{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,14]],"date-time":"2026-01-14T23:21:54Z","timestamp":1768432914897,"version":"3.49.0"},"reference-count":14,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"C","license":[{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,4,8]],"date-time":"2021-04-08T00:00:00Z","timestamp":1617840000000},"content-version":"vor","delay-in-days":97,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Neurofibromatosis is a disease that causes various abnormalities such as neurofibroma, mainly in the skin and nerves. The common sites in the oral cavity are the palate, gingiva, tongue, buccal mucosa, and lips but, occurrence in the mandible is rare.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Presentation of case<\/jats:title>\n                    <jats:p>A 26-year-old woman was referred to our clinic because of percussion pain. Radiographic findings showed a radiolucent area. The patient was clinically diagnosed with a radicular cyst by a previous doctor. Multiple caf\u00e9-au-lait spots were found disseminated on her body, and she had already been prenatally diagnosed with neurofibromatosis type 1 (NF1). We performed a biopsy and suggested a neurofibroma. Tumor extirpation was performed under general anesthesia. The histopathological diagnosis showed a neurofibroma.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Clinical discussion and conclusion<\/jats:title>\n                    <jats:p>NF1 is a systemic nevus that causes abnormalities in melanocytes and Schwann cells, and various lesions appear, but intramandibular lesions are extremely rare. Diagnosis of NF1 and radicular cysts in the mandible is difficult due to their image resemblance. However, it should be kept in mind if the underlying disease is NF1. In our case, it was easy to detach and may have originated from small peripheral nerve endings in the mandible.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Highlights<\/jats:title>\n                  <\/jats:sec>","DOI":"10.1016\/j.ijscr.2021.105883","type":"journal-article","created":{"date-parts":[[2021,4,13]],"date-time":"2021-04-13T23:53:45Z","timestamp":1618358025000},"page":"105883","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":3,"title":["A case of intramandibular neurofibroma resembling a radicular cyst in a neurofibromatosis type 1 patient"],"prefix":"10.1097","volume":"82","author":[{"given":"Yuki","family":"Kunisada","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Norie","family":"Yoshioka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Soichiro","family":"Ibaragi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tatsuo","family":"Okui","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hitoshi","family":"Nagatsuka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akira","family":"Sasaki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"R1-37-20260114","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/0030-4220(55)90349-2","article-title":"Multiple neurofibromatosis with oral lesions; review of the literature and report of a case","volume":"8","author":"Baden","year":"1955","journal-title":"Oral Surg. Oral Med. Oral Pathol"},{"key":"R2-37-20260114","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1016\/j.ijsu.2020.10.034","article-title":"The SCARE 2020 guideline: updating consensus Surgical CAse REport (SCARE) guidelines","volume":"84","author":"Agha","year":"2020","journal-title":"Int. J. 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Genet"},{"key":"R6-37-20260114","first-page":"575","article-title":"Neurofibromatosis: conference statement","volume":"45","author":"National Institute of Health consensus development Conference 1987","year":"1987","journal-title":"Arch. Neurol"},{"key":"R7-37-20260114","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1007\/BF00220540","article-title":"Genetics of neurofibromatosis 1 in Japan: mutation rate and paternal age effect","volume":"89","author":"Takano","year":"1992","journal-title":"Hum. Genet"},{"key":"R8-37-20260114","doi-asserted-by":"crossref","first-page":"813","DOI":"10.1001\/archsurg.1952.01260010833013","article-title":"Cutaneous neurofibromatosis (von Recklinghausen\u2019s disease); clinical manifestation and incidence of sarcoma in sixty-one male patients","volume":"64","author":"Preston","year":"1952","journal-title":"AMA Arch. Surg"},{"key":"R10-37-20260114","first-page":"382","article-title":"A case of von Recklinghausen\u2019s disease with a neurofibroma of the lower gingiva","volume":"51","author":"Kitajima","year":"2002","journal-title":"J. Jpn. Stomatol. Soc"},{"key":"R11-37-20260114","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1016\/0030-4220(84)90350-5","article-title":"Neurofibromatosis: oral and radiographic manifestations","volume":"58","author":"Shapiro","year":"1984","journal-title":"Oral Surg. Oral Med. Oral Pathol"},{"key":"R12-37-20260114","doi-asserted-by":"crossref","first-page":"634","DOI":"10.5794\/jjoms.30.634","article-title":"Report of a case of neurofibroma of the left mandible resembling a bone cyst in a patient with von Recklinghausen\u2019s disease","volume":"30","author":"Goto","year":"1984","journal-title":"Jpn. J. Oral Maxillofac. Surg"},{"key":"R13-37-20260114","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1186\/s13023-018-0881-8","article-title":"Craniofacial and oral alterations in patients with Neurofibromatosis 1","volume":"13","author":"Visnapuu","year":"2018","journal-title":"Orphanet J. Rare Dis"},{"key":"R14-37-20260114","doi-asserted-by":"crossref","first-page":"582","DOI":"10.2214\/AJR.07.2589","article-title":"Imaging appearance of diffuse neurofibroma","volume":"190","author":"Hassell","year":"2008","journal-title":"Am. J. Roentgenol"},{"key":"R15-37-20260114","first-page":"97","article-title":"Solitary intraosseous neurofibroma of the mandible: report of a case","volume":"55","author":"Ueda","year":"1993","journal-title":"Nagoya J. Med. Sci"}],"container-title":["International Journal of Surgery Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2210261221003850?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2210261221003850?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.lww.com\/10.1016\/j.ijscr.2021.105883","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,14]],"date-time":"2026-01-14T13:03:02Z","timestamp":1768395782000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/10.1016\/j.ijscr.2021.105883"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,1]]},"references-count":14,"journal-issue":{"issue":"C","published-print":{"date-parts":[[2021]]}},"URL":"https:\/\/doi.org\/10.1016\/j.ijscr.2021.105883","relation":{},"ISSN":["2210-2612"],"issn-type":[{"value":"2210-2612","type":"print"}],"subject":[],"published":{"date-parts":[[2021,1]]}}}