n \n Case presentation<\/jats:title>\n A 55-year-old woman presented to our hospital with pain in the right lower quadrant of the abdomen. Computed tomography revealed a markedly tense appendiceal mucinous tumor with surrounding inflammation, and laboratory test results showed elevated serum C-reactive protein (7.47 mg\/dL), indicating impending rupture of the appendix. Magnetic resonance imaging revealed nodules inside the appendix, suggesting the possibility of appendiceal cancer. We performed emergency laparoscopic ileocecal resection with regional lymph node dissection. The tumor was pathologically diagnosed as a LAMN without rupture.<\/jats:p>\n <\/jats:sec>\n \n Clinical discussion<\/jats:title>\n LAMN is classified as a clinically malignant tumor because it can cause pseudomyxoma peritonei due to perforation or the presence of residual tissue. Although an appendectomy would be appropriate for LAMN if the tumor margin is secured, ileocecal resection with lymph node dissection is necessary when preoperative discrimination of appendiceal cancer is impossible.<\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n Further studies of preoperative imaging for appropriate differential diagnosis were necessary.<\/jats:p>\n <\/jats:sec>\n \n Highlights<\/jats:title>\n <\/jats:sec>","DOI":"10.1016\/j.ijscr.2021.02.022","type":"journal-article","created":{"date-parts":[[2021,2,9]],"date-time":"2021-02-09T21:32:51Z","timestamp":1612906371000},"page":"105636","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":3,"title":["Emergency laparoscopic ileocecal resection for a low-grade appendiceal mucinous neoplasm with impending rupture"],"prefix":"10.1097","volume":"80","author":[{"given":"Yusuke","family":"Kitagawa","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shunsuke","family":"Hamasaki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Toshiko","family":"Harada","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Noriyasu","family":"Tamura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akira","family":"Katsuno","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naoyuki","family":"Umetani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"R1-53-20260114","doi-asserted-by":"crossref","first-page":"1107","DOI":"10.1634\/theoncologist.2017-0081","article-title":"Appendiceal mucinous neoplasms: diagnosis and management","volume":"22","author":"Shaib","year":"2017","journal-title":"Oncologist"},{"key":"R2-53-20260114","first-page":"1","article-title":"Analysis of clinical characteristics of low-grade appendiceal mucinous neoplasm (LAMN): a retrospective cohort study of 51 LAMN patients","volume":"6","author":"Xiao","year":"2020","journal-title":"J. Invest. Surg"},{"key":"R3-53-20260114","doi-asserted-by":"crossref","first-page":"S67","DOI":"10.1038\/modpathol.2014.129","article-title":"Mucinous epithelial neoplasms of the appendix and pseudomyxoma peritonei","volume":"28","author":"Misdraji","year":"2015","journal-title":"Mod. Pathol"},{"key":"R4-53-20260114","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1245\/s10434-016-5588-2","article-title":"Low-grade appendiceal mucinous neoplasm of uncertain malignant potential (LAMN-UMP): prognostic factors and implications for treatment and follow-up","volume":"24","author":"Fournier","year":"2017","journal-title":"Ann. Surg. Oncol"},{"key":"R5-53-20260114","doi-asserted-by":"crossref","first-page":"518","DOI":"10.5858\/arpa.2014-0246-OA","article-title":"Significance of proximal margin involvement in low-grade appendiceal mucinous neoplasms","volume":"139","author":"Arnason","year":"2015","journal-title":"Arch. Pathol. Lab. Med"},{"key":"R6-53-20260114","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1102\/1470-7330.2013.0003","article-title":"Mucinous neoplasms of the appendix: a current comprehensive clinicopathologic and imaging review","volume":"13","author":"Tirumani","year":"2013","journal-title":"Cancer Imaging"},{"key":"R7-53-20260114","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1016\/j.ijsu.2020.10.034","article-title":"The SCARE 2020 guideline: updating consensus surgical CAse REport (SCARE) guidelines","volume":"84","author":"Agha","year":"2020","journal-title":"Int. J. Surg"},{"key":"R8-53-20260114","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1136\/jim-2018-000975","article-title":"Low-grade appendiceal mucinous neoplasms confined to the appendix: clinical manifestations and CT findings","volume":"68","author":"Yu","year":"2020","journal-title":"J. Investig. 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Colon Rectal Surg"}],"container-title":["International Journal of Surgery Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2210261221001322?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2210261221001322?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.lww.com\/10.1016\/j.ijscr.2021.02.022","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,14]],"date-time":"2026-01-14T13:37:59Z","timestamp":1768397879000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/10.1016\/j.ijscr.2021.02.022"}},"subtitle":["A case report"],"short-title":[],"issued":{"date-parts":[[2021,1]]},"references-count":9,"journal-issue":{"issue":"C","published-print":{"date-parts":[[2021]]}},"URL":"https:\/\/doi.org\/10.1016\/j.ijscr.2021.02.022","relation":{},"ISSN":["2210-2612"],"issn-type":[{"value":"2210-2612","type":"print"}],"subject":[],"published":{"date-parts":[[2021,1]]}}}